ACTION 1.1.4 Attracting high-level personnel from abroad in order to enhance the RD capacity
Project title: Molecular Profiling of Myeloproliferative Neoplasms and Acute Myeloid Leukemia for Designing Early Diagnostic, Prognostic and Treatment Strategies (MYELOAL – EDIAPROT)
ID / Cod My SMIS: P 37_798/106774
Contract No: 149/26.10.2016
RELEVANT RESULTS
(2018)
Proposals for new projects or integrations into existing networks:
- Horizon 2020 – H2020 –JTI-IMI-2017-13-two-stage /Topic: IMI2-2017-13-08: Type: IMI-RIA
The Cancer Precision Immunotherapy Directory
Proposal ID: 821540-1
Acronym: CAPSID
Coordinator stiintific: Prof. Dr. George Collias, Biomedical Sciences Research Center ‘Alexander Fleming’, Athens, Greece - Horizon 2020 – H2020-INFRAEOSC-2018-2020 (Implementing the European Open Science Cloud) with theme INFRAEOSC-05-2018-2019, CSA type
Health EOSC Coordination Tractioning Oncology Research – HECTOR”,
Proposal ID: SEP-201519874
Acronym DRUGMEDIK,
Coordinator Prof. Ivan Ivanov , University of Chemical Technology SOFIA, BG. - Horizon 2020 – H2020 – H2020-SU-SEC-2018-2019-2020; SU-DRS-05-2019 (contracted)
Demonstration of intelligent decision support for pandemic crisis prediction and management within and across European borders
Acronym: STAMINA
Proposal ID: 883441
Coordinator: EXUS Software LLc - EU-Horizon 2020: FETOPEN-01-2018-2019-2020/ RIA
Enlarging cancer research knowledge and medication-Discovery of novel drugs and novel targets for cancer therapy
Acronym: ECARKOM
Proposal ID 964336
Coordinator: Prof. Ivan Ivanov , University of Chemical Technology SOFIA, BG
Scientific publications:
Phenotypic Screening. Methods in Molecular Biology, vol 1787. pp53-66, Humana Press, New York, Springer Print ISBN NY978-1-4939-7846-5, On line ISBN: 978-1-4939-7847-2, Wagner B. (eds); 2018 DOI 10.2174/1386207319666161010163825; Phenotypic Screening for Inhibitors of a Mutant Thrombopoietin Receptor. Anna Ngo, Ann Koay, Christian Pecquet, Carmen C Diaconu, David A Jenkins, Andrew K Shiau, Stefan N Constantinescu, Meng Ling Choong.
Journal of Cellular and Molecular Medicine, 2018, 22(8), 4005-4011, (Web of Science/ISI IF 4,658) DOI:10.1111/jcmm.13753; Increased Dkk-1 Plasma Levels May Discriminate Disease Subtypes in Myeloproliferative Neoplasms, Cristina Mambet, Laura Necula, Simona Mihai, Lilia Matei, Coralia Bleotu, Mihaela Chivu-Economescu, Oana Stanca, Aurelia Tatic, Nicoleta Berbec, Cristiana Tanase, Carmen C. Diaconu.
World Journal of Stem Cells, Jun 26, 2018; 10(6): pg. 57-65, (Web of Science/ISI IF 5,614). DOI: 10.4252/wjsc.v10.i6.57; Murine models based on acute myeloid leukemia-initiating stem cells xenografting, Cristina Mambet, Mihaela Chivu-Economescu, Lilia Matei, Laura Georgiana Necula, Denisa Laura Dragu, Coralia Bleotu, Carmen Cristina Diaconu.
Blood, 132:Suppl 1: 3066, 2018, (Web of Science/ISI IF 16,562) doi: https://doi.org/10.1182/blood-2018-99-117019); JAK2 R1063H Variant Enhances V617F Constitutive Signaling and Favors Development of Essential Thrombocythemia with Increased Hemoglobin and Neutrophils, Cristina Mambet, Jean-Philippe Defour, Olga Babosova, Emilie Leroy, Laura Necula, Oana Stanca, Aurelia Tatic, Nicoleta Berbec, Daniel Coriu, Monika Belickova, Barbora Kralova, Lucie Lanikova, Pascale Saussoy, Violaine Havelange, Carmen C. Diaconu, Vladimir Divoky and Stefan N. Constantinescu
Blood 132 (25): 2695 – 2699, 2018, (Web of Science/ISI IF 16,562); publicat pe 30 octombrie 2018, doi:10.1182/blood-2018-04-843060; Co-occurring JAK2 V617F and R1063H mutations increase JAK2 signaling and neutrophilia in myeloproliferative neoplasms, Cristina Mambet, Olga Babosova, Jean-Philippe Defour, Emilie Leroy, Laura Necula, Oana Stanca, Aurelia Tatic, Nicoleta Berbec, Daniel Coriu, Monika Belickova, Barbora Kralova, Lucie Lanikova, Jitka Vesela, Christian Pecquet, Pascale Saussoy, Violaine Havelange, Carmen C. Diaconu, Vladimir Divoky and Stefan N. Constantinescu.
Scientific public-private co-publications:
Romanian Biotechnological Letters 2018, 23, 13750-13760, doi:10.26327/rbl2017.12. Triple Negative Myeloproliferative Neoplasms – Sometimes Driver Mutations Stay Low-Key in Plain Sight, Carmen C. Diaconu, Cristina Mambet, Laura G. Necula, Petruta Gurban, Lilia Matei, Ioana M. Aldea-Pitica, Ana I. Neagu, Anca Botezatu, Coralia Bleotu, Mihaela Chivu-Economescu, Viviana Roman, Daniel Coriu, Stefan Constantinescu.
Equipment purchases:
Real-time PCR platform
Protein multiplex platform
