Center of Immunology Publications list

103. Bostan I.S., Mihaila M., Roman V., Radu N., Neagu M.T., Bostan M., Mehedintu C. Landscape of endometrial cancer: Molecular mechanisms, biomarkers, and target therapy. Cancers Jun 2024, 16, doi:10.3390/cancers16112027.

102. Ivan I.M., Olaru O.T., Popovici V., Chitescu C.L., Popescu L., Luta E.A., Ilie E.I., Brasoveanu L.I., Hotnog C.M., Nitulescu G.M., Boscencu R., Gîrd C.E. Antioxidant and cytotoxic properties of Berberis vulgaris (L.) stem bark dry extract. Molecules May 2024, 29, doi:10.3390/molecules29092053.

101. Campanella A., Capasso A., Heltai S., Taccetti C., Albi E., Herishanu Y., Haggenburg S., Chatzikonstantinou T., Doubek M., Kättström M., Giannopoulos K., Simkovic M., Moreno C., Massaia M., Bumbea H., Alshemmari S., Ranghetti P., Perotta E., Martini F., Sant’antonio E., Colia M., Combi C., Levi S., Kater A.P., Hazenberg M., Nijhof I.S., Hofsink Q., Demosthenous C., Kotaskova J., Zaleska J., Vrbacky F., Raya A.M., Bisogno D., Tripoli I.E., Popov V.M., Roman V., Stavroyianni N., Karypidou M., Scarano E., Locatelli M., Frenquelli M., Scarfò L., Stamatopoulos K., Ghia P. Additional booster doses in patients with chronic lymphocytic leukemia induce humoral and cellular immune responses to SARS-CoV-2 similar to natural infection regardless ongoing treatments: A study by eric, the european research initiative on CLL. American Journal of Hematology Apr 2024, 99, 745-750, doi:10.1002/ajh.27218.

100. Ivan I.M., Popovici V., Chitescu C.L., Popescu L., Luta E.A., Ilie E.I., Brasoveanu L.I., Hotnog C.M., Olaru O.T., Nitulescu G.M., Boscencu R., Gird C.E. Phytochemical profile, antioxidant and cytotoxic potential of Capsicum annuum (L.) dry hydro-ethanolic extract. Pharmaceutics Feb 2024, 16, doi:10.3390/pharmaceutics16020245.

99. Mihai M.M., Popa M.I., Holban A.M., Gheorghe-Barbu I., Popa L.G., Chifiriuc M.C., Giurcaneanu C., Bleotu C., Cucu C.I., Lazar V. Clinical and microbiological features of host-bacterial interplay in chronic venous ulcers versus other types of chronic skin ulcers. Frontiers in Microbiology Feb 2024, 14, doi:10.3389/fmicb.2023.1326904.

98. Stecoza C.E., Nitulescu G.M., Draghici C., Caproiu M.T., Hanganu A., Olaru O.T., Mihai D.P., Bostan M., Mihaila M. Synthesis of 1,3,4-thiadiazole derivatives and their anticancer evaluation. International Journal of Molecular Sciences Dec 2023, 24, doi:10.3390/ijms242417476.

97.       Roman V., Mihaila M., Radu N., Marineata S., Diaconu C.C., Bostan M. Cell culture model evolution and its impact on improving therapy efficiency in lung cancer. Cancers Oct 2023, 15, doi:10.3390/cancers15204996.

96. Ivan B.C., Barbuceanu S.F., Hotnog C.M., Olaru O.T., Anghel A.I., Ancuceanu R.V., Mihaila M.A., Brasoveanu L.I., Shova S., Draghici C., Nitulescu G.M., Dumitrascu F. Synthesis, characterization and cytotoxic evaluation of new Pyrrolo[1,2-b]pyridazines obtained via mesoionic oxazolo-pyridazinones. Int J Mol Sci 2023, 24, doi:10.3390/ijms241411642.

95. Bolovan L.M., Ceausu M., Stanciu A.E., Panait M.E., Busca A., Hotnog C.M., Bleotu C., Gales L.N., Georgescu M.T., Prunoiu V.M., Brasoveanu L.I., Voinea S.C. Correlation studies between S100 protein level and soluble MIA or tissue MelanA and gp100 (HMB45) expression in cutaneous melanoma. J Pers Med 2023, 13, doi:10.3390/jpm13060898.

94. Iordache T.A., Badea N., Mihaila M., Crisan S., Pop A.L., Lacatusu I. Polygonum cuspidatum loaded nanostructured lipid carriers for dual inhibition of TNF-alpha- and IL-6 cytokines and free radical species. Materials (Basel) 2023, 16, doi:10.3390/ma16093492.

93. Tincu R., Mihaila M., Bostan M., Teodorescu F., Istrati D., Badea N., Lacatusu I. Novel bovine serum albumin-decorated-nanostructured lipid carriers able to modulate apoptosis and cell-cycle response in ovarian, breast, and colon tumoral cells. Pharmaceutics 2023, 15, doi:10.3390/pharmaceutics15041125.

92.      Stoica S.I., Onose G., Pitica I.M., Neagu A.I., Ion G., Matei L., Dragu L.D., Radu L.-E., Chivu-Economescu M., Necula L.G. Molecular Aspects of Hypoxic Stress Effects in Chronic Ethanol Exposure of Neuronal Cells. Current Issues in Molecular Biology 2023, 45, 1655-1680.

91.      Babeanu N., Radu N., Enascuta C.E., Alexandrescu E., Ganciarov M., Mohammed M.S.O., Suica-Bunghez I.R., Senin R., Ursu M., Bostan M. Obtaining and Characterizing Composite Biomaterials of Animal Resources with Potential Applications in Regenerative Medicine. Polymers 2022, 14, doi:10.3390/polym14173544.

90.      Zaharie M.G.O., Radu N., Pirvu L., Bostan M., Voicescu M., Begea M., Constantin M., Voaides C., Babeanu N., Roman V. Studies Regarding the Pharmaceutical Potential of Derivative Products from Plantain. Plants-Basel 2022, 11, doi:10.3390/plants11141827.

89.      Botezatu A., Fudulu A., Iancu I.V., Bostan M., Mihaila M., Albulescu A., Diaconu C.C., Anton G., Plesa A. Assessment of HPV16 viral oncogenes’ role in genome-wide pattern deposition of MBD2/3 components of NuRD nucleosome remodeling complex. Febs Open Bio 2022, 12, 164-164.

88.      Albulescu A., Fudulu A., Botezatu A., Iancu I.V., Plesa A., Brasoveanu L.I. Long noncoding RNA profile in neuroblastoma and glioblastoma. Febs Open Bio 2022, 12, 83-84.

87.      Schroder V., Radu N., Cornea P.C., Coman O.A., Pirvu L.C., Mohammed M.S.O., Stefaniu A., Pintilie L., Bostan M., Caramihai M.D., Roman V. Studies Regarding the Antimicrobial Behavior of Clotrimazole and Limonene. Antibiotics-Basel 2022, 11, doi:10.3390/antibiotics11121816.

86.      Maciuca A.M., Munteanu A.C., Mihaila M., Badea M., Olar R., Nitulescu G.M., Munteanu C.V.A., Uivarosi V. A Study on Repositioning Nalidixic Acid via Lanthanide Complexation: Synthesis, Characterization, Cytotoxicity and DNA/Protein Binding Studies. Pharmaceuticals 2022, 15, doi:10.3390/ph15081010.

85.      Ivan B.C., Barbuceanu S.F., Hotnog C.M., Anghel A.I., Ancuceanu R.V., Mihaila M.A., Brasoveanu L.I., Shova S., Draghici C., Olaru O.T., Nitulescu G.M., Dinu M., Dumitrascu F. New Pyrrole Derivatives as Promising Biological Agents: Design, Synthesis, Characterization, In Silico, and Cytotoxicity Evaluation. International Journal of Molecular Sciences 2022, 23, doi:10.3390/ijms23168854.

84.      Botezatu A., Plesa A., Iancu I.V., Bostan M., Mihaila M., Albulescu A., Fudulu A., Diaconu C.C., Anton G. E6 and E7 HPV16 oncogenes influence gene transcription trough the genome-wide pattern deposition of MBD2, 3 components of NuRD nucleosome remodeling complex. In Proceedings of the EUROPEAN JOURNAL OF HUMAN GENETICS, 2022; pp. 542-542.

83.      Mihaila M., Hotnog C.M., Bostan M., Munteanu A.C., Vacaroiu I.A., Brasoveanu L.I., Uivarosi V. Anticancer Activity of Some Ruthenium(III) Complexes with Quinolone Antibiotics: In Vitro Cytotoxicity, Cell Cycle Modulation, and Apoptosis-Inducing Properties in LoVo Colon Cancer Cell Line. Applied Sciences-Basel 2021, 11, doi:10.3390/app11188594.

82.      Lacatusu I., Iordache T.A., Mihaila M., Mihaiescu D.E., Pop A.L., Badea N. Multifaced Role of Dual Herbal Principles Loaded-Lipid Nanocarriers in Providing High Therapeutic Efficacity. Pharmaceutics 2021, 13, doi:10.3390/pharmaceutics13091511.

81.      Ion G., Akinsete J.A., Witte T.R., Bostan M., Hardman W.E. Maternal fish oil consumption has a negative impact on mammary gland tumorigenesis in C3(1) Tag mice offspring. European Journal of Nutrition 2021, 60, 3771-3781, doi:10.1007/s00394-021-02546-8.

80.      Dumitru M., Mihaila M., Hotnog C.M., Panait M.E., Vasilescu M.M., Hortopan M.G., Brasoveanu L.I. HER2 expression in primary bladder tumors and paired regional lymph nodes: Relationship to cell cycle profile. Annals of Oncology 2021, 32, S1369-S1370, doi:10.1016/j.annonc.2021.08.2076.

79.      Iordache T.A., Badea N., Mihaila M., Crisan S., Pop A.L., Lacatusu I. Challenges in Coopted Hydrophilic and Lipophilic Herbal Bioactives in the Same Nanostructured Carriers for Effective Bioavailability and Anti-Inflammatory Action. Nanomaterials 2021, 11, doi:10.3390/nano11113035.

78.      Stecoza C.E., Nitulescu G.M., Draghici C., Caproiu M.T., Olaru O.T., Bostan M., Mihaila M. Synthesis and Anticancer Evaluation of New 1,3,4-Oxadiazole Derivatives. Pharmaceuticals 2021, 14, doi:10.3390/ph14050438.

77.      Bostan M., Mihaila M., Petrica-Matei G.G., Radu N., Hainarosie R., Stefanescu C.D., Roman V., Diaconu C.C. Resveratrol Modulation of Apoptosis and Cell Cycle Response to Cisplatin in Head and Neck Cancer Cell Lines. International Journal of Molecular Sciences 2021, 22, doi:10.3390/ijms22126322.

76.      Munteanu A.C., Musat M.G., Mihaila M., Badea M., Olar R., Nitulescu G.M., Radulescu F.S., Brasoveanu L.I., Uivarosi V. New heteroleptic lanthanide complexes as multimodal drugs: Cytotoxicity studies, apoptosis, cell cycle analysis, DNA interactions, and protein binding. Applied Organometallic Chemistry 2021, 35, doi:10.1002/aoc.6062.

75.      Ioan D.C., Rau I., Kaya M.G.A., Radu N., Bostan M., Zgarian R.G., Tihan G.T., Dinu-Pirvu C.E., Lupuliasa A., Ghica M.V. Ciprofloxacin-Collagen-Based Materials with Potential Oral Surgical Applications. Polymers 2020, 12, doi:10.3390/polym12091915.

74.      Bostan M., Petrica-Matei G.G., Radu N., Hainarosie R., Stefanescu C.D., Diaconu C.C., Roman V. The Effect of Resveratrol or Curcumin on Head and Neck Cancer Cells Sensitivity to the Cytotoxic Effects of Cisplatin. Nutrients 2020, 12, doi:10.3390/nu12092596.

73.      Maciuca A.M., Munteanu A.C., Mihaila M., Badea M., Olar R., Nitulescu G.M., Munteanu C.V.A., Bostan M., Uivarosi V. Rare-Earth Metal Complexes of the Antibacterial Drug Oxolinic Acid: Synthesis, Characterization, DNA/Protein Binding and Cytotoxicity Studies. Molecules 2020, 25, doi:10.3390/molecules25225418.

72.      Neagu A.I., Mambet C., Necula L.G., Matei L., Dragu D.L., Ataman M., Petrica-Matei G.G., Alexiu I., Nedeianu S., Bleotu C., Stoian M., Diaconu C.C. Therapeutic potential of T regulatory cell manipulation: advantages and limitations. Romanian Biotechnological Letters 2020, 25, 1501-1510, doi:10.25083/rbl/25.2/1501.1510.

71.      Radu N., Chirvase A.A., Babeanu N., Popa O., Cornea P., Pirvu L., Bostan M., Ciric A., Mathe E., Radu E., Doni M., Constantin M., Raut I., Gurban A.M., Begea M. Study Regarding the Potential Use of a Spent Microbial Biomass in Fertilizer Manufacturing. Agronomy-Basel 2020, 10, doi:10.3390/agronomy10020299.

70.      Iancu I.V., Botezatu A., Plesa A., Huica I., Fudulu A., Albulescu A., Bostan M., Mihaila M., Grance C., Manda D.A., Dobrescu R., Vladoiu S.V., Anton G., Badiu C.V. Alterations of regulatory factors and DNA methylation pattern in thyroid cancer. Cancer Biomarkers 2020, 28, 255-268, doi:10.3233/cbm-190871.

69.      Dumitru M., Gruia M.I., Botezatu A., Mihaila M., Hotnog C.M., Hortopan M., Panait M.E., Anton G., Brasoveanu L.I. HER2 Ile655Val polymorphism, EGFR expression and cellular proliferation in urinary bladder carcinomas. Annals of Oncology 2019, 30, doi:10.1093/annonc/mdz413.078.

68.      Ciulu-Costinescu F., Podgoreanu P., Delcaru C., Simionescu A., Georgescu E.F., Bostan M., Chifiriuc M.C. ANTIMICROBIAL ASSAY OF A CAPSAICIN – alpha-CYCLODEXTRIN INCLUSION COMPLEX AGAINST PLANKTONIC AND ADHERENT CELLS. Farmacia 2019, 67, 496-503, doi:10.31925/farmacia.2019.3.18.

67.      Hotnog C.M., Mihaila M., Puiu L., Botezatu A., Roman V., Popescu I.D., Bostan M., Brasoveanu L.I. Modulation of the interplay between p53, ICAM-1 and VEGF in drug-treated LoVo colon cancer cells. Romanian Biotechnological Letters 2019, 24, 261-270, doi:10.25083/rbl/24.2/261.270.

66.      Lacatusu I., Badea N., Badea G., Mihaila M., Ott C., Stan R., Meghea A. Advanced bioactive lipid nanocarriers loaded with natural and synthetic anti-inflammatory actives. Chemical Engineering Science 2019, 200, 113-126, doi:10.1016/j.ces.2019.01.044.

65.      Ciocilteu M.V., Podgoreanu P., Delcaru C., Chifiriuc M.C., Manda C.V., Bita A., Popescu M., Amzoiu E., Croitoru O., Bleotu C., Bostan M., Neamtu J. PLGA-GENTAMICIN BIOCOMPOSITE MATERIALS WITH POTENTIAL ANTIMICROBIAL APPLICATIONS IN ORTHOPEDICS. Farmacia 2019, 67, 580-586, doi:10.31925/farmacia.2019.4.4.

64.      Albulescu A., Diaconu C.C., Fudulu A., Iancu I.V., Botezatu A., Plesa A., Huica I., Socolov D., Brasoveanu I., Anton G. hADA3 mutations in acquisition of hrHPV infection. Febs Open Bio 2019, 9, 159-160.

63.      Petrica-Matei G.G., Roman V., Mihaila M., Hotnog C.M., Brasoveanu L.I., Bostan M. Role of p38-mitogen-activated protein kinase in modulation of the response to therapy in FaDu Human pharyngeal carcinoma cell. Romanian Biotechnological Letters 2019, 24, 118-128, doi:10.25083/rbl/24.1/118.128.

62.      Roman V., Radu N., Bostan M., Popa O., Tanasescu C.a.H. Effect of Melaleuca alternifolia bioproduct on acute monocytic leukemia cells line. Molecular Crystals and Liquid Crystals 2019, 695, 29-36, doi:10.1080/15421406.2020.1723903.

61.      Bostan M., Radu N., Babeanu N., Zaharie M.G., Tanasescu C.a.H. Biological properties of a biomaterial obtained from Syzygium aromaticum. Molecular Crystals and Liquid Crystals 2019, 695, 45-52, doi:10.1080/15421406.2020.1723905.

60.      Bostan M., Petrica-Matei G.G., Ion G., Radu N., Mihaila M., Hainarosie R., Brasoveanu L.I., Roman V., Constantin C., Neagu M.T. Cisplatin effect on head and neck squamous cell carcinoma cells is modulated by ERK1/2 protein kinases. Experimental and Therapeutic Medicine 2019, 18, 5041-5051, doi:10.3892/etm.2019.8139.

59.      Neagu M., Constantin C., Bostan M., Caruntu C., Ignat S.R., Dinescu S., Costache M. Proteomic technology “lens” for epithelial-mesenchymal transition process identification in oncology. Analytical Cellular Pathology 2019, 2019.

58.      Caramihai M., Radu N., Bostan M., Ion G., Chirvase A., Constantin M., Doni M., Babeanu N. Fuzzy predictions regarding in vitro behavior of cells line under cytostatic treatment. In Proceedings of the 2019 E-Health and Bioengineering Conference (EHB), 2019; pp. 1-5.

57.      Botezatu A., Iancu I.V., Plesa A., Manda D., Popa O., Bostan M., Mihaila M., Albulescu A., Fudulu A., Vladoiu S.V., Huica I., Dobrescu R., Anton G., Badiu C. Methylation of tumour suppressor genes associated with thyroid cancer. Cancer Biomarkers 2019, 25, 53-65, doi:10.3233/cbm-182265.

56.      Murarasu D., Puiu L., Mihalcea C.E., Pitica I.M.A., Mambet C., Radu E.L., Matei L., Dragu D.L., Simion L., Marincas M.A., Chivu-Economescu M., Cinca S., Brasoveanu L., Bleotu C., Diaconu C.C. Characterization of TP53 polymorphisms in Romanian colorectal cancer patients. Romanian Biotechnological Letters 2018, 23, 14124-14134, doi:10.26327/rbl2017.04.

55.      Murarasu D., Puiu L., Pitica I.M.A., Mambet C., Mihalcea C.E., Marincas A.M., Cinca S., Brasoveanu L., Diaconu C.C. TP53 somatic mutations and LOH profile in colorectal cancer in Romania. Romanian Biotechnological Letters 2018, 23, 13530-13540.

54.      Diaconu C.C., Mambet C., Necula L.G., Gurban P., Matei L., Aldea-Pitica I.M., Neagu A.I., Botezatu A., Bleotu C., Chivu-Economescu M., Roman V., Coriu D., Constantinescu S. Triple Negative Myeloproliferative Neoplasms – Sometimes Driver Mutations Stay Low-Key in Plain Sight. Romanian Biotechnological Letters 2018, 23, 13750-13760, doi:10.26327/rbl2017.12.

53.      Munteanu A.C., Badea M., Olar R., Silvestro L., Mihaila M., Brasoveanu L.I., Musat M.G., Andries A., Uivarosi V. Cytotoxicity studies, DNA interaction and protein binding of new Al (III), Ga (III) and In (III) complexes with 5-hydroxyflavone. Applied Organometallic Chemistry 2018, 32, doi:10.1002/aoc.4579.

52.      Badea G., Badea N., Brasoveanu L.I., Mihaila M., Stan R., Istrati D., Balaci T., Lacatusu I. Naringenin improves the sunscreen performance of vegetable nanocarriers. New Journal of Chemistry 2017, 41, 480-492, doi:10.1039/c6nj02318e.

51.      Radu N., Roman V., Bostan M., Voicescu M., Tanasescu C. Bioproduct obtained from probiotic microorganisms consortia-studies regarding the effects generated in vitro on two types of leukemic cell lines. Molecular Crystals and Liquid Crystals 2017, 655, 275-286, doi:10.1080/15421406.2017.1362311.

50.      Radu N., Roman V., Bostan M., Voicescu M., Tanasescu C. Effects of biomaterials obtained from consortia of probiotic microorganism in submerged biosynthesis on THP1 cells line. Molecular Crystals and Liquid Crystals 2017, 655, 255-265.

49.      Radu N., Roman V., Bostan M., Radu E., Tanasescu C. Influence of some spice food based bioproducts on human monocytic cells line type THP-1. Molecular Crystals and Liquid Crystals 2017, 655, 114-123.

48.      Lixandru D., Alexandru P., Mihai A., Rosca A., Ionescu-Tirgoviste C., Brasoveanu L.I., Manuel-Y-Keenoy B. Decreased paraoxonase 2 enzymatic activity in monocyte/macrophages cells. A comparative in vivo and in vitro study for diabetes. Free Radical Research 2017, 51, 604-615, doi:10.1080/10715762.2017.1344983.

47.      Radu N., Roman V., Tanasescu C. Biomaterials obtained from probiotic consortia of microorganisms. Potential applications in regenerative medicine. Molecular Crystals and Liquid Crystals 2016, 628, 115-123, doi:10.1080/15421406.2015.1137686.

46.      Petrica-Matei G.G., Iordache F., Hainarosie R., Bostan M. Characterization of the tumor cells from human head and neck cancer. Romanian Journal of Morphology and Embryology 2016, 57, 791-799.

45.      Lacatusu I., Badea N., Badea G., Brasoveanu L., Stan R., Ott C., Oprea O., Meghea A. Ivy leaves extract based – lipid nanocarriers and their bioefficacy on antioxidant and antitumor activities. Rsc Advances 2016, 6, 77243-77255, doi:10.1039/c6ra12016d.

44.      Bostan M., Mihaila M., Hotnog C., Bleotu C., Anton G., Roman V., Brasoveanu L.I. Modulation of Apoptosis in Colon Cancer Cells by Bioactive Compounds; 2016; pp. 51-87.

43.      Lacatusu I., Badea N., Badea G., Oprea O., Mihaila M.A., Kaya D.A., Stan R., Meghea A. Lipid nanocarriers based on natural oils with high activity against oxygen free radicals and tumor cell proliferation. Materials Science & Engineering C-Materials for Biological Applications 2015, 56, 88-94, doi:10.1016/j.msec.2015.06.019.

42.      Hotnog D., Mihaila M., Botezatu A., Matei G.G., Hotnog C., Anton G., Bostan M., Brasoveanu L.I. GENISTEIN POTENTIATES THE APOPTOTIC EFFECT OF 5-FLUOROURACYL IN COLON CANCER CELL LINES. Romanian Biotechnological Letters 2013, 18, 8751-8760.

41.      Mihaila M., Bostan M., Hotnog D., Ferdes M., Brasoveanu L.I. REAL-TIME ANALYSIS OF QUERCETIN, RESVERATROL AND/OR DOXORUBICIN EFFECTS IN MCF-7 CELLS. Romanian Biotechnological Letters 2013, 18, 8106-8114.

40.      Dumitru M., Gruia M.I., Hortopan M.G., Vasilescu M.M., Mihaila M., Hotnog C.M., Brasoveanu L.I. HER2 gene amplification, phosphorylated-HER2, EGFR expression and DNA ploidy in urinary bladder carcinomas. Febs Journal 2012, 279, 319-320.

39.      Iova A., Bumbea H., Roman V., Vladareanu A.M., Cazaceanu O., Enache C., Begu M. CD200 IN DIAGNOSIS OF CHRONIC LYMPHOPROLIFERATIVE DISORDERS- A STUDY OF 122 PATIENTS. Haematologica 2012, 97, 298-298.

38.      Brasoveanu L.I., Hotnog D., Hotnog C., Bostan M., Mihaila M. Modulation of Genistein- and Resveratrol-induced Apoptosis and Cell Proliferation in Colon Cancer Cells. European Journal of Cancer 2012, 48, S267-S268, doi:10.1016/s0959-8049(12)71713-6.

37.      Mihaila M., Hotnog C., Dina I., Hotnog D., Brasoveanu L.I. Modulation of cell signalling mechanisms in colon cancer cells. Febs Journal 2011, 278, 362-362.

36.      Brasoveanu L.I., Mihaila M., Dina I., Hotnog C., Puiu L. p53 and apoptosis could be modulated by natural compounds in colon cancer cells. Febs Journal 2011, 278, 344-344.

35.      Mihaila M., Hotnog C., Theodor V., Brasoveanu L.I. Effect of Stimuli Treatment on Cell Signalling Mechanisms Associated to Oral Cancers. Scandinavian Journal of Immunology 2010, 71, 502-502.

34.      Mihaila M., Hotnog C., Theodor V., Brasoveanu L. Effect of stimuli treatment on proliferation, apoptosis and cell signalling mechanisms associated to oral cancers. Ejc Supplements 2010, 8, 80-80, doi:10.1016/s1359-6349(10)71115-0.

33.      Hotnog D., Roman V. Mitochondrial apoptotic molecules and genistein. Ejc Supplements 2010, 8, 198-199, doi:10.1016/s1359-6349(10)71585-8.

32.      Hotnog C., Mihaila M., Brasoveanu L.I. Gene expression analysis of tumour markers associated to apoptosis and proliferation in head and neck cancer. Ejc Supplements 2010, 8, 80-80, doi:10.1016/s1359-6349(10)71113-7.

31.      Bumbea H., Vladareanu A.M., Radesi S., Vintilescu A., Roman V., Ciufu C., Hotnog D., Arama V., Onisai M., Popov V.M., Baluta C., Cazaceanu O., Voican I., Cisleanu D., Marinescu C., Arama S., Rafila A., Streinu-Cercel A., Nicolescu A., Gaman M., Ichim A., Begu M. VIRAL INFECTIOUS IN CHRONIC LYMPHOPROLIFERATIVE DISORDERS-IMMUNOPHENOTYPIC CHANGES. Haematologica-the Hematology Journal 2010, 95, 612-612.

30.      Brasoveanu L.I., Hotnog C., Mihaila M., Puiu L. Expression of cell adhesion molecules on MDR-1 positive stimuli treated breast tumour cells. Ejc Supplements 2010, 8, 80-80, doi:10.1016/s1359-6349(10)71114-9.

29.      Bostan M., Matei G.G., Manu D., Brasoveanu L.I. Induction of Apoptosis by Cisplatin and its Effect on Cell Cycle Changes in Laryngeal Cancer. Scandinavian Journal of Immunology 2010, 71, 500-501.

28.      Anton G., Brasoveanu L.I., Socolov D., Botezatu A., Anton M., Goia C.D., Iancu I.V., Cucu N. Epigenetic regulation to anti-cancer drugs in HPV positive cell lines. Ejc Supplements 2010, 8, 72-73, doi:10.1016/s1359-6349(10)71083-1.

27.      Hirt M., Hotnog D., Hotnog C., Puil L., Brasoveanu L.I. Effect of stimuli treatment on cell signalling mechanisms associated to colorectal cell lines. In Proceedings of the 2nd European Congress of Immunology (ECI), Berlin, GERMANY, Sep 13-16, 2009; pp. 391-+.

26.      Brasoveann L.L., Hirt M., Matel G., Bostan M., Puiu L. Stimuli modulation of apoptosis and proliferation through cell cycle phases hi colon cancer cell lines. In Proceedings of the 2nd European Congress of Immunology (ECI), Berlin, GERMANY, Sep 13-16, 2009; pp. 127-+.

25.      Bostan M., Matei G.G., Manu D.A., Theodor V., Brasoveanu L.I. Analysis of the effects after resveratrol treatment on cell cycle and apoptosis in tumor laryngeal cells. In Proceedings of the 2nd European Congress of Immunology (ECI), Berlin, GERMANY, Sep 13-16, 2009; pp. 387-+.

24.      Niculae D., Lungu V., Brasoveanu L., Savu D., Iliescu M. IN VITRO BIOLOGICAL EVALUATION OF (RE)-R-188-ANTI-VEGF-MAB AND (RE)-R-188-ANTI-MUC1. Journal of Labelled Compounds & Radiopharmaceuticals 2009, 52, 258-259.

23.      Bumbea H., Radesi S., Vladareanu A.M., Roman V., Vintilescu A. Complex Immunophenotypic Changes as Prognosis Panel in Chronic Lymphocytic Leukemia. Clinical Lymphoma & Myeloma 2009, 9, E37-E37, doi:10.3816/CLM.2009.n.099.


21.      Hirt M., Hotnog C., Cimpean A., Puiu L., Brasoveanu L.I. Modulation by oncolitical treatment associated with natural compounds on proliferation and apoptosis of breast tumor cells. Febs Journal 2008, 275, 259-259.

20.      Brasoveanu L.I., Hirt M., Hotnog C., Gruia M.I., Puiu L. Biomarkers in radioimmunotherapy of breast and ovarian cancers. Febs Journal 2008, 275, 257-257.

19.      Roman V., Hotnog D., Maglas C., Brasoveanu L.I. Effects of mycotoxins on apoptosis of human immune system. Ejc Supplements 2008, 6, 136-136, doi:10.1016/s1359-6349(08)71696-3.

18.      Lixandru D., Heytens E., Brasoveanu L.I., Manuel-Y-Keenoy B. Triglyceride rich lipoproteins reverse the alterations in respiratory burst and PON2 activity in serum-deprived cells from the monocyte line U937. Free Radical Research 2008, 42, S76-S76.

17.      Brasoveanu L.I., Hotnog C., Roman V., Hirt M., Bostan M., Cinca S., Puiu L. Effect of stimuli treatment on proliferation and apoptosis of tumor cells. Ejc Supplements 2008, 6, 136-136, doi:10.1016/s1359-6349(08)71698-7.

16.      Ionesti M.C., Matei G., Hirt M., Bostan M., Puiu L., Brasoveanu L.I. Correlation analysis between expression and functional roles of CAM on doxorubicin treated tumor cells. Febs Journal 2007, 274, 264-264.

15.      Hotnog D., Brasoveanu L.I., Ionesti C.M., Roman V. Role of flavonoids in cancer immunotherapy. Febs Journal 2007, 274, 159-159.

14.      Brasoveanu L.I., Ionesti M.C., Hotnog D., Hirt M., Bostan M., Puiu L. Modulation by stimuli treatment of proliferation, cell cycle phases and apoptosis of tumor cells. Febs Journal 2007, 274, 177-177.

13.      Hotnog D., Roman V., Brasoveanu L.I., Billard C., Kolb J.P. Resveratrol and mitochondrial pathway of apoptosis. Febs Journal 2006, 273, 125-125.

12.      Brasoveanu L.I., Hotnog D., Simioana M.D., Puiu L., Constantin M.C. Tumor markers of potential clinical use in radioimmunotherapy. Febs Journal 2006, 273, 276-276.

11.      Puiu L., Constantin M.C., Simioana M.D., Hotnog D., Diaconu C.C., Brasoveanu L.I. MODULATION OF DRUG-INDUCED APOPTOSIS IN BREAST CANCER CELL LINES. Anticancer Research 2004, 24, 3607-3608.

10.      Brasoveanu L.I., Simioana M.D., Hotnog D., Puiu L., Condrea I., Constantin M.C., Gruia M.I. MECHANISMS OF TUMOR RESISTANCE TO ANTI-MUC-1 TREATMENT INVOLVING COMPLEMENT REGULATORY PROTEINS. Anticancer Research 2004, 24, 3443-3444.

9.         Mota G., Moldovan I., Calugaru A., Hirt M., Kozma E., Galatiuc C., Brasoveanu L., Boltz-Nitulescu G. Interaction of human immunoglobulin G with CD16 on natural killer cells: Ligand clearance, Fc gamma RIIIA turnover and effects of metalloproteinases on Fc gamma RIIIA-mediated binding, signal transduction and killing. Scandinavian Journal of Immunology 2004, 59, 278-284, doi:10.1111/j.0300-9475.2004.01398.x.

8.         Chivu M., Diaconu C.C., Bleotu C., Alexiu I., Brasoveanu L., Cernescu C. The comparison of different protocols for expansion of umbilical-cord blood hematopoietic stem cells. Journal of Cellular and Molecular Medicine 2004, 8, 223-231, doi:10.1111/j.1582-4934.2004.tb00277.x.

7.         Bostan M., Galatiuc C., Hirt M., Constantin M.C., Brasoveanu L.I., Iordachescu D. Phospholipase A(2) modulates respiratory burst developed by neutrophils in patients with rheumatoid arthritis. Journal of Cellular and Molecular Medicine 2003, 7, 57-66, doi:10.1111/j.1582-4934.2003.tb00203.x.

6.         Mota G., Manciulea M., Cosma E., Popescu I., Hirt M., Jensen-Jarolim E., Calugaru A., Galatiuc C., Regalia T., Tamandl D., Spittler A., Boltz-Nitulescu G. Human NK cells express Fc receptors for IgA which mediate signal transduction and target cell killing. European Journal of Immunology 2003, 33, 2197-2205, doi:10.1002/eji.200323534.

5.         Chivu M., Diaconu C.C., Brasoveanu L., Alexiu I., Bleotu C., Banceanu G., Miscalencu D., Cernescu C. Ex vivo differentiation of umbilical cord blood progenitor cells in the presence of placental conditioned medium. Journal of Cellular and Molecular Medicine 2002, 6, 609-619, doi:10.1111/j.1582-4934.2002.tb00459.x.

4.         Bostan M., Brasoveanu L.I., Livescu A., Manda G., Neagu M., Iordachescu D. Effects of synovial fluid on the respiratory burst of granulocytes in rheumatoid arthritis. Journal of Cellular and Molecular Medicine 2001, 5, 188-194, doi:10.1111/j.1582-4934.2001.tb00152.x.

3.         Roman V., Mentz F., Dugas N., Dugas B., Sigaux F., Kolb J.P. Apoptotic process modulated by nitric oxide in chronic B-cell lymphocytic leukemia. In Proceedings of the Conference of the NATO Advanced Study Institute on Nitric Oxide, Erice, Italy, Sep 07-17, 2000; pp. 188-189.

2.         Popescu I., Hirt M., Calugaru A., Balu D., Manciulea M., Metes D., Morel P., Herberman R., Sulica A. Cross-talk between c gamma RIIA, and c gamma RIIc an human natural killer cells. European Journal of Cancer 1999, 35, S106-S106, doi:10.1016/s0959-8049(99)80805-3.

1.         Hirt M., Cheta D., Popescu I., Sulica A., Manciulea M. Changes in Fc gamma RIIIA signalling