Cellular and Molecular Pathology

Our objectives reflect a comprehensive approach to medical research and disease management. By delving into the molecular and physiological mechanisms involved in disease and infection control, we can better understand how to specifically target the underlying causes of these conditions

Our objectives reflect a comprehensive approach to medical research and disease management. By delving into the molecular and physiological mechanisms involved in disease and infection control, we can better understand how to specifically target the underlying causes of these conditions. This knowledge can then be applied to identify genes or genetic expressions that could be useful in managing a range of therapies and conditions, including antiviral, anticancer, post-transplant, and psychiatric therapies. Genotyping allows us to identify patient subsets that could benefit from these therapies, which can be particularly useful in designing clinical trials or drug rescue programs. Additionally, by evaluating new and improved drug and drug target options, we can develop more effective treatments and bring innovative therapies to market.

The use of stem cell technology is another area of focus, particularly in implementing cell therapy procedures for patients suffering from malignant disorders, hepatic failure, and inborn congenital disorders. By harnessing stem cells’ regenerative potential, we can improve patient outcomes and provide more effective treatment options.

Overall, our objectives reflect a commitment to advancing medical research and improving patient care. By taking a multifaceted approach to disease management, we can make significant strides in developing new biomarkers for diagnosis and progression, new therapies, and improving existing treatments.

Expertise area includes molecular genetics, cellular and molecular pathology, multidrug resistance, interaction between host neuroimmune
Expertise area includes host-microbe interaction, tumor cell biology (signal transduction, epigenetic mechanisms, targeted anti-tumor and
Expertise area includes cancer cell signaling, targeted anti-cancer therapy, and immunotherapy.
FLORICA TOPÂRCEANU is senior researcher II at Cellular and Molecular Pathology Department. Expertise area includes
LILIA MATEI is senior researcher II at Cellular and Molecular Pathology Department. Expertise area includes
LAURA-DENISA DRAGU, is senior researcher II at Cellular and Molecular Pathology Department. Expertise area includes
ANA-IULIA NEAGU is scientific researcher III at Cellular and Molecular Pathology Department. Expertise area includes
CRISTINA MAMBET is a scientific researcher III at Cellular and Molecular Pathology Department. Expertise area
IOANA ALDEA-PITICA is scientific researcher III at Cellular and Molecular Pathology Department. Expertise includes cell
SAVIANA NEDEIANU is scientific researcher III at Cellular and Molecular Pathology Department. Expertise includes cell
ALINA SCHULMAN is scientific researcher III at Cellular and Molecular Pathology Department. Expertise includes immunofluorescence
MARIUS ATAMAN is researcher at Cellular and Molecular Pathology Department. Research interests: (1) Studies on
ELENA RADU is junior researcher at Cellular and Molecular Pathology Department. Expertise area includes antibiotic
Stoica S.I., Onose G., Pitica I.M., Neagu A.I., Ion G., Matei L., Dragu L.D., Radu L.-E., Chivu-Economescu M., Necula L.G. Molecular Aspects of Hypoxic Stress Effects in Chronic Ethanol Exposure of Neuronal Cells. Current Issues in Molecular Biology 2023, 45, 1655-1680.

370. Shirima C.A., Bleotu C., Spandidos D.A., El-Naggar A.K., Pircalabioru G.G., Michalopoulos I. Epithelial-derived head and neck squamous tumourigenesis (review). Oncology Reports Oct 2024, 52, doi:10.3892/or.2024.8800.

369. Gheorghe G., Diaconu C.C., Mambet C., Bleotu C., Ionescu V.A., Diaconu C.C. Comparative analysis of leptin and carcinoembryonic antigen-related cell adhesion molecule 1 plasma expression in pancreatic cancer and chronic pancreatitis patients. Heliyon Sep 2024, 10, doi:10.1016/j.heliyon.2024.e37410.

368. Olteanu A.A., Radulescu F.S., Bleotu C., Arama C.C. Development and characterization of a cyclodextrin-based delivery system for enhanced pharmacokinetic and safety profile of oseltamivir. Journal of Inclusion Phenomena and Macrocyclic Chemistry 2024 Sep 2024, doi:10.1007/s10847-024-01258-w.

367. Adesola A.A., Chen Y.F., Cozma M.A., Gaman M.A. Updates into the potential association between myeloproliferative neoplasms and inflammatory bowel disease. Journal of the Pakistan Medical Association Aug 2024, 74, 1416-1417, doi:10.47391/jpma.24-60.

366. Benali Y., Predoi D., Rokosz K., Ciobanu C.S., Iconaru S.L., Raaen S., Negrila C.C., Cimpeanu C., Trusca R., Ghegoiu L., Bleotu C., Marinas I.C., Stan M., Boughzala K. Physico-chemical properties of copper-doped hydroxyapatite coatings obtained by vacuum deposition technique. Materials Aug 2024, 17, doi:10.3390/ma17153681.

365. Gurban P., Mambet C., Botezatu A., Necula L.G., Matei L., Neagu A.I., Pitica I.M., Dragu L.D., Schulman A.N., Ataman M., Nedeianu S., Chivu-Economescu M., Bleotu C., Anton G., Diaconu C.C. Increased mRNA expression for serotonin receptor 1B (HTR1B) is associated with thrombosis in BCR::ABL1-negative myeloproliferative neoplasms. Journal of Cellular and Molecular Medicine Aug 2024, 28, doi:10.1111/jcmm.70024.

364. Bleotu C., Matei L., Dragu L.D., Necula L.G., Pitica I.M., Chivu-Economescu M., Diaconu C.C. Viruses in wastewater-a concern for public health and the environment. Microorganisms Jul 2024, 12, doi:10.3390/microorganisms12071430.

363. Grigoroiu-Serbanescu M., Van Der Veen T., Bigdeli T., Herms S., Diaconu C.C., Neagu A.I., Bass N., Thygesen J., Forstner A.J., Nöthen M.M., Mcquillin A. Schizophrenia polygenic risk scores, clinical variables and genetic pathways as predictors of phenotypic traits of bipolar I disorder. Journal of Affective Disorders Jul 2024, 356, 507-518, doi:10.1016/j.jad.2024.04.066.

362. Gaman M.A., Srichawla B.S., Chen Y.F., Roy P., Dhali A., Nahian A., Manan M.R., Kipkorir V., Suteja R.C., Kutikuppala L.V.S., Gaman A.M., Diaconu C.C. Overview of dyslipidemia and metabolic syndrome in myeloproliferative neoplasms. World Journal Of Clinical Oncology Jun 24 2024, 15, doi:10.5306/wjco.v15.i6.717.

361. Alygizakis N., Ng K., Cirka L.U., Berendonk T., Cerqueira F., Cytryn E., Deviller G., Fortunato G., Iakovides I.C., Kampouris I., Michael-Kordatou I., Lai F.Y., Lundy L., Manaia C.M., Marano R.B.M., Paulus G.K., Piña B., Radu E., Rizzo L., Slipko K., Kreuzinger N., Thomaidis N.S., Ugolini V., Vaz-Moreira I., Slobodnik J., Fatta-Kassinos D. Making waves: The NORMAN antibiotic resistant bacteria and resistance genes database (NORMAN ARB & ARG) – an invitation for collaboration to tackle antibiotic resistance. Water Research Jun 2024, 257, doi:10.1016/j.watres.2024.121689.

360. Constantin M., Chifiriuc M.C., Bleotu C., Vrancianu C.O., Cristian R.E., Bertesteanu S.V., Grigore R., Bertesteanu G. Molecular pathways and targeted therapies in head and neck cancers pathogenesis. Frontiers in Oncology Jun 2024, 14, doi:10.3389/fonc.2024.1373821.

359. Gaman M.A., Mambet C., Neagu A.I., Bleotu C., Gurban P., Necula L., Botezatu A., Ataman M., Diaconu C.C., Ionescu B.O., Ghiaur A.E., Tatic A., Coriu D., Gaman A.M., Diaconu C.C. Assessment of total antioxidant capacity, 8-hydroxy-2′-deoxy-guanosine, the genetic landscape, and their associations in BCR::ABL-1-negative chronic and blast phase myeloproliferative neoplasms. International Journal of Molecular Sciences Jun 2024, 25, doi:10.3390/ijms25126652.

358. Gaman M.A., Scherber R.M., Ursuleac I., Crisan A.M., Badelita S.N., Ionescu B.O., Ghiaur A.E., Brinza M., Pirciulescu N., Lascar T.O., Diaconu C.C., Gaman A.M., Coriu D. Translation, cultural adaptation, and validation into Romanian of the myeloproliferative neoplasm symptom assessment form-total symptom score (MPN-SAF TSS or MPN-10) questionnaire. Journal of Clinical Medicine Jun 2024, 13, doi:10.3390/jcm13113284.

357. Klümper U., Gionchetta G., Catao E., Bellanger X., Dielacher I., Elena A.X., Fang P.J., Galazka S., Goryluk-Salmonowicz A., Kneis D., Okoroafor U., Radu E., Szadziul M., Szekeres E., Teban-Man A., Coman C., Kreuzinger N., Popowska M., Vierheilig J., Walsh F., Woegerbauer M., Bürgmann H., Merlin C., Berendonk T.U. Environmental microbiome diversity and stability is a barrier to antimicrobial resistance gene accumulation. Communications Biology Jun 2024, 7, doi:10.1038/s42003-024-06338-8.

356. Trandafir M.F., Savu O., Pasarica D., Bleotu C., Gheorghiu M. Interleukin-6 as a director of immunological events and tissue regenerative capacity in hemodialyzed diabetes patients. Medical Sciences Jun 2024, 12, doi:10.3390/medsci12020031.

355. Constantin M., Chifiriuc M.C., Mihaescu G., Corcionivoschi N., Burlibasa L., Bleotu C., Tudorache S., Mitache M.M., Filip R., Munteanu S.G., Pircalabioru G.G. Microbiome and cancer: From mechanistic implications in disease progression and treatment to development of novel antitumoral strategies. Frontiers in Immunology Apr 2024, 15, doi:10.3389/fimmu.2024.1373504

354. Mihaescu G., Chifiriuc M.C., Filip R., Bleotu C., Ditu L.M., Constantin M., Cristian R.E., Grigore R., Bertesteanu S.V., Bertesteanu G., Vrancianu C.O. Role of interferons in the antiviral battle: From virus-host crosstalk to prophylactic and therapeutic potential in SARS-CoV-2 infection. Frontiers in Immunology Jan 2024, 14, doi:10.3389/fimmu.2023.1273604.

353. Stoica S.I., Onose G., Bleotu C., Neagu A.I., Pitica I.M., Dragu D. Studies regarding influences of ethanol on hypoxemic stress in neuroblastoma cells. Balneo and Prm Research Journal Dec 2023, 14, doi:10.12680/balneo.2023.626.

352. Pirvu L.C., Pintilie L., Albulescu A., Stefaniu A., Neagu G. Anti-proliferative potential of cynaroside and orientin-in silico (DYRK2) and in vitro (U87 and Caco-2) studies. International Journal of Molecular Sciences. Dec 2023, 24, doi:10.3390/ijms242316555.

351. Manan M.R., Kipkorir V., Nawaz I., Waithaka M.W., Srichawla B.S., Gaman A.M., Diaconu C.C., Gaman M.A. Acute myocardial infarction in myeloproliferative neoplasms. World Journal of Cardiology Nov 2023, 15, 571-581, doi:10.4330/wjc.v15.i11.571.

350. Adesola A.A., Cozma M.A., Chen Y.F., Srichawla B.S., Gaman M.A. Risk of hepatitis B reactivation in patients with myeloproliferative neoplasms treated with ruxolitinib. WORLD JOURNAL OF HEPATOLOGY NOV 27 2023, 15, 1188-1195, doi:10.4254/wjh.v15.i11.1188.

349. Ionescu V.A., Gheorghe G., Bacalbasa N., Chiotoroiu A.L., Diaconu C. Colorectal cancer: From risk factors to oncogenesis. MEDICINA-LITHUANIA SEP 2023, 59, doi:10.3390/medicina59091646.

348. Diaconu C.C., Ellis R.J., Hermann D.M. Editorial: UN world AIDS day, a neuroscience perspective. Front Cell Neurosci 2023, 17, 1288615, doi:10.3389/fncel.2023.1288615.

347. Gurban P., Mambet C., Botezatu A., Necula L.G., Neagu A.I., Matei L., Pitica I.M., Nedeianu S., Chivu-Economescu M., Bleotu C., Ataman M., Mocanu G., Saguna C., Pavel A.G., Stambouli D., Sepulchre E., Anton G., Diaconu C.C., Constantinescu S.N. Leukemic conversion involving RAS mutations of type 1 CALR-mutated primary myelofibrosis in a patient treated for HCV cirrhosis: A case report. Front Oncol 2023, 13, 1266996, doi:10.3389/fonc.2023.1266996.

346. Chivu-Economescu M., Herlea V., Dima S., Sorop A., Pechianu C., Procop A., Kitahara S., Necula L., Matei L., Dragu D., Neagu A.I., Bleotu C., Diaconu C.C., Popescu I., Duda D.G. Soluble PD-L1 as a diagnostic and prognostic biomarker in resectable gastric cancer patients. Gastric Cancer 2023, 26, 934-946, doi:10.1007/s10120-023-01429-7.

345. Constantin M., Matanie C., Petrescu L., Bolocan A., Andronic O., Bleotu C., Mitache M.M., Tudorache S., Vrancianu C.O. Landscape of genetic mutations in appendiceal cancers. Cancers (Basel) 2023, 15, doi:10.3390/cancers15143591.

344. Vlad I.M., Nuta D.C., Ancuceanu R.V., Costea T., Coanda M., Popa M., Marutescu L.G., Zarafu I., Ionita P., Pirvu C.E.D., Bleotu C., Chifiriuc M.C., Limban C. Insights into the microbicidal, antibiofilm, antioxidant and toxicity profile of new o-aryl-carbamoyl-oxymino-fluorene derivatives. Int J Mol Sci 2023, 24, doi:10.3390/ijms24087020.

343.    Stoica S.I., Onose G., Pitica I.M., Neagu A.I., Ion G., Matei L., Dragu L.D., Radu L.-E., Chivu-Economescu M., Necula L.G. Molecular Aspects of Hypoxic Stress Effects in Chronic Ethanol Exposure of Neuronal Cells. Current Issues in Molecular Biology 2023, 45, 1655-1680.

342.    Botezatu A., Vladoiu S., Fudulu A., Albulescu A., Plesa A., Muresan A., Stancu C., Iancu I.V., Diaconu C.C., Velicu A., Popa O.M., Badiu C., Dinu-Draganescu D. Advanced molecular approaches in male infertility diagnosis(dagger). Biology of Reproduction 2022, 107, 684-704, doi:10.1093/biolre/ioac105.

341.    Necula L., Matei L., Dragu D., Pitica I., Neagu A., Bleotu C., Diaconu C.C., Chivu-Economescu M. Collagen Family as Promising Biomarkers and Therapeutic Targets in Cancer. International Journal of Molecular Sciences 2022, 23, doi:10.3390/ijms232012415.

340.    Iconaru S.L., Ciobanu C.S., Predoi G., Rokosz K., Chifiriuc M.C., Bleotu C., Stanciu G., Hristu R., Raaen S., Raita S.M., Ghegoiu L., Badea M.L., Predoi D. Biological and Physico-Chemical Properties of Composite Layers Based on Magnesium-Doped Hydroxyapatite in Chitosan Matrix. Micromachines 2022, 13, doi:10.3390/mi13101574.

339.    Grigoroiu-Serbanescu M., Bigdeli T., Herms S., Diaconu C.C., Neagu A.I., Van Der Veen T., Bass N., Nothen M.M., Forstner A.J., Mcquillin A. SCHIZOPHRENIA SNP-SET WAVE3 (2022) PREDICTS PSYCHOSIS, AGE OF ONSET AND AGE OF ONSET OF FIRST DEPRESSIVE EPISODE IN BIPOLAR I DISORDER. European Neuropsychopharmacology 2022, 63, E108-E108, doi:10.1016/j.euroneuro.2022.07.205.

338.    Radu E., Masseron A., Amman F., Schedl A., Agerer B., Endler L., Penz T., Bock C., Bergthaler A., Vierheilig J., Hufnagl P., Korschineck I., Krampe J., Kreuzinger N. Emergence of SARS-CoV-2 Alpha lineage and its correlation with quantitative wastewater-based epidemiology data. Water Research 2022, 215, doi:10.1016/j.watres.2022.118257.

337.    Petrisor G., Ficai D., Motelica L., Trusca R.D., Birca A.C., Vasile B.S., Voicu G., Oprea O.C., Semenescu A., Ficai A., Popitiu M.I., Fierascu I., Fierascu R.C., Radu E.L., Matei L., Dragu L.D., Pitica I.M., Economescu M., Bleotu C. Mesoporous Silica Materials Loaded with Gallic Acid with Antimicrobial Potential. Nanomaterials 2022, 12, doi:10.3390/nano12101648.

336.    Dumitrascu F., Udrea A.M., Caira M.R., Nuta D.C., Limban C., Chifiriuc M.C., Popa M., Bleotu C., Hanganu A., Dumitrescu D., Avram S. In Silico and Experimental Investigation of the Biological Potential of Some Recently Developed Carprofen Derivatives. Molecules 2022, 27, doi:10.3390/molecules27092722.

335.    Iconaru S.L., Predoi D., Ciobanu C.S., Motelica-Heino M., Guegan R., Bleotu C. Development of Silver Doped Hydroxyapatite Thin Films for Biomedical Applications. Coatings 2022, 12, doi:10.3390/coatings12030341.

334.    Constantinescu G., Gheorghe G., Ionescu V.A., Plotogea O.M., Sandru V., Diaconu C.C., Varlas V.N., Bacalbasa N., Diaconu C.C., Stan-Ilie M. COVID-19 Pandemic and Its Impact on Training Programs of Medical Residency in Romania. Gastroenterology Insights 2022, 13, 106-116, doi:10.3390/gastroent13010012.

333.    Chivu-Economescu M., Necula L.G., Matei L., Dragu D., Bleotu C., Sorop A., Herlea V., Dima S., Popescu I., Diaconu C.C. Collagen Family and Other Matrix Remodeling Proteins Identified by Bioinformatics Analysis as Hub Genes Involved in Gastric Cancer Progression and Prognosis. International Journal of Molecular Sciences 2022, 23, doi:10.3390/ijms23063214.

332.    Bala D., Jinga L.I., Popa M., Hanganu A., Voicescu M., Bleotu C., Tarko L., Nica S. Design, Synthesis, and Biological Evaluation of New Azulene-Containing Chalcones. Materials 2022, 15, doi:10.3390/ma15051629.

331.    Pasarica D., Gheorghiu M., Serban M., Toparceanu F., Ichim L., Badiu C. Response of inflammatory cytokines TNF, IL-6 and neurotrophin 3 (NT-3) in patients with secondary peritonitis. Febs Open Bio 2022, 12, 195-195.

330.    Chivu-Economescu M., Vremera T., Ruta S.M., Grancea C., Leustean M., Chiriac D., David A., Matei L., Diaconu C.C., Gatea A., Ilie C., Radu I., Cornienco A.M., Iancu L.S., Cirstoiu C., Pop C.S., Petru R., Strambu V., Malciolu S., Popescu C.P., Florescu S.A., Rafila A., Furtunescu F.L., Pistol A. Assessment of the Humoral Immune Response Following COVID-19 Vaccination in Healthcare Workers: A One Year Longitudinal Study. Biomedicines 2022, 10, doi:10.3390/biomedicines10071526.

329.    Botezatu A., Fudulu A., Iancu I.V., Bostan M., Mihaila M., Albulescu A., Diaconu C.C., Anton G., Plesa A. Assessment of HPV16 viral oncogenes’ role in genome-wide pattern deposition of MBD2/3 components of NuRD nucleosome remodeling complex. Febs Open Bio 2022, 12, 164-164.

328.    Zarafu I., Limban C., Radulescu C., Dulama I.D., Nuta D.C., Chirita C., Chifiriuc M.C., Badiceanu C.D., Popa M., Bleotu C., Dragu L.D., Stirbescu R.M., Bucurica I.A., Stanescu S.G., Ionita P. Novel Structures of Functionalized Graphene Oxide with Hydrazide: Characterization and Bioevaluation of Antimicrobial and Cytocompatibility Features. Coatings 2022, 12, doi:10.3390/coatings12010045.

327.    Vasilescu I.M., Chifiriuc M.C., Pircalabioru G.G., Filip R., Bolocan A., Lazar V., Ditu L.M., Bleotu C. Gut Dysbiosis and Clostridioides difficile Infection in Neonates and Adults. Frontiers in Microbiology 2022, 12, doi:10.3389/fmicb.2021.651081.

326.    Stoica S.I., Bleotu C., Ciobanu V., Ionescu A.M., Albadi I., Onose G., Munteanu C. Considerations about Hypoxic Changes in Neuraxis Tissue Injuries and Recovery. Biomedicines 2022, 10, doi:10.3390/biomedicines10020481.

325.    Chivu-Economescu M., Bleotu C., Grancea C., Chiriac D., Botezatu A., Iancu I.V., Pitica I., Necula L.G., Neagu A., Matei L., Dragu D., Sultana C., Radu E.L., Nastasie A., Voicu O., Ataman M., Nedeianu S., Mambet C., Diaconu C.C., Ruta S.M. Kinetics and persistence of cellular and humoral immune responses to SARS-CoV-2 vaccine in healthcare workers with or without prior COVID-19. Journal of Cellular and Molecular Medicine 2022, 26, 1293-1305, doi:10.1111/jcmm.17186.

324.    Amman F., Markt R., Endler L., Hupfauf S., Agerer B., Schedl A., Richter L., Zechmeister M., Bicher M., Heiler G., Triska P., Thornton M., Penz T., Senekowitsch M., Laine J., Keszei Z., Klimek P., Nagele F., Mayr M., Daleiden B., Steinlechner M., Niederstatter H., Heidinger P., Rauch W., Scheffknecht C., Vogl G., Weichlinger G., Wagner A.O., Slipko K., Masseron A., Radu E., Allerberger F., Popper N., Bock C., Schmid D., Oberacher H., Kreuzinger N., Insam H., Bergthaler A. Viral variant-resolved wastewater surveillance of SARS-CoV-2 at national scale. Nature Biotechnology 2022, 40, doi:10.1038/s41587-022-01387-y.

323.    Chifiriuc M.C., Filip R., Constantin M., Pircalabioru G.G., Bleotu C., Burlibasa L., Ionica E., Corcionivoschi N., Mihaescu G. Common themes in antimicrobial and anticancer drug resistance. Frontiers in Microbiology 2022, 13, doi:10.3389/fmicb.2022.960693.

322.    Levy G., Mambet C., Pecquet C., Bailly S., Havelange V., Diaconu C.C., Constantinescu S.N. Targets in MPNs and potential therapeutics. In Cellular and Molecular Aspects of Myeloproliferative Neoplasms, Bartalucci, N., Galluzzi, L., Eds.; International Review of Cell and Molecular Biology; 2022; Volume 366, pp. 41-81.

321.    Botezatu A., Plesa A., Iancu I.V., Bostan M., Mihaila M., Albulescu A., Fudulu A., Diaconu C.C., Anton G. E6 and E7 HPV16 oncogenes influence gene transcription trough the genome-wide pattern deposition of MBD2, 3 components of NuRD nucleosome remodeling complex. In Proceedings of the EUROPEAN JOURNAL OF HUMAN GENETICS, 2022; pp. 542-542.

320.    Wallmann L., Krampe J., Lahnsteiner J., Radu E., Van Rensburg P., Slipko K., Wogerbauer M., Kreuzinger N. Fate and persistence of antibiotic-resistant bacteria and genes through a multi-barrier treatment facility for direct potable reuse. Water Reuse 2021, 11, 373-390, doi:10.2166/wrd.2021.097.

319.    Chivu-Economescu M., Necula L., Matei L., Dragu D., Bleotu C., Diaconu C.C. Clinical Applications of Liquid Biopsy in Gastric Cancer. Frontiers in Medicine 2021, 8, doi:10.3389/fmed.2021.749250.

318.    Aspritoiu V.M., Stoica I., Bleotu C., Diaconu C.C. Epigenetic Regulation of Angiogenesis in Development and Tumors Progression: Potential Implications for Cancer Treatment. Frontiers in Cell and Developmental Biology 2021, 9, doi:10.3389/fcell.2021.689962.

317.    Visan A.I., Ristoscu C., Popescu-Pelin G., Sopronyi M., Matei C.E., Socol G., Chifiriuc M.C., Bleotu C., Grossin D., Brouillet F., Le Grill S., Bertrand G., Zgura I., Cristescu R., Mihailescu I.N. Composite Drug Delivery System Based on Amorphous Calcium Phosphate-Chitosan: An Efficient Antimicrobial Platform for Extended Release of Tetracycline. Pharmaceutics 2021, 13, doi:10.3390/pharmaceutics13101659.

316.    Badica P., Batalu N.D., Chifiriuc M.C., Burdusel M., Grigoroscuta M.A., Aldica G., Pasuk I., Kuncser A., Enculescu M., Popa M., Marutescu L.G., Gheorghe I., Thamer O., Bleotu C., Pircalabioru G.G., Operti L., Bonino V., Agostino A., Truccato M. MgB2 powders and bioevaluation of their interaction with planktonic microbes, biofilms, and tumor cells. Journal of Materials Research and Technology-Jmr&T 2021, 12, 2168-2184, doi:10.1016/j.jmrt.2021.04.003.

315.    Tihauan B.M., Marinas I.C., Bleotu C., Dolete G., Onisei T., Serbancea F., Mateescu C., Rascol M. Evaluation of cytotoxicity, nutritional and anti-oxidative status of lyophilized plant extracts used in dietary supplements. Romanian Biotechnological Letters 2021, 26, 2396-2405, doi:10.25083/rbl/26.2/2396.2405.

314.    Neacsu I.A., Leau S.A., Marin S., Holban A.M., Vasile B.S., Nicoara A.I., Ene V.L., Bleotu C., Kaya M.G.A., Ficai A. Collagen-Carboxymethylcellulose Biocomposite Wound-Dressings with Antimicrobial Activity. Materials 2021, 14, doi:10.3390/ma14051153.

313.    Bostan M., Mihaila M., Petrica-Matei G.G., Radu N., Hainarosie R., Stefanescu C.D., Roman V., Diaconu C.C. Resveratrol Modulation of Apoptosis and Cell Cycle Response to Cisplatin in Head and Neck Cancer Cell Lines. International Journal of Molecular Sciences 2021, 22, doi:10.3390/ijms22126322.

312.    Topoleanu S., Mambet C., Marutescu L., Ivan F., Cucu I.A., Curici A., Stoica I. Carrier frequencies for thrombophilia-related genetic variants in a Romanian cohort. Romanian Biotechnological Letters 2021, 26, 2275-2282, doi:10.25083/rbl/26.1/2275.2282.

311.    Stroe R., Mambet C., Curici A., Ivan F., Alexa L., Morjan C., Hodis N., Matei L., Dragu L.D., Lazar V., Bleotu C. Differential expression of NLRP3 inflammasome genes in HPV infected cervical cells. Romanian Biotechnological Letters 2021, 26, 2255-2261, doi:10.25083/rbl/26.1/2255.2261.

310.    Gheorghe I., Avram I., Corbu V.M., Marutescu L., Popa M., Balotescu I., Blajan I., Mateescu V., Zaharia D., Dumbrava A.S., Zetu O.E., Pecete I., Cristea V.C., Batalu D., Grigoroscuta M.A., Burdusel M., Aldica G.V., Badica P., Datcu A.D., Ianovici N., Bleotu C., Lazar V., Ditu L.M., Chifiriuc M.C. In Vitro Evaluation of MgB2 Powders as Novel Tools to Fight Fungal Biodeterioration of Heritage Buildings and Objects. Frontiers in Materials 2021, 7, doi:10.3389/fmats.2020.601059.

309.    Fudulu A., Olar R., Maxim C., Scaeteanu G.V., Bleotu C., Matei L., Chifiriuc M.C., Badea M. New Cobalt (II) Complexes with Imidazole Derivatives: Antimicrobial Efficiency against Planktonic and Adherent Microbes and In Vitro Cytotoxicity Features. Molecules 2021, 26, doi:10.3390/molecules26010055.

308.    Radu E., Woegerbauer M., Rab G., Oismuller M., Strauss P., Hufnagl P., Gottsberger R.A., Krampe J., Weyermair K., Kreuzinger N. Resilience of agricultural soils to antibiotic resistance genes introduced by agricultural management practices. Science of the Total Environment 2021, 756, doi:10.1016/j.scitotenv.2020.143699.

307.    Negrila C.C., Predoi D., Ghita R.V., Iconaru S.L., Ciobanu S.C., Manea M., Badea M.L., Costescu A., Trusca R., Predoi G., Stanciu G.A., Hristu R., Dragu L.D., Bleotu C., Groza A., Marinas I.C., Chifiriuc M.C. Multi-Level Evaluation of UV Action upon Vitamin D Enhanced, Silver Doped Hydroxyapatite Thin Films Deposited on Titanium Substrate. Coatings 2021, 11, doi:10.3390/coatings11020120.

306.    Popescu R., Gramescu M., Caba L., Panzaru M.C., Butnariu L., Braha E., Popa S., Rusu C., Cardos G., Zeleniuc M., Martiniuc V., Gug C., Paduraru L., Stamatin M., Diaconu C.C., Gorduza E.V. A Case of Inherited t(4;10)(q26;q26.2) Chromosomal Translocation Elucidated by Multiple Chromosomal and Molecular Analyses. Case Report and Review of the Literature. Genes 2021, 12, doi:10.3390/genes12121957.

305.    Hotoboc I.E., Fudulu A., Grigore R., Bertesteanu S., Huica I., Iancu I.V., Botezatu A., Bleotu C., Anton G. The association between lncRNA H19 and EZH2 expression in patients with EBV-positive laryngeal carcinoma. Acta Otorhinolaryngologica Italica 2021, 41, 537-543, doi:10.14639/0392-100x-n1527.

304.    Tiplea R.E., Lemnaru G.M., Trusca R.D., Holban A., Kaya M.G.A., Dragu L.D., Ficai D., Ficai A., Bleotu C. Antimicrobial Films based on Chitosan, Collagen, and ZnO for Skin Tissue Regeneration. Biointerface Research in Applied Chemistry 2021, 11, 11985-11995, doi:10.33263/briac114.1198511995.

303.    Badea M., Grecu M.N., Chifiriuc M.C., Bleotu C., Popa M., Iorgulescu E.E., Avram S., Uivarosi V., Munteanu A.C., Ghica D., Olar R. Insight on Ni(II) and Cu(II) complexes of biguanide derivatives developed as effective antimicrobial and antitumour agents. Applied Organometallic Chemistry 2021, 35, doi:10.1002/aoc.6155.

302.    Neacsu I.A., Matei L., Birca A.C., Nicoara A.I., Ene V.L., Dragu L.D., Ficai A., Bleotu C., Andronescu E. CURCUMIN – HYDROXYAPATITE SYSTEMS USED FOR BONE CANCER TREATMENT. Revista Romana De Materiale-Romanian Journal of Materials 2021, 51, 505-513.

301.    Cazacu I., Filippi A., Croitoru V., Kitahara S., Matsui A., Lauwers G., Sorop A., Necula L., Matei L., Pechianu C. 34P Validation of a new scoring system for molecular subtyping of gastric cancer. Annals of Oncology 2021, 32, S1356.

300.    Dragu D.L., Neagu A.I., Matei L., Bleotu C., Ruta S.M., Diaconu C.C. Characterization of a platform based on dendritic cells for new therapeutic vaccine development. Romanian Biotechnological Letters 2020, 25, 1899-1907, doi:10.25083/rbl/25.5/1899.1907.

299.    Nuta I., Badea M., Chifiriuc M.C., Bleotu C., Popa M., Daniliuc C.G., Olar R. Synthesis, physico-chemical characterization and bioevaluation of Ni(II), Pd(II), and Pt(II) complexes with 1-(o-tolyl)biguanide: Antimicrobial and antitumor studies. Applied Organometallic Chemistry 2020, 34, doi:10.1002/aoc.5807.

298.    Bostan M., Petrica-Matei G.G., Radu N., Hainarosie R., Stefanescu C.D., Diaconu C.C., Roman V. The Effect of Resveratrol or Curcumin on Head and Neck Cancer Cells Sensitivity to the Cytotoxic Effects of Cisplatin. Nutrients 2020, 12, doi:10.3390/nu12092596.

297.    Olar R., Badea M., Maxim C., Grumezescu A.M., Bleotu C., Marutescu L., Chifiriuc M.C. Anti-biofilm Fe3O4@C-18- 1,3,4 thiadiazolo 3,2-a pyrimidin-4-ium-2-thiolate Derivative Core-shell Nanocoatings. Materials 2020, 13, doi:10.3390/ma13204640.

296.    Vrancianu C.O., Popa L.I., Bleotu C., Chifiriuc M.C. Targeting Plasmids to Limit Acquisition and Transmission of Antimicrobial Resistance. Frontiers in Microbiology 2020, 11, doi:10.3389/fmicb.2020.00761.

295.    Temereanca A., Ene L., Rosca A., Diaconu C.C., Luca A., Burlacu R., Radoi R., Bulacu-Talnariu A., Marcotte T.D., Achim C.L., Ruta S. Neurocognitive Impairment in the Combined Antiretroviral Therapy Era in a Romanian Cohort of Young Adults with Chronic HIV Infection. Aids Research and Human Retroviruses 2020, 36, 367-372, doi:10.1089/aid.2019.0132.

294.    Neagu A.I., Mambet C., Necula L.G., Matei L., Dragu D.L., Ataman M., Petrica-Matei G.G., Alexiu I., Nedeianu S., Bleotu C., Stoian M., Diaconu C.C. Therapeutic potential of T regulatory cell manipulation: advantages and limitations. Romanian Biotechnological Letters 2020, 25, 1501-1510, doi:10.25083/rbl/25.2/1501.1510.

293.    Popescu-Pelin G., Ristoscu C., Duta L., Stan G.E., Pasuk I., Tite T., Stan M.S., Bleotu C., Popa M., Chifiriuc M.C., Oktar F.N., Nicarel A., Mihailescu I.N. Antimicrobial and Cytocompatible Bovine Hydroxyapatite-Alumina-Zeolite Composite Coatings Synthesized by Pulsed Laser Deposition from Low-Cost Sustainable Natural Resources. Acs Sustainable Chemistry & Engineering 2020, 8, 4026-4036, doi:10.1021/acssuschemeng.9b05031.

292.    Grigoroiu-Serbanescu M., Giaroli G., Thygesen J.H., Shenyan O., Bigdeli T.B., Bass N.J., Diaconu C.C., Neagu A.I., Forstner A.J., Degenhardt F., Herms S., Nothen M.M., Mcquillin A. Predictive power of the ADHD GWAS 2019 polygenic risk scores in independent samples of bipolar patients with childhood ADHD. Journal of Affective Disorders 2020, 265, 651-659, doi:10.1016/j.jad.2019.11.109.

291.    Necula L., Matei L., Dragu D., Pitica I., Neagu A.I., Bleotu C., Dima S., Popescu I., Diaconu C.C., Chivu-Economescu M. High plasma levels of COL10A1 are associated with advanced tumor stage in gastric cancer patients. World Journal of Gastroenterology 2020, 26, 3024-+, doi:10.3748/wjg.v26.i22.3024.

290.    Pitica I.M., Matei L., Dragu L.D., Alexandru G., Suciu A., Alexiu I.D., Neagu A.I., Chivu-Economescu M., Crisan I., Cristina M., Gabriela A., Diaconu C.C., Bleotu C. Tamarix gallica extract induces apoptosis via an intrinsic mechanism. Romanian Biotechnological Letters 2020, 25, 1701-1708, doi:10.25083/rbl/25.4/1701.1708.

289.    Zarafu I., Matei L., Bleotu C., Ionita P., Tatibouet A., Paun A., Nicolau I., Hanganu A., Limban C., Nuta D.C., Nemes R.M., Diaconu C.C., Radulescu C. Synthesis, Characterization, and Biologic Activity of New Acyl Hydrazides and 1,3,4-Oxadiazole Derivatives. Molecules 2020, 25, doi:10.3390/molecules25143308.

288.    Sorop A., Iacob R., Iacob S., Constantinescu D., Chitoiu L., Fertig T.E., Dinischiotu A., Chivu-Economescu M., Bacalbasa N., Savu L., Gheorghe L., Dima S., Popescu I. Plasma Small Extracellular Vesicles Derived miR-21-5p and miR-92a-3p as Potential Biomarkers for Hepatocellular Carcinoma Screening. Frontiers in Genetics 2020, 11, doi:10.3389/fgene.2020.00712.

287.    Zarafu I., Patrascu B., Marutescu L., Bleotu C., Limban C., Tatibouet A., Chifiriuc M.C., Nuta D.C., Ionita P. BIOEVALUATION OF THE ANTIMICROBIAL AND ANTI-PROLIFERATIVE POTENTIAL OF SOME DERIVATIVES OF 3,5-DINITRO-4-METHOXYAMINO-BENZOIC ACID. Farmacia 2020, 68, 8-14, doi:10.31925/farmacia.2020.1.2.

286.    Vlad I.M., Nuta D.C., Chirita C., Caproiu M.T., Draghici C., Dumitrascu F., Bleotu C., Avram S., Udrea A.M., Missir A.V., Marutescu L.G., Limban C. In Silico and In Vitro Experimental Studies of New Dibenz b,e oxepin-11(6H)one O-(arylcarbamoyl)-oximes Designed as Potential Antimicrobial Agents. Molecules 2020, 25, doi:10.3390/molecules25020321.

285.    Telehoiu A.T.B., Nuta D.C., Caproiu M.T., Dumitrascu F., Zarafu I., Ionita P., Badiceanu C.D., Avram S., Chifiriuc M.C., Bleotu C., Limban C. Design, Synthesis and In Vitro Characterization of Novel Antimicrobial Agents Based on 6-Chloro-9H-carbazol Derivatives and 1,3,4-Oxadiazole Scaffolds. Molecules 2020, 25, doi:10.3390/molecules25020266.

284.    Burlibasa L., Chifiriuc M.C., Lungu M.V., Lungulescu E.M., Mitrea S., Sbarcea G., Popa M., Marutescu L., Constantin N., Bleotu C., Hermenean A. Synthesis, physico-chemical characterization, antimicrobial activity and toxicological features of Ag-ZnO nanoparticles. Arabian Journal of Chemistry 2020, 13, 4180-4197, doi:10.1016/j.arabjc.2019.06.015.

283.    Burlacu R., Umlauf A., Marcotte T.D., Soontornniyomkij B., Diaconu C.C., Bulacu-Talnariu A., Temereanca A., Ruta S.M., Letendre S., Ene L., Achim C.L. Plasma CXCL10 correlates with HAND in HIV-infected women. Journal of Neurovirology 2020, 26, 23-31, doi:10.1007/s13365-019-00785-4.

282.    Panus E., Chifiriuc M.C., Bleotu C., Vrancianu C.O., Gradisteanu G., Rosoiu N. Impact of Different Parameters upon the Production of Virulence Factors in Escherichia coli Strains Isolated from Marine Water. Biointerface Research in Applied Chemistry 2020, 10, 7049-7060, doi:10.33263/briac106.70497060.

281.    Marcu A., Colita A., Radu L.E., Jercan C.G., Bica A.M., Asan M., Coriu D., Tanase A.D., Diaconu C.C., Mambet C., Botezatu A., Pasca S., Teodorescu P., Anton G., Gurban P., Colita A. Single-Center Experience With Epigenetic Treatment for Juvenile Myelomonocytic Leukemia. Frontiers in Oncology 2020, 10, doi:10.3389/fonc.2020.00484.

280.    Limban C., Chifiriuc M.C., Caproiu M.T., Dumitrascu F., Ferbinteanu M., Pintilie L., Stefaniu A., Vlad I.M., Bleotu C., Marutescu L.G., Nuta D.C. New Substituted Benzoylthiourea Derivatives: From Design to Antimicrobial Applications. Molecules 2020, 25, doi:10.3390/molecules25071478.

279.    Gradinaru L.M., Barbalata-Mandru M., Drobota M., Aflori M., Spiridon M., Pircalabioru G.G., Bleotu C., Butnaru M., Vlad S. Preparation and Evaluation of Nanofibrous Hydroxypropyl Cellulose and beta-Cyclodextrin Polyurethane Composite Mats. Nanomaterials 2020, 10, doi:10.3390/nano10040754.

278.    Chivu-Economescu M., Necula L.G., Matei L., Dragu D.L., Neagu A.I., Alexiu I., Bleotu C., Diaconu C.C. Gastrointestinal cancer stem cells as targets for innovative immunotherapy. World Journal of Gastroenterology 2020, 26, 1580-1593, doi:10.3748/wjg.v26.i14.1580.

277.    Rascu A.M., Otelea M.R., Mambet C., Handra C., Neagu A.I., Rascu A., Giurcaneanu C., Diaconu C.C. Modified Plasma Cytokine Profile in Occupational Dermatitis. Endocrine Metabolic & Immune Disorders-Drug Targets 2020, 20, 1295-1302, doi:10.2174/1871530320666200607194021.

276.    Bleotu C., Mambet C., Matei L., Dragu L.D. IMPROVING WINE QUALITY AND SAFETY THROUGH NANOTECHNOLOGY APPLICATIONS; 2020; Volume 20, pp. 437-458.

275.    Dragu D.L., Chivu-Economescu M., Bleotu C., Necula L.G., Matei L., Stoian M., Diaconu C.C. Establishing a mouse disease model for future studies regarding gastric anti-cancer therapies. Romanian Biotechnological Letters 2019, 24, 874-882, doi:10.25083/rbl/24.5/874.882.

274.    Patrinoiu G., Dumitru R., Culita D.C., Munteanu C., Birjega R., Calderon-Moreno J.M., Cucos A., Pelinescu D., Chifiriuc M.C., Bleotu C., Carp O. Self-assembled zinc oxide hierarchical structures with enhanced antibacterial properties from stacked chain-like zinc oxalate compounds. Journal of Colloid and Interface Science 2019, 552, 258-270, doi:10.1016/j.jcis.2019.05.051.

273.    Nitulescu G.M., Matei L., Aldea I.M., Draghici C., Olaru O.T., Bleotu C. Ultrasound-assisted synthesis and anticancer evaluation of new pyrazole derivatives as cell cycle inhibitors. Arabian Journal of Chemistry 2019, 12, 816-824, doi:10.1016/j.arabjc.2015.12.006.

272.    Mihai S., Codrici E., Popescu I.D., Enciu A.M., Rusu E., Zilisteanu D., Necula L.G., Anton G., Tanase C. Inflammation-Related Patterns in the Clinical Staging and Severity Assessment of Chronic Kidney Disease. Disease Markers 2019, 2019, doi:10.1155/2019/1814304.

271.    Tudose M., Culita D.C., Voicescu M., Musuc A.M., Kuncser A.C., Bleotu C., Popa M., Marutescu L., Chifiriuc M.C., Nicolescu M., Deleanu C. Fluorescent coumarin-modified mesoporous SBA-15 nanocomposite: Physico-chemical characterization and interaction with prokaryotic and eukaryotic cells. Microporous and Mesoporous Materials 2019, 288, doi:10.1016/j.micromeso.2019.109583.

270.    Ruta S., Burlacu R., Ene L., Umlauf A., Diaconu C., Rosca A., Temereanca A., Bulacu-Talnariu A., Soontornniyomkij B., Marcotte T., Achim C. Determinants of neurocognitive impairments in a Romanian cohort of young adults with chronic HIV infection. Hiv Medicine 2019, 20, 310-310.

269.    Bumbea H., Marcais A., Coriu D., Tanase A.D., Colita A., Bardas A., Lupu A.R., Vladareanu A.M., Onisai M.C., Popov V.M., Iordan I., Cisleanu M.D., Vasile D.S., Ciufu C.M., Varady Z., Craciun O.G., Georgescu D.G., Andreescu M., Mambet C., Diaconu C.C., Necula L., Bunaciu M., Necula A., Constantinescu S.N., Hermine O. Results from Treatment of a Large Cohort of ATL Patients from a Country with High HTLV1 Prevalence. Blood 2019, 134, doi:10.1182/blood-2019-126434.

268.    Tanase C., Popescu I.D., Enciu A.M., Gheorghisan-Galateanu A.A., Codrici E., Mihai S., Albulescu L., Necula L., Albulescu R. Angiogenesis in cutaneous T-cell lymphoma – proteomic approaches. Oncology Letters 2019, 17, 4060-4067, doi:10.3892/ol.2018.9734.

267.    Necula L., Matei L., Dragu D., Neagu A.I., Mambet C., Nedeianu S., Bleotu C., Diaconu C.C., Chivu-Economescu M. Recent advances in gastric cancer early diagnosis. World Journal of Gastroenterology 2019, 25, 2029-2044, doi:10.3748/wjg.v25.i17.2029.

266.    Neacsu I.A., Arsenie L.V., Trusca R., Ardelean I.L., Mihailescu N., Mihailescu I.N., Ristoscu C., Bleotu C., Ficai A., Andronescu E. Biomimetic Collagen/Zn2+-Substituted Calcium Phosphate Composite Coatings on Titanium Substrates as Prospective Bioactive Layer for Implants: A Comparative Study Spin Coating vs. MAPLE. Nanomaterials 2019, 9, doi:10.3390/nano9050692.

265.    Antohe M., Nedelcu R.I., Nichita L., Popp C.G., Cioplea M., Brinzea A., Hodorogea A., Calinescu A., Balaban M., Ion D.A., Diaconu C., Bleotu C., Pirici D., Zurac S.A., Turcu G. Tumor infiltrating lymphocytes: The regulator of melanoma evolution. Oncology Letters 2019, 17, 4155-4161, doi:10.3892/ol.2019.9940.

264.    Bleotu C., Socolov D., Stanculescu R., Socolov R., Anton M., Anton G. Methods of investigation of human microbiome in obstetrics and gynecology. Romanian Biotechnological Letters 2019, 24, 344-353, doi:10.25083/rbl/24.2/344.353.

263.    Tudos M., Anghel E.M., Culita D.C., Somacescu S., Calderon-Moreno J., Tecuceanu V., Dumitrascu F.D., Dracea O., Popa M., Marutescu L., Bleotu C., Curutiu C., Chifiriuc M.C. Covalent coupling of tuberculostatic agents and graphene oxide: A promising approach for enhancing and extending their antimicrobial applications. Applied Surface Science 2019, 471, 553-565, doi:10.1016/j.apsusc.2018.11.242.

262.    Zarafu I., Badea M., Ionita G., Chifiriuc M.C., Bleotu C., Popa M., Ionita P., Tatibouet A., Olar R. Thermal, spectral and biological characterisation of copper(II) complexes with isoniazid-based hydrazones. Journal of Thermal Analysis and Calorimetry 2019, 136, 1977-1987, doi:10.1007/s10973-018-7853-z.

261.    Ciocilteu M.V., Podgoreanu P., Delcaru C., Chifiriuc M.C., Manda C.V., Bita A., Popescu M., Amzoiu E., Croitoru O., Bleotu C., Bostan M., Neamtu J. PLGA-GENTAMICIN BIOCOMPOSITE MATERIALS WITH POTENTIAL ANTIMICROBIAL APPLICATIONS IN ORTHOPEDICS. Farmacia 2019, 67, 580-586, doi:10.31925/farmacia.2019.4.4.

260.    Vlaicu I.D., Olar R., Maxim C., Chifiriuc M.C., Bleotu C., Stanica N., Scaeteanu G.V., Dulea C., Avram S., Badea M. Evaluating the biological potential of some new cobalt (II) complexes with acrylate and benzimidazole derivatives. Applied Organometallic Chemistry 2019, 33, doi:10.1002/aoc.4976.

259.    Plaiasu V., Ozunu D., Motei G., Ivan M., Zeleniuc M., Cardos G., Gurban P., Dinulescu G., Diaconu C. Chromosomal microarray versus karyotyping for diagnosis of a rare inherited apparently balanced translocation involving chromosomes 13 & 21. European Journal of Human Genetics 2019, 27, 988-988.

258.    Gurban P., Mambet C., Botezatu A., Necula L.G., Matei L., Mocanu G., Saguna C., Nedeianu S., Chivu-Economescu M., Bleotu C., Lupu A., Anton G., Diaconu C.C., Constantinescu S.N. Type 1 calreticulin mutation in a chronic HCV-infected patient with progressive splenomegaly – NGS as a game changer. Febs Open Bio 2019, 9, 367-367.

257.    Albulescu A., Diaconu C.C., Fudulu A., Iancu I.V., Botezatu A., Plesa A., Huica I., Socolov D., Brasoveanu I., Anton G. hADA3 mutations in acquisition of hrHPV infection. Febs Open Bio 2019, 9, 159-160.

256.    Stroe R., Mambet C., Curici A., Ivan F., Alexa L., Morjan C., Lazar V., Bleotu C. The prevalence of hrHPV in a significant cohort of Romanian women. Romanian Biotechnological Letters 2019, 24, 75-81, doi:10.25083/rbl/24.1/75.81.

255.    Duta L., Chifiriuc M.C., Popescu-Pelin G., Bleotu C., Gradisteanu G., Anastasescu M., Achim A., Popescu A. Pulsed Laser Deposited Biocompatible Lithium-Doped Hydroxyapatite Coatings with Antimicrobial Activity. Coatings 2019, 9, doi:10.3390/coatings9010054.

254.    Nedelcu R.I., Balaban M., Turcu G., Brinzea A., Ion D.A., Antohe M., Hodorogea A., Calinescu A., Badarau A.I., Popp C.G., Cioplea M., Nichita L., Popescu S., Diaconu C., Bleotu C., Pirici D., Popescu R., Popescu C.M., Zurac S.A. Efficacy of methotrexate as anti-inflammatory and anti-proliferative drug in dermatology: Three case reports. Experimental and Therapeutic Medicine 2019, 18, 905-910, doi:10.3892/etm.2019.7511.

253.    Vasile O.R., Andronescu E., Trusca R., Vasile E., Holban A.M., Chifiriuc M.C., Iordache F., Maniu H., Bleotu C., Neacsu I.A., Vasile B.S. Structure-grain size-synthesis route of silver nanoparticles: a correlation with the cytotoxic effect. Romanian Journal of Morphology and Embryology 2019, 60, 617-628.

252.    Grigoroiu-Serbanescu M., Giaroli G., Thygesen J., Shenyan O., Bigdeli T., Bass N., Diaconu C.C., Forstner A.J., Nothen M.M., Mcquillin A. ADHD POLYGENIC RISK SCORES IN ROMANIAN AND UK BIPOLAR PATIENTS WITH CHILDHOOD ADHD. European Neuropsychopharmacology 2019, 29, 1206-1206, doi:10.1016/j.euroneuro.2018.08.255.

251.    Prodan A.M., Beuran M., Turculet C.S., Popa M., Andronescu E., Bleotu C., Raita S.M., Soare M., Lupescu O. In vitro evaluation of glycerol coated iron oxide nanoparticles in solution. Romanian Biotechnological Letters 2018, 23, 13901-13908, doi:10.26327/rbl2018.219.

250.    Zeleniuc M., Gurban P., Dinulescu G., Plaiasu V., Gorduza E.V., Diaconu C.C., Ozunu D.A., Motei G., Popa S., Cardos G. ArrayCGH study of Romanian patients with intellectual disability, developmental delay and malformations. European Journal of Human Genetics 2018, 26, 924-924.

249.    Plaiasu V.N., Ozunu D., Motei G., Zeleniuc M., Cardos G., Gurban P., Dinulescu G., Neagu A., Necula L., Mambet C., Pitica I.A., Matei L., Diaconu C. Rare genetic alterations involving chromosome 8: three pediatric cases. European Journal of Human Genetics 2018, 26, 978-978.

248.    Badea M., Calu L., Korosin N.C., David I.G., Chifiriuc M.C., Bleotu C., Ionita G., Silvestro L., Maurer M., Olar R. Thermal behaviour of some biological active perchlorate complexes with a triazolopyrimidine derivative. Journal of Thermal Analysis and Calorimetry 2018, 134, 665-677, doi:10.1007/s10973-018-7134-x.

247.    Murarasu D., Puiu L., Mihalcea C.E., Pitica I.M.A., Mambet C., Radu E.L., Matei L., Dragu D.L., Simion L., Marincas M.A., Chivu-Economescu M., Cinca S., Brasoveanu L., Bleotu C., Diaconu C.C. Characterization of TP53 polymorphisms in Romanian colorectal cancer patients. Romanian Biotechnological Letters 2018, 23, 14124-14134, doi:10.26327/rbl2017.04.

246.    Mambet C., Defour J.P., Babosova O., Leroy E., Necula L., Stanca O., Tatic A., Coriu D., Belickova M., Kralova B., Lanikova L., Saussoy P., Havelange V., Diaconu C.C., Divoky V., Constantinescu S.N. JAK2 R1063H Variant Enhances V617F Constitutive Signaling and Favors Development of Essential Thrombocythemia with Increased Hemoglobin and Neutrophils. Blood 2018, 132, doi:10.1182/blood-2018-99-117019.

245.    Duta L., Ristoscu C., Stan G.E., Husanu M.A., Besleaga C., Chifiriuc M.C., Lazar V., Bleotu C., Miculescu F., Mihailescu N., Axente E., Badiceanu M., Bociaga D., Mihailescu I.N. New bio-active, antimicrobial and adherent coatings of nanostructured carbon double-reinforced with silver and silicon by Matrix-Assisted Pulsed Laser Evaporation for medical applications. Applied Surface Science 2018, 441, 871-883, doi:10.1016/j.apsusc.2018.02.047.

244.    Chivu-Economescu M., Matei L., Necula L.G., Dragu D.L., Bleotu C., Diaconu C.C. New therapeutic options opened by the molecular classification of gastric cancer. World Journal of Gastroenterology 2018, 24, 1942-1961, doi:10.3748/wjg.v24.i18.1942.

243.    Murarasu D., Puiu L., Pitica I.M.A., Mambet C., Mihalcea C.E., Marincas A.M., Cinca S., Brasoveanu L., Diaconu C.C. TP53 somatic mutations and LOH profile in colorectal cancer in Romania. Romanian Biotechnological Letters 2018, 23, 13530-13540.

242.    Mambet C., Chivu-Economescu M., Matei L., Necula L.G., Dragu D.L., Bleotu C., Diaconu C.C. Murine models based on acute myeloid leukemia-initiating stem cells xenografting. World Journal of Stem Cells 2018, 10, 57-65, doi:10.4252/wjsc.v10.i6.57.

241.    Diaconu C.C., Mambet C., Necula L.G., Gurban P., Matei L., Aldea-Pitica I.M., Neagu A.I., Botezatu A., Bleotu C., Chivu-Economescu M., Roman V., Coriu D., Constantinescu S. Triple Negative Myeloproliferative Neoplasms – Sometimes Driver Mutations Stay Low-Key in Plain Sight. Romanian Biotechnological Letters 2018, 23, 13750-13760, doi:10.26327/rbl2017.12.

240.    Scaeteanu G.V., Chifiriuc M.C., Bleotu C., Kamerzan C., Marutescu L., Daniliuc C.G., Maxim C., Calu L., Olar R., Badea M. Synthesis, Structural Characterization, Antimicrobial Activity, and In Vitro Biocompatibility of New Unsaturated Carboxylate Complexes with 2,2-Bipyridine. Molecules 2018, 23, doi:10.3390/molecules23010157.

239.    Mitache M.M., Curutiu C., Gheorghe I., Lazar V., Bucur M., Bleotu C., Cochior D., Rusu E., Chifiriuc C.M. Phenotypic, Biochemical and Genotypic Charcaterisation of Some Factors Involved in the Virulence and Survival of Bacteria Isolated from Food and Food Processing Surfaces. Revista De Chimie 2018, 69, 116-120.

238.    Limban C., Missir A.V., Caproiu M.T., Grumezescu A.M., Chifiriuc M.C., Bleotu C., Marutescu L., Papacocea M.T., Nuta D.C. Novel Hybrid Formulations Based on Thiourea Derivatives and Core@Shell Fe3O4@C-18 Nanostructures for the Development of Antifungal Strategies. Nanomaterials 2018, 8, doi:10.3390/nano8010047.

237.    Zarafu I., Olar R., Chifiriuc M.C., Bleotu C., Ionita P., Multescu M., Ionita G., Gradisteanu G., Tatibouet A., Badea M. Synthesis, thermal, spectral, antimicrobial and cytotoxicity profile of the Schiff bases bearing pyrazolone moiety and their Cu(II) complexes. Journal of Thermal Analysis and Calorimetry 2018, 134, 1851-1861, doi:10.1007/s10973-018-7681-1.

236.    Mambet C., Babosova O., Defour J.P., Leroy E., Necula L., Stanca O., Tatic A., Berbec N., Coriu D., Belickova M., Kralova B., Lanikova L., Vesela J., Pecquet C., Saussoy P., Havelange V., Diaconu C.C., Divoky V., Constantinescu S.N. Cooccurring JAK2 V617F and R1063H mutations increase JAK2 signaling and neutrophilia in myeloproliferative neoplasms. Blood 2018, 132, 2695-2699, doi:10.1182/blood-2018-04-843060.

235.    Calu L., Badea M., Korosin N.C., Chifiriuc M.C., Bleotu C., Stanica N., Silvestro L., Maurer M., Olar R. Spectral, thermal and biological characterization of complexes with a Schiff base bearing triazole moiety as potential antimicrobial species. Journal of Thermal Analysis and Calorimetry 2018, 134, 1839-1850, doi:10.1007/s10973-018-7871-x.

234.    Mambet C., Necula L., Mihai S., Matei L., Bleotu C., Chivu-Economescu M., Stanca O., Tatic A., Berbec N., Tanase C., Diaconu C.C. Increased Dkk-1 plasma levels may discriminate disease subtypes in myeloproliferative neoplasms. Journal of Cellular and Molecular Medicine 2018, 22, 4005-4011, doi:10.1111/jcmm.13753.

233.    Burlacu R., Umlauf A., Marcotte T., Soontornniyomkij B., Diaconu C., Bulacu-Talnariu A., Temereanca A., Ruta S., Letendre S., Ene L., Achim C. Plasma IP-10: a potential biomarker of HAND in HIV plus women. Journal of Neurovirology 2018, 24, S10-S10.

232.    Burlacu R., Umlauf A., Marcotte T., Soontornniyomkij B., Diaconu C., Bulacu-Talnariu A., Temereanca A., Ruta S., Letendre S., Ene L., Achim C. Plasma IP-10: a potential biomarker of HAND in HIV plus women. Journal of Neuroimmune Pharmacology 2018, 13, S10-S10.

231.    Popa M., Marutescu L., Ion I., Kamerzan C., Bleotu C., Oprea E., Chifiriuc M.C., Lazar V. Antimicrobial and cytotoxic activity of graphene-based perioceuticals; 2018; pp. 585-599.

230.    Pop S., Enciu A.M., Necula L.G., Tanase C. Long non‐coding RNA s in brain tumours: Focus on recent epigenetic findings in glioma. Journal of cellular and molecular medicine 2018, 22, 4597-4610.

229.    Ngo A., Koay A., Pecquet C., Diaconu C.C., Jenkins D.A., Shiau A.K., Constantinescu S.N., Choong M.L. Phenotypic Screening for Inhibitors of a Mutant Thrombopoietin Receptor. In PHENOTYPIC SCREENING: Methods and Protocols, Wagner, B., Ed.; Methods in Molecular Biology; 2018; Volume 1787, pp. 53-66.

228.    Mihai S., Codrici E., Popescu I.D., Enciu A.M., Albulescu L., Necula L.G., Mambet C., Anton G., Tanase C. Inflammation-Related Mechanisms in Chronic Kidney Disease Prediction, Progression, and Outcome. Journal of Immunology Research 2018, 2018, doi:10.1155/2018/2180373.

227.    Gurgu H., Ștefănescu E., Nuță D.C., Teodor M., Căproiu F.D., Chifiriuc M.C., Bleotu C., Nițulescu G.M., Rădulescu F.Ş., Limban C. N-(1-ADAMANTYLCARBAMOTHIOYL) BENZAMIDES: SYNTHESIS, BIOLOGICAL EVALUATION AND ADME PREDICTIONS. Farmacia 2018, 66, 963-971.

226.    Calinescu A., Turcu G., Nedelcu R.I., Brinzea A., Hodorogea A., Antohe M., Diaconu C., Bleotu C., Pirici D., Jilaveanu L.B., Ion D.A., Badarau I.A. On the Dual Role of Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) in Human Malignancies. Journal of Immunology Research 2018, 2018, doi:10.1155/2018/7169081.

225.    Bleotu C., Matei L., Dragu L.D., Grigorescu L., Diaconu C.C., Anton G. Methods for Plant Genetic Modification; 2018; Volume 6, pp. 385-401.

224.    Ardelean I.L., Ficai D., Ficai A., Nechifor G., Dragu D., Bleotu C. SYNTHESIS AND CHARACTERIZATION OF NEW MAGNETITE NANOPARTICLES BY USING THE DIFFERENT AMINO ACIDS SUCH AS STABILIZING AGENTS. University Politehnica of Bucharest Scientific Bulletin Series B-Chemistry and Materials Science 2018, 80, 33-46.

223.    Telcian A., Hussien M.D., Chifiriuc M.C., Bleotu C., Holban A.M., Curutiu C., Grosu E., Ficai A., Mihaescu G., Grigore R., Ditu L.M. Assessment of the anti-biofilm activity and biocompatibility of novel PE and PVC polymers. Romanian Biotechnological Letters 2017, 22, 12997-13004.

222.    Plesa A., Botezatu A., Iancu I.V., Pitica I., Socolov D., Anton G. MOZ/MORF complex components expression levels in HPV-cervical cancer. Febs Journal 2017, 284, 225-225.

221.    Holban A.M., Grumezescu A.M., Ditu L.M., Curutiu C., Bleotu C., Grumezescu V., Chifiriuc C., Lazar V. Limonene functionalized magnetite nanoparticles for improved antimicrobial and immunomodulatory therapy. Febs Journal 2017, 284, 327-328.

220.    Tudose M., Culita D.C., Musuc A.M., Somacescu S., Ghica C., Chifiriuc M.C., Bleotu C. Lipoic acid functionalized SiO2@Ag nanoparticles. Synthesis, characterization and evaluation of biological activity. Materials Science and Engineering C-Materials for Biological Applications 2017, 79, 499-506, doi:10.1016/j.msec.2017.05.083.

219.    Hazem A., Pitica-Aldea I.M., Popescu C., Matei L., Dragu D., Economescu M., Alexiu I., Crisan I., Diaconu C.C., Bleotu C., Lupuliasa D. THE ANTIVIRAL/VIRUCIDAL EFFECTS OF ALCHOOLIC AND AQUEOUS EXTRACTS WITH PROPOLIS. Farmacia 2017, 65, 868-876.

218.    Chivu-Economescu M., Dragu D.L., Necula L.G., Matei L., Enciu A.M., Bleotu C., Diaconu C.C. Knockdown of KRT17 by siRNA induces antitumoral effects on gastric cancer cells. Gastric Cancer 2017, 20, 948-959, doi:10.1007/s10120-017-0712-y.

217.    Mitache M.M., Gheorghe I., Totea G., Bleotu C., Curutiu C., Cochior D., Rusu E., Chifiriuc M.C. Biochemical, Virulence and Resistance Features in Bacterial Strains Recovered from Hospital Surfaces after Decontamination with Quaternary Ammonium Compounds, Triclosan and Iodine Desinfectatnts. Revista De Chimie 2017, 68, 997-1001.

216.    Bleotu C., Chifiriuc M.C., Mircioaga D., Sandulescu O., Aldea I.M., Banu O., Ion D., Diaconu C.C., Marinescu F., Lazar V. The influence of nutrient culture media on Escherichia coli adhesion and biofilm formation ability. Romanian Biotechnological Letters 2017, 22, 12483-12491.

215.    Tanase C.P., Codrici E., Popescu I.D., Mihai S., Enciu A.M., Necula L.G., Preda A., Ismail G., Albulescu R. Prostate cancer proteomics: Current trends and future perspectives for biomarker discovery. Oncotarget 2017, 8, 18497-18512.

214.    Mihailescu I.N., Bociaga D., Popescu-Pelin G., Stan G.E., Duta L., Socol G., Chifiriuc M.C., Bleotu C., Lazar V., Husanu M.A., Zgura I., Miculescu F., Negut I., Hapenciuc C. Optimized silicon reinforcement of carbon coatings by pulsed laser technique for superior functional biomedical surfaces fabrication. Biofabrication 2017, 9, doi:10.1088/1758-5090/aa7076.

213.    Delcaru C., Podgoreanu P., Alexandru I., Popescu N., Marutescu L., Bleotu C., Mogosanu G.D., Chifiriuc M.C., Gluck M., Lazar V. Antibiotic Resistance and Virulence Phenotypes of Recent Bacterial Strains Isolated from Urinary Tract Infections in Elderly Patients with Prostatic Disease. Pathogens 2017, 6, doi:10.3390/pathogens6020022.

212.    Marutescu L., Calu L., Chifiriuc M.C., Bleotu C., Daniliuc C.G., Falcescu D., Kamerzan C.M., Badea M., Olar R. Synthesis, Physico-chemical Characterization, Crystal Structure and Influence on Microbial and Tumor Cells of Some Co(II) Complexes with 5,7-Dimethyl-1,2,4-triazolo 1,5-a pyrimidine. Molecules 2017, 22, doi:10.3390/molecules22071233.

211.    Saviuc C., Ciubuca B., Dinca G., Bleotu C., Drumea V., Chifiriuc M.C., Popa M., Pircalabioru G.G., Marutescu L., Lazar V. Development and Sequential Analysis of a New Multi-Agent, Anti-Acne Formulation Based on Plant-Derived Antimicrobial and Anti-Inflammatory Compounds. International Journal of Molecular Sciences 2017, 18, doi:10.3390/ijms18010175.

210.    Sandulescu O., Bleotu C., Matei L., Streinu-Cercel A., Oprea M., Dragulescu E.C., Chifiriuc M.C., Rafila A., Pirici D., Talapan D., Dorobat O.M., Negut A.C., Otelea D., Berciu I., Ion D.A., Codita I., Calistru P.I., Streinu-Cercel A. Comparative evaluation of aggressiveness traits in staphylococcal strains from severe infections versus nasopharyngeal carriage. Microbial Pathogenesis 2017, 102, 45-53, doi:10.1016/j.micpath.2016.11.006.

209.    Olar R., Vlaicu I.D., Chifiriuc M.C., Bleotu C., Stanica N., Scaeteanu G.V., Silvestro L., Dulea C., Badea M. Thermal behavior of new nickel(II) complexes with unsaturated carboxylates and heterocyclic N-donor ligands. Journal of Thermal Analysis and Calorimetry 2017, 127, 731-741, doi:10.1007/s10973-016-5445-3.

208.    Olar R., Calu L., Badea M., Chifiriuc M.C., Bleotu C., Velescu B., Stoica O., Ionita G., Stanica N., Silvestro L., Dulea C., Uivarosi V. Thermal behaviour of some biologically active species based on complexes with a triazolopyrimidine pharmacophore. Journal of Thermal Analysis and Calorimetry 2017, 127, 685-696, doi:10.1007/s10973-016-5425-7.

207.    Badea M., Bucur C., Chifiriuc M.C., Bleotu C., Grecu M.N., Lazar V., Marinescu D., Olar R. Insight on thermal behaviour of new complexes of Ni(II), Cu(II) and Zn(II) with a bismacrocyclic ligand developed as biologically active species. Journal of Thermal Analysis and Calorimetry 2017, 127, 487-497, doi:10.1007/s10973-016-5502-y.

206.    Zarafu I., Badea M., Ionita G., Ionita P., Paun A., Bucur M., Chifiriuc M.C., Bleotu C., Olar R. Spectral, magnetic, thermal and biological studies on Ca(II) and Cu(II) complexes with a novel crowned Schiff base. Journal of Thermal Analysis and Calorimetry 2017, 127, 1511-1521, doi:10.1007/s10973-016-5573-9.

205.    Turcu I., Zarafu I., Popa M., Chifiriuc M.C., Bleotu C., Culita D., Ghica C., Ionita P. Lipoic Acid Gold Nanoparticles Functionalized with Organic Compounds as Bioactive Materials. Nanomaterials 2017, 7, doi:10.3390/nano7020043.

204.    Sadik O., Ditu L.M., Gheorghe I., Pircalabioru G.G., Bleotu C., Banu O., Merezeanu N., Lupu A.C., Lazar V., Chifiriuc M.C. Adherence and Biofilm Formation in Candida albicans Strains Isolated from Different Infection Sites in Hospitalized Patients. Revista De Chimie 2017, 68, 2832-2835.

203.    Curutiu C., Ditu L.M., Iordache F., Bleotu C., Chifiriuc M.C., Lazar V., Paduraru D.N., Holban A.M. Quorum Sensing molecules produced by Pseudomonas aeruginosa impair attachment and biofilm formation in Candida albicans. Biointerface Research in Applied Chemistry 2017, 7, 2016-2020.

202.    Rada C., Andrei M., Tieranu C., Ispas A.T., Diaconu C.C., Baciu A. Ulcerative Colitis: Psychosocial Factors Involved. International Journal of Medical Research & Health Sciences 2017, 6, 27-35.

201.    Holban A.M., Bleotu C., Chifiriuc M.C., Lazar V. Phenotypic and Genetic Evaluation of the Influence of Pseudomonas aeruginosa Culture Fractions on the Human Mesenchymal Stem Cells Viability, Apoptotic Pathways and Cytokine Profile. Current Stem Cell Research & Therapy 2017, 12, 175-180, doi:10.2174/1574888×10666151026114817.

200.    Chivu-Economescu M., Rubach M. Hematopoietic Stem Cells Therapies. Current Stem Cell Research & Therapy 2017, 12, 124-133, doi:10.2174/1574888×10666151026114241.

199.    Chiru D., Mambet C., Matei L., Bleotu C., Ruta S., Diaconu C.C. Delivering the “Blueprints” or “DNA Repairing Kits” Instead of Drugs in the Treatment of Congenital Hemoglobinopathies. Current Organic Chemistry 2017, 21, 74-85, doi:10.2174/1385272820666160511122404.

197.    Bleotu C. Holistic Strategies for Drug Delivery (Part 2). Current Organic Chemistry 2017, 21, 3-3, doi:10.2174/138527282101161201202922.

198.    Butnariu L., Gramescu M., Caba L., Panzaru M., Braha E., Popescu R., Popa S., Rusu C., Cardos G., Zeleniuc M., Martiniuc V., Plaiasu V., Diaconu C., Gorduza E.V. USING OF MULTIPLE CHROMOSOMAL AND MOLECULAR ANALYSES TO ELUCIDATE THE ETIOLOGY OF PLURIMALFORMATIVE SYNDROMES. Medical-Surgical Journal-Revista Medico-Chirurgicala 2017, 121, 581-593.

196.    Tudose M., Culita D.C., Musuc A.M., Marinescu G., Somacescu S., Munteanu C., Bleotu C., Chifiriuc M.C. Multifunctional Silver Nanoparticles-Decorated Silica Functionalized with Retinoic Acid with Anti-Proliferative and Antimicrobial Properties. Journal of Inorganic and Organometallic Polymers and Materials 2016, 26, 1043-1052, doi:10.1007/s10904-016-0407-6.

195.    Negut A.C., Chifiriuc M.C., Sandulescu O., Streinu-Cercel A., Oprea M., Dragulescu E.C., Gheorghe I., Berciu I., Coralia B., Popa M., Otelea D., Talapan D., Dorobat O., Codita I., Popa M.I., Streinu-Cercel A. Bacteriophage-driven inhibition of biofilm formation in Staphylococcus strains from patients attending a Romanian reference center for infectious diseases. Fems Microbiology Letters 2016, 363, doi:10.1093/femsle/fnw193.

194.    Marinescu G., Culita D.C., Patron L., Stanica N., Nita S., Musuc A.M., Bleotu C., Popa M., Kamerzan C., Chifiriuc M.C. SYNTHESIS, CHARACTERIZATION AND EVALUATION OF THE ANTIMICROBIAL AND CYTOTOXIC ACTIVITY OF TWO NOVEL COMPLEXES OF Gd(III) WITH PIROXICAM AND MELOXICAM. Revue Roumaine De Chimie 2016, 61, 779-786.

193.    Gingasu D., Mindru I., Mocioiu O.C., Preda S., Stanica N., Patron L., Ianculescu A., Oprea O., Nita S., Paraschiv I., Popa M., Saviuc C., Bleotu C., Chifiriuc M.C. Synthesis of nanocrystalline cobalt ferrite through soft chemistry methods: A green chemistry approach using sesame seed extract. Materials Chemistry and Physics 2016, 182, 219-230, doi:10.1016/j.matchemphys.2016.07.026.

192.    Floroian L., Ristoscu C., Mihailescu N., Negut I., Badea M., Ursutiu D., Chifiriuc M.C., Urzica I., Dyia H.M., Bleotu C., Mihailescu I.N. Functionalized Antimicrobial Composite Thin Films Printing for Stainless Steel Implant Coatings. Molecules 2016, 21, doi:10.3390/molecules21060740.

191.    Botezatu A., Puiu M., Cucu N., Diaconu C.C., Badiu C., Arsene C., Iancu I.V., Plesa A., Anton G. Comparative molecular approaches in Prader-Willi syndrome diagnosis. Gene 2016, 575, 353-358, doi:10.1016/j.gene.2015.08.058.

190.    Mihailescu N., Stan G.E., Duta L., Chifiriuc M.C., Bleotu C., Sopronyi M., Luculescu C., Oktar F.N., Mihailescu I.N. Structural, compositional, mechanical characterization and biological assessment of bovine-derived hydroxyapatite coatings reinforced with MgF2 or MgO for implants functionalization. Materials Science & Engineering C-Materials for Biological Applications 2016, 59, 863-874, doi:10.1016/j.msec.2015.10.078.

189.    Mihailescu I.N., Bociaga D., Socol G., Stan G.E., Chifiriuc M.C., Bleotu C., Husanu M.A., Popescu-Pelin G., Duta L., Luculescu C.R., Negut I., Hapenciuc C., Besleaga C., Zgura I., Miculescu F. Fabrication of antimicrobial silver-doped carbon structures by combinatorial pulsed laser deposition. International Journal of Pharmaceutics 2016, 515, 592-606, doi:10.1016/j.ijpharm.2016.10.041.

188.    Gionea A., Andronescu E., Voicu G., Bleotu C., Surdu V.A. Influence of hot isostatic pressing on ZrO2-CaO dental ceramics properties. International Journal of Pharmaceutics 2016, 510, 439-448, doi:10.1016/j.ijpharm.2015.10.044.

187.    Balaure P.C., Popa R.A., Grumezescu A.M., Voicu G., Radulescu M., Mogoanta L., Balseanu T.A., Mogosanu G.D., Chifiriuc M.C., Bleotu C., Holban A.M., Bolocan A. Biocompatible hybrid silica nanobiocomposites for the efficient delivery of anti-staphylococcal drugs. International Journal of Pharmaceutics 2016, 510, 532-542, doi:10.1016/j.ijpharm.2016.03.037.

186.    Yipel M., Ghica M.V., Kaya M.G.A., Spoiala A., Radulescu M., Ficai D., Ficai A., Bleotu C., Cornelia N. Multifunctional Materials for Cancer Therapy: From Antitumoral Agents to Innovative Administration. Current Organic Chemistry 2016, 20, 2934-2948, doi:10.2174/1385272820666160919112919.

185.    Tanase C.P., Codrici E., Popescu I.D., Mihai S., Necula L., Albulescu R. Current Proteomic Studies for New Concept in Stem Cell Biology; 2016; pp. 235-280.

184.    Rusu E., Necula L.G., Neagu A.I., Alecu M., Stan C., Albulescu R., Tanase C.P. Current status of stem cell therapy: opportunities and limitations. Turkish Journal of Biology 2016, 40, 955-967, doi:10.3906/biy-1506-95.

183.    Ngo A., Koay A.Z., Pecquet C., Diaconu C.C., Ould-Amer Y., Huang Q.W., Kang C.B., Poulsen A., Lee M.A., Jenkins D., Shiau A., Constantinescu S.N., Choong M.L. A Phenotypic Screen for Small-Molecule Inhibitors of Constitutively Active Mutant Thrombopoietin Receptor Implicated in Myeloproliferative Neoplasms. Combinatorial Chemistry & High Throughput Screening 2016, 19, 824-833, doi:10.2174/1386207319666161010163825.

182.    Mambet C., Chivu-Economescu M., Matei L., Stoian M., Bleotu C. Strategies to Overcome Multi-Drug Resistance in Cancer Cells: the Contribution of siRNA and Nanotechnologies. Current Organic Chemistry 2016, 20, 2971-2982, doi:10.2174/1385272820666160510163625.

181.    Iconaru S.L., Turculet C., Le Coustumer P., Bleotu C., Chifiriuc M.C., Lazar V., Surugiu A., Badea M., Iordache F.M., Soare M., Prodan A.M. BIOLOGICAL STUDIES ON DEXTRIN COATED IRON OXIDE NANOPARTICLES. Romanian Reports in Physics 2016, 68, 1536-1544.

180.    Gionea A., Andronescu E., Bleotu C., Voicu G. THE INFLUENCE OF YTTRIA AND THERMAL HISTORY ON DENTAL ZIRCONIA CERAMICS. Revista Romana De Materiale-Romanian Journal of Materials 2016, 46, 17-24.

179.    Georgescu M., Gheorghe I., Curutiu C., Lazar V., Bleotu C., Chifiriuc M.C. Virulence and resistance features of Pseudomonas aeruginosa strains isolated from chronic leg ulcers. Bmc Infectious Diseases 2016, 16, doi:10.1186/s12879-016-1396-3.

178.    Delcaru C., Alexandru I., Podgoreanu P., Ditu L.-M., Cristea V.C., Bleotu C., Cotar A.I., Dragu D., Chifiriuc M.C., Lazar V. Modulation of quorum sensing genes expression in Pseudomonas aeruginosa clinical strains by supernatants of Bifidobacterium sp. probiotic strain. Biointerface Research in Applied Chemistry 2016, 6.

177.    Delcaru C., Alexandru I., Podgoreanu P., Cristea V.C., Bleotu C., Chifiriuc M.C., Bezirtzoglou E., Lazar V. Antagonistic activities of some Bifidobacterium sp. strains isolated from resident infant gastrointestinal microbiota on Gram-negative enteric pathogens. Anaerobe 2016, 39, 39-44.

176.    Bostan M., Mihaila M., Hotnog C., Bleotu C., Anton G., Roman V., Brasoveanu L.I. Modulation of Apoptosis in Colon Cancer Cells by Bioactive Compounds; 2016; pp. 51-87.

175.    Bleotu C. Holistic Strategies for Drug Delivery (Part 1). Current Organic Chemistry 2016, 20, 2933-2933, doi:10.2174/138527282028161104222629.

174.    Nitulescu G.M., Draghici C., Olaru O.T., Matei L., Ioana A., Dragu L.D., Bleotu C. Synthesis and apoptotic activity of new pyrazole derivatives in cancer cell lines. Bioorganic & Medicinal Chemistry 2015, 23, 5799-5808, doi:10.1016/j.bmc.2015.07.010.

173.    Ciulu-Costinescu F., Chifiriuc M.C., Popa M., Bleotu C., Neamtu J., Averis L.M.E., Bubulica M.V., Simionescu A., Aldea I.M., Belu I. Screening of Polyphenol Content and In vitro Studies of Antioxidant, Antibacterial and Cytotoxic Activities of Capsicum Annuum Extracts. Revista De Chimie 2015, 66, 1261-1266.

172.    Dragu D.L., Necula L.G., Bleotu C., Diaconu C.C., Chivu-Economescu M. Therapies targeting cancer stem cells: Current trends and future challenges. World Journal of Stem Cells 2015, 7, 1185-1201, doi:10.4252/wjsc.v7.i9.1185.

171.    Comanescu C., Bleotu C., Huica I., Radulescu M., Grancea C., Anton G. Non-invasive method for the evaluation of IL-6 and IL-10 levels in patients with chronic hepatitis C. Romanian Biotechnological Letters 2015, 20, 11018-11024.

170.    Dulamea A.O., Sirbu-Boeti M.P., Bleotu C., Dragu D., Moldovan L., Lupescu I., Comi G. Autologous mesenchymal stem cells applied on the pressure ulcers had produced a surprising outcome in a severe case of neuromyelitis optica. Neural Regeneration Research 2015, 10, 1841-1845, doi:10.4103/1673-5374.165325.

169.    Botezatu A., Iancu I.V., Plesa A., Diaconu C.C., Anton G., Florea R., Ilie V., Sorop A., Bacalbasa N., Tica V., Duda D.G., Dima S.O., Popescu I. Deregulation B-Catenin Gene Expression in Pancreatic Cancer. Pancreas 2015, 44, 1362-1363.

168.    Stoica P., Chifiriuc M.C., Rapa M., Bleotu C., Lungu L., Vlad G., Grigore R., Bertesteanu S., Stavropoulou E., Lazar V. Fabrication, characterization and bioevaluation of novel antimicrobial composites based on polycaprolactone, chitosan and essential oils. Romanian Biotechnological Letters 2015, 20, 10521-10535.

167.    Mambet C., Necula L.G., Neagu A.I., Aldea I.M., Matei L., Dragu D., Livadariu M., Economescu M., Bleotu C., Ion D., Diaconu C.C. HOX genes, reviewing the molecular bridges between developmental anomalies and cancer. Romanian Biotechnological Letters 2015, 20, 10504-10511.

166.    Ionescu D., Chifiriuc M.C., Ionescu B., Cristea V.C., Sacagiu B., Duta M., Neacsu G., Gilca R., Bleotu C., Bezirtzoglu E., Lazar V. Frequency and phenotypic virulence features of Streptococcus pyogenes strains isolated from throat carriage in Romanian population. Romanian Biotechnological Letters 2015, 20, 10470-10477.

165.    Ionescu B., Ionescu D., Gheorghe I., Curutiu C., Banu O., Bleotu C., Mihaescu G., Lazar V., Grigore R., Bezirtzoglou E., Bertesteanu S. Virulence patterns of Staphylococcus aureus hospital strains isolated in Bucharest, Romania. Romanian Biotechnological Letters 2015, 20, 10536-10546.

164.    Beuran M., Negoi I., Paun S., Ion A.D., Bleotu C., Negoi R.I., Hostiuc S. The epithelial to mesenchymal transition in pancreatic cancer: A systematic review. Pancreatology 2015, 15, 217-225, doi:10.1016/j.pan.2015.02.011.

163.    Ene L., Oliveira M.F., Tardei G., Diaconu C., Grancea C., Soontornniyomkij B., Ruta M.S., Smith D.M., Achim C.L. CMV impact on neurocognitive impairment in a cohort of Romanian young adults with chronic HIV-infection. Journal of Neurovirology 2015, 21, S19-S19.

162.    Olteanu A.A., Arama C.C., Bleotu C., Lupuleasa D., Monciu C.M. INVESTIGATION OF CYCLODEXTRIN BASED NANOSPONGES COMPLEXES WITH ANGIOTENSIN I CONVERTING ENZYME INHIBITORS (ENALAPRIL, CAPTOPRIL, CILAZAPRIL). Farmacia 2015, 63, 492-503.

161.    Antipa C., Popa M., Marutescu L., Bleotu C., Veronica L., Bertesteanu S., Grigore R., Bezirtzoglou E., Ruta S.M. Virulence Profiles of Bacterial Strains Isolated From Periodontal Lesions. Romanian Biotechnological Letters 2015, 20, 10662-10669.

160.    Torac E., Magda S.L., Vinereanu D., Gaman L., Stoian I., Torac A., Roceanu A., Bleotu C., Atanasiu V. CALCIPRESSIN PLASMA LEVEL DIFFERENCE BETWEEN ATHEROSCLEROTIC AND NON-ATHEROSCLEROTIC SUBJECTS. Atherosclerosis 2015, 241, E148-E148, doi:10.1016/j.atherosclerosis.2015.04.514.

159.    Banu O., Bleotu C., Burtea M., Cobzar I., Gheorghe I., Chifiriuc C. Prevalence of plasmid mediated beta-lactam genes amongst ESBL and CRE Klebsiella pneumoniae strains isolated from patients with cardiovascular disease. Febs Journal 2015, 282, 376-377.

158.    Botezatu A., Bleotu C., Nastase A., Anton G., Bacalbasa N., Duda D., Dima S.O., Popescu I. Epigenetic Silencing of GNMT Gene in Pancreatic Adenocarcinoma. Cancer Genomics & Proteomics 2015, 12, 21-30.

157.    Jankovic A., Erakovic S., Ristoscu C., Mihailescu N., Duta L., Visan A., Stan G.E., Popa A.C., Husanu M.A., Luculescu C.R., Srdic V.V., Janackovic D., Miskovic-Stankovic V., Bleotu C., Chifiriuc M.C., Mihailescu I.N. Structural and biological evaluation of lignin addition to simple and silver-doped hydroxyapatite thin films synthesized by matrix-assisted pulsed laser evaporation. Journal of Materials Science-Materials in Medicine 2015, 26, doi:10.1007/s10856-014-5333-y.

156.    Bleotu C., Chifiriuc M.C., Pircalabioru G., Bertesteanu S.G., Grigore R., Ruta S.M., Banu O., Lazar V. Significance of serum antibodies against HSP 60 and HSP 70 for the diagnostic of infectious diseases (vol 5, pg 828, 2014). Virulence 2015, 6, 101-101, doi:10.1080/21505594.2015.1012469.

155.    Matei L., Bleotu C., Baciu I., Diaconu C.C., Hanganu A., Banu O., Ionita P., Paun A., Tatibouet A., Zarafu I. Synthesis and biological activities of some new isonicotinic acid 2-(2-hydroxy-8-substituted-tricyclo 7.3.1.0(2.7) tridec-13-ylidene)-hydr azides. Bioorganic & Medicinal Chemistry 2015, 23, 401-410, doi:10.1016/j.bmc.2014.12.038.

154.    Grigoroiu-Serbanescu M., Diaconu C.C., Heilmann-Heimbach S., Neagu A.I., Becker T. Association of age-of-onset groups with GWAS significant schizophrenia and bipolar disorder loci in Romanian bipolar I patients. Psychiatry Research 2015, 230, 964-967, doi:10.1016/j.psychres.2015.11.008.

153.    Popa C.L., Bartha C.M., Albu M., Guegan R., Motelica-Heino M., Chifiriuc M.C., Bleotu C., Badea M.L., Antohe S. SYNTHESIS, CHARACTERIZATION AND CYTOTOXICITY EVALUATION ON ZINC DOPED HYDROXYAPATITE IN COLLAGEN MATRIX. Digest Journal of Nanomaterials and Biostructures 2015, 10, 681-691.

152.    Calu L., Badea M., Chifiriuc M.C., Bleotu C., David G.I., Ionita G., Marutescu L., Lazar V., Stanica N., Soponaru I., Marinescu D., Olar R. Synthesis, spectral, thermal, magnetic and biological characterization of Co(II), Ni(II), Cu(II) and Zn(II) complexes with a Schiff base bearing a 1,2,4-triazole pharmacophore. Journal of Thermal Analysis and Calorimetry 2015, 120, 375-386, doi:10.1007/s10973-014-3970-5.

151.    Tanase C., Albulescu R., Codrici E., Popescu I.D., Mihai S., Enciu A.M., Cruceru M.L., Popa A.C., Neagu A.I., Necula L.G., Mambet C., Neagu M. Circulating biomarker panels for targeted therapy in brain tumors. Future Oncology 2015, 11, 511-524, doi:10.2217/fon.14.238.

150.    Tanase C., Albulescu R., Codrici E., Calenic B., Popescu I.D., Mihai S., Necula L., Cruceru M.L., Hinescu M.E. Decreased expression of APAF-1 and increased expression of cathepsin B in invasive pituitary adenoma. Oncotargets and Therapy 2015, 8, 81-90, doi:10.2147/ott.s70886.

149.    Ionescu B., Ionescu D., Gheorghe I., Mihaescu G., Bleotu C., Sakizlian M., Banu O. Staphylococcus aureus virulence phenotypes among Romanian population. BIOINTERFACE RESEARCH IN APPLIED CHEMISTRY 2015, 5, 945-948.

148.    Ficai D., Sonmez M., Albu M.G., Mihaiescu D.E., Ficai A., Bleotu C. Antitumoral materials with regenerative function obtained using a layer-by-layer technique. Drug Design Development and Therapy 2015, 9, 1269-1279, doi:10.2147/dddt.s62805.

147.    Croitoru C.D., Mihaiescu D.E., Chifiriuc M.C., Bolocan A., Bleotu C., Grumezescu A.M., Saviuc C.M., Lazar V., Curutiu C. Efficiency of gentamicin loaded in bacterial polysaccharides microcapsules against intracellular Gram-positive and Gram-negative invasive pathogens. Romanian Journal of Morphology and Embryology 2015, 56, 1417-1421.

146.    Bolocan A., Mihaiescu D.E., Andronescu E., Voicu G., Grumezescu A.M., Ficai A., Vasile B.S., Bleotu C., Chifiriuc M.C., Pop C.S. Biocompatible hydrodispersible magnetite nanoparticles used as antibiotic drug carriers. Rom J Morphol Embryol 2015, 56, 365-370.

145.    Bleotu C., Chifiriuc M.C., Lazar V., Dragusel R., Matei L., Aldea I.M., Dragu L.D., Ionescu B., Diaconu C.C., Cernescu C., Mogoanta C.A., Popescu C.R., Popescu B., Grigore R., Bertesteanu S.V.G. Influence of Staphylococcus aureus attachment to the herpes simplex virus infected cells. Romanian Journal of Morphology and Embryology 2015, 56, 433-437.

144.    Mateescu A.L., Dimov T.V., Mitache M.M., Chifiriuc M.C., Bleotu C., Lazar V. Virulence and resistance markers in foodborne bacteria isolated in Bucharest, Romania. Febs Journal 2014, 281, 768-769.

143.    Ilie V.M., Tica V., Florea R., Sorop A., Ivan L., Uyy E., Suica V.I., Antohe F., Bacalbasa N., Eftimie M., Nastase A., Herlea V., Diaconu C., Bleotu C., Botezatu A., Paslaru L., Duda D., Popescu I., Dima S. The predictive role of S100A4 as a prometastatic factor in pancreatic ductal adenocarcinoma. Febs Journal 2014, 281, 692-693.

142.    Grumezescu V., Holban A.M., Grumezescu A.M., Socol G., Ficai A., Vasile B.S., Trusca R., Bleotu C., Lazar V., Chifiriuc C.M., Mogosanu G.D. Usnic acid-loaded biocompatible magnetic PLGA-PVA microsphere thin films fabricated by MAPLE with increased resistance to staphylococcal colonization. Biofabrication 2014, 6, doi:10.1088/1758-5082/6/3/035002.

141.    Ditu L.M., Chifiriuc M.C., Bezirtzoglou E., Marutescu L., Bleotu C., Pelinescu D., Mihaescu G., Lazar V. Immunomodulatory effect of non-viable components of probiotic culture stimulated with heat-inactivated Escherichia coli and Bacillus cereus on holoxenic mice. Microbial Ecology in Health and Disease 2014, 25, doi:10.3402/mehd.v25.23239.

140.    Daniela P., Toparceanu F., Gheorghiu M., Serban M., Ichim L., Bleotu C., Pasarica S.A., Bara C. Neurotrophin 3 (NT-3), interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF alpha) in various human pathologies. Febs Journal 2014, 281, 147-147.

139.    Botezatu A., Bleotu C., Nastase A., Anton G., Bacalbasa N., Duda D.G., Dima S.O., Popescu I. CpG islands promoter methylation the main cause for GNMT gene decreased expression in pancreatic adenocarcinoma. Febs Journal 2014, 281, 299-299.

138.    Bleotu C., Chifiriuc M.C., Pircalabioru G., Bertesteanu S.V.G., Grigore R., Ruta S.M., Lazar V. Significance of serum antibodies against HSP 60 and HSP 70 for the diagnostic of infectious diseases. Virulence 2014, 5, 828-831, doi:10.4161/21505594.2014.973800.

137.    Olar R., Patrascu F., Chifiriuc M.C., Iorgulescu E.E., Bleotu C., Marutescu L., Lazar V., Marinescu D., Stanica N., Badea M. Insight on thermal, spectral, magnetic and biological behaviour of new Ni(II), Cu(II) and Zn(II) complexes with a pentaazamacrocyclic ligand derived from nicotinamide. Journal of Thermal Analysis and Calorimetry 2014, 118, 1159-1168, doi:10.1007/s10973-014-3864-6.

136.    Dima S.O., Tica V., Eftimie M., Nastase A., Bacalbasa N., Herlea V., Diaconu C., Bleotu C., Chivu-Economescu M., Herlea V., Duda D., Popescu I. The Role of MAP4K4 and S100A4 in Pancreatic Ductal Adenocarcinoma. Pancreas 2014, 43, 1354-1354.

135.    Botezatu A., Bleotu C., Nastase A., Anton G., Bacalbasa N., Duda D., Dima S.O., Popescu I. Epigenetic Silencing of GNMT Gene in Pancreatic Adenocarcinoma. Pancreas 2014, 43, 1346-1346.

134.    Badea M., Vlaicu I.D., Olar R., Constand M., Bleotu C., Chifiriuc M.C., Marutescu L., Lazar V., Grecu M.N., Marinescu D. Thermal behaviour and characterisation of new biologically active Cu(II) complexes with benzimidazole as main ligand. Journal of Thermal Analysis and Calorimetry 2014, 118, 1119-1133, doi:10.1007/s10973-014-3745-z.

133.    Badea M., Patrascu F., Korosec R.C., Bukovec P., Raita M., Chifiriuc M.C., Marutescu L., Bleotu C., Velescu B., Marinescu D., Uivarosi V., Olar R. Thermal, spectral, magnetic and biologic characterization of new Ni(II), Cu(II) and Zn(II) complexes with a hexaazamacrocyclic ligand bearing ketopyridine moieties. Journal of Thermal Analysis and Calorimetry 2014, 118, 1183-1193, doi:10.1007/s10973-014-3857-5.

132.    Badea M., Calu L., Chifiriuc M.C., Bleotu C., Marin A., Ion S., Ionita G., Stanica N., Marutescu L., Lazar V., Marinescu D., Olar R. Thermal behaviour of some novel antimicrobials based on complexes with a Schiff base bearing 1,2,4-triazole pharmacophore. Journal of Thermal Analysis and Calorimetry 2014, 118, 1145-1157, doi:10.1007/s10973-014-3821-4.

131.    Grumezescu V., Socol G., Grumezescu A.M., Holban A.M., Ficai A., Trusca R., Bleotu C., Balaure P.C., Cristescu R., Chifiriuc M.C. Functionalized antibiofilm thin coatings based on PLA-PVA microspheres loaded with usnic acid natural compounds fabricated by MAPLE. Applied Surface Science 2014, 302, 262-267, doi:10.1016/j.apsusc.2013.09.081.

130.    Ionescu D., Aldea I.M., Bleotu C., Economescu M.C., Matei L., Rizea G.D., Crisan I., Diaconu C.C., Mihele D. EVALUATION OF ANTIVIRAL AND CYTOTOXIC ACTIVITIES OF TAMARIX GALLICA AND SILYBUM MARIANUM EXTRACTS. Farmacia 2014, 62, 329-340.

129.    Grumezescu A.M., Ghitulica C.D., Voicu G., Huang K.S., Yang C.H., Ficai A., Vasile B.S., Grumezescu V., Bleotu C., Chifiriuc M.C. New silica nanostructure for the improved delivery of topical antibiotics used in the treatment of staphylococcal cutaneous infections. International Journal of Pharmaceutics 2014, 463, 170-176, doi:10.1016/j.ijpharm.2013.07.016.

128.    Bucur C., Badea M., Chifiriuc M.C., Bleotu C., Iorgulescu E.E., Badea I.A., Grecu M.N., Lazar V., Patriciu O.I., Marinescu D., Olar R. Studies on thermal, spectral, magnetic and biological properties of new Ni(II), Cu(II) and Zn(II) complexes with a bismacrocyclic ligand bearing an aromatic linker. Journal of Thermal Analysis and Calorimetry 2014, 115, 2179-2189, doi:10.1007/s10973-013-3460-1.

127.    Popa C.L., Andronescu E., Stoicea M., Le Coustumer P., Galaup S., Beuran M., Iordache F.M., Telcian A., Bleotu C., Prodan A.M. FABRICATION, CHARACTERIZATION, TOXICITY AND BIOCOMPATIBILITY EVALUATION OF IRON OXIDE NANOPARTICLES. Digest Journal of Nanomaterials and Biostructures 2014, 9, 19-25.

126.    Holban A.M., Bleotu C., Chifiriuc M.C., Bezirtzoglou E., Lazar V. Role of Pseudomonas aeruginosa quorum sensing (QS) molecules on the viability and cytokine profile of human mesenchymal stem cells. Virulence 2014, 5, 303-310, doi:10.4161/viru.27571.

125.    Plesa A., Anton G., Iancu I.V., Diaconu C.C., Huica I., Stanescu A.D., Socolov D., Nistor E., Popa E., Stoian M., Botezatu A. Molecular variants of human papilloma virus 16 E2, E4, E5, E6 and E7 genes associated with cervical neoplasia in Romanian patients. Archives of Virology 2014, 159, 3305-3320, doi:10.1007/s00705-014-2199-8.

124.    Tanase C.P., Neagu A.I., Necula L.G., Mambet C., Enciu A.M., Calenic B., Cruceru M.L., Albulescu R. Cancer stem cells: Involvement in pancreatic cancer pathogenesis and perspectives on cancer therapeutics. World Journal of Gastroenterology 2014, 20, 10790-10801, doi:10.3748/wjg.v20.i31.10790.

123.    Jinga S.I., Voicu G., Stoica-Guzun A., Stroescu M., Grumezescu A.M., Bleotu C. BIOCELLULOSE NANOWHISKERS CEMENT COMPOSITES FOR ENDODONTIC USE. Digest Journal of Nanomaterials and Biostructures 2014, 9, 543-550.

122.    Grumezescu A.M., Gestal M.C., Holban A.M., Grumezescu V., Vasile B.S., Mogoanta L., Iordache F., Bleotu C., Mogosanu G.D. Biocompatible Fe3O4 Increases the Efficacy of Amoxicillin Delivery against Gram-Positive and Gram-Negative Bacteria. Molecules 2014, 19, 5013-5027, doi:10.3390/molecules19045013.

121.    Voicu G., Crica L.E., Fufa O., Moraru L.I., Popescu R.C., Purcel G., Stoilescu M.C., Grumezescu A.M., Bleotu C., Holban A.M., Andronescu E. Magnetite nanostructures functionalized with cytostatic drugs exhibit great anti-tumoral properties without application of high amplitude alternating magnetic fields. Romanian Journal of Morphology and Embryology 2014, 55, 357-362.

120.    Voicu G., Anghel A.G., Badea M., Bordei E., Crantea G., Gavrila R.I., Grecu A., Jercan D.a.M., Nicolae B.C., Vochitoaia G.C., Tchinda K., Holban A.M., Bleotu C., Grumezescu A.M. Silica network improve the effect of fludarabine and paclitaxel on HCT8 cell line. Romanian Journal of Morphology and Embryology 2014, 55, 545-551.

119.    Vlad M., Andronescu E., Grumezescu A.M., Ficai A., Voicu G., Bleotu C., Chifiriuc M.C. Carboxymethyl-cellulose/Fe3O4 nanostructures for antimicrobial substances delivery. Bio-Medical Materials and Engineering 2014, 24, 1639-1646, doi:10.3233/bme-140967.

118.    Sester M., Van Leth F., Bruchfeld J., Bumbacea D., Cirillo D.M., Dilektasli A.G., Dominguez J., Duarte R., Ernst M., Eyuboglu F.O. Risk assessment of tuberculosis in immunocompromised patients. A TBNET study. American journal of respiratory and critical care medicine 2014, 190, 1168-1176.

117.    Curutiu C., Chifiriuc M.C., Iordache F., Bleotu C., Lazar V., Mogoanta C.A., Popescu C.R., Grigore R., Bertesteanu S.V.G. Fluorescence analysis of apoptosis induced by Pseudomonas aeruginosa in endothelial cells. Romanian Journal of Morphology and Embryology 2014, 55, 313-317.

116.    Matei L., Bleotu C., Baciu I., Draghici C., Ionita P., Paun A., Chifiriuc M.C., Sbarcea A., Zarafu I. Synthesis and bioevaluation of some new isoniazid derivatives. Bioorganic & Medicinal Chemistry 2013, 21, 5355-5361, doi:10.1016/j.bmc.2013.06.013.

115.    Tanase C.P., Enciu A.M., Mihai S., Neagu A.I., Calenic B., Cruceru M.L. Anti-cancer Therapies in High Grade Gliomas. Current Proteomics 2013, 10, 246-260.

114.    Duda E., Codrici E., Popescu D.I., Necula L., Albulescu R. Protein Biomarkers in Cancers of the Digestive Tract – a Step Towards Personalized Medicine. Current Proteomics 2013, 10, 228-236.

113.    Holban A.M., Chifiriuc M.C., Cotar A.I., Bleotu C., Grumezescu A.M., Banu O., Lazar V. Virulence markers in Pseudomonas aeruginosa isolates from hospital-acquired infections occurred in patients with underlying cardiovascular disease. Romanian Biotechnological Letters 2013, 18, 8843-8854.

112.    Choong M.L., Pecquet C., Pendharkar V., Diaconu C.C., Yong J.W.Y., Tai S.J., Wang S.F., Defour J.P., Sangthongpitag K., Villeval J.L., Vainchenker W., Constantinescu S.N., Lee M.A. Combination treatment for myeloproliferative neoplasms using JAK and pan-class I PI3K inhibitors. Journal of Cellular and Molecular Medicine 2013, 17, 1397-1409, doi:10.1111/jcmm.12156.

111.    Grumezescu A.M., Andronescu E., Ficai A., Grumezescu V., Bleotu C., Saviuc C., Mihaiescu D.E., Chifiriuc C.M. Biocompatible Magnetic Hollow Silica Microspheres for Drug Delivery. Current Organic Chemistry 2013, 17, 1029-1033, doi:10.2174/1385272811317100005.

110.    Chifiriuc M.C., Grumezescu A.M., Saviuc C., Hristu R., Grumezescu V., Bleotu C., Stanciu G., Mihaiescu D.E., Andronescu E., Lazar V., Radulescu R. Magnetic Nanoparticles for Controlling in vitro Fungal Biofilms. Current Organic Chemistry 2013, 17, 1023-1028, doi:10.2174/1385272811317100004.

109.    Mihaiescu D.E., Cristescu R., Dorcioman G., Popescu C.E., Nita C., Socol G., Mihailescu I.N., Grumezescu A.M., Gudovan D., Enculescu M., Negrea R.F., Ghica C., Chifiriuc C., Bleotu C., Chrisey D.B. Functionalized magnetite silica thin films fabricated by MAPLE with antibiofilm properties. Biofabrication 2013, 5, doi:10.1088/1758-5082/5/1/015007.

108.    Badea M., Iosub E., Chifiriuc C.M., Marutescu L., Iorgulescu E.E., Lazar V., Marinescu D., Bleotu C., Olar R. Thermal, spectral, electrochemical and biologic characterization of new Pd(II) complexes with ligands bearing biguanide moieties. Journal of Thermal Analysis and Calorimetry 2013, 111, 1753-1761, doi:10.1007/s10973-012-2288-4.

107.    Matei L., Nitulescu G.M., Aldea I.M., Bleotu C., Chivu-Economescu M., Diaconu C.C. Synthesis and evaluation of antitumoral activity of some new pyrazolic compounds. Febs Journal 2013, 280, 306-307.

106.    Dragu D.L., Chivu-Economescu M., Necula L.G., Matei L., Diaconu C.C. New potentially targets to for inhibition the of metastatic and invasion capacity of gastric cancer cells. Febs Journal 2013, 280, 79-79.

105.    Mihaiescu D.E., Grumezescu A.M., Andronescu E., Voicu G., Ficai A., Vasile O.R., Bleotu C., Saviuc C. Prosthetic Devices with Functionalized Anti-biofilm Surface Based NanoAg@C18. Current Organic Chemistry 2013, 17, 105-112.

104.    Limban C., Grumezescu A.M., Chirea M., Matei L., Chifiriuc M.C. Antimicrobial Potential of Benzamides and Derived Nanosystems for Controlling in vitro Biofilm Development on Medical Devices. Current Organic Chemistry 2013, 17, 162-175, doi:10.2174/1385272811317020013.

103.    Grumezescu A.M., Andronescu E., Albu M.G., Ficai A., Bleotu C., Dragu D., Lazar V. Wound Dressing Based Collagen Biomaterials Containing Usnic Acid as Quorum Sensing Inhibitor Agent: Synthesis, Characterization and Bioevaluation. Current Organic Chemistry 2013, 17, 125-131.

102.    Bleotu C., Pircalabioru G., Dragusel R., Aldea I.M., Anca B., Banu O., Mihaescu G., Cernescu C.E., Diaconu C.C. Modulation of Interaction Between Virus and Eukaryotic Host by Exposure to S. aureus Bacterial Soluble Fractions. Current Organic Chemistry 2013, 17, 137-143, doi:10.2174/1385272811317020009.

101.    Bleotu C., Chifiriuc M.C., Grigore R., Grancea C., Popescu C.R., Anton G., Cernescu C. Investigation of Th1/Th2 cytokine profiles in patients with laryngo-pharyngeal, HPV-positive cancers. European Archives of Oto-Rhino-Laryngology 2013, 270, 711-718, doi:10.1007/s00405-012-2067-7.

100.    Voicu G., Geanaliu R.E., Ghitulica C.D., Ficai A., Grumezescu A.M., Bleotu C. Synthesis, characterization and bioevaluation of irinotecan-collagen hybrid materials for biomedical applications as drug delivery systems in tumoral treatments. Central European Journal of Chemistry 2013, 11, 2134-2143, doi:10.2478/s11532-013-0341-1.

99.      Grumezescu V., Chifiriuc C.M., Holban A.M., Stoica P., Grumezescu A.M., Voicu G., Socol G., Huang K.S., Bleotu C., Radulescu R. ANTIMICROBIAL AND BIOCOMPATIBILITY ASSAY OF NEWLY FABRICATED MATERIALS BASED COPPER OR ZINC ALGINATE AND SIO2 NETWORK. Digest Journal of Nanomaterials and Biostructures 2013, 8, 869-U507.

98.      Voicu G., Andronescu E., Grumezescu A.M., Huang K.S., Ficai A., Yang C.H., Bleotu C., Chifiriuc M.C. Antitumor Activity of Magnetite Nanoparticles: Influence of Hydrocarbonated Chain of Saturated Aliphatic Monocarboxylic Acids. Current Organic Chemistry 2013, 17, 831-840, doi:10.2174/1385272811317080008.

97.      Prodan A.M., Iconaru S.L., Chifiriuc C.M., Bleotu C., Ciobanu C.S., Motelica-Heino M., Sizaret S., Predoi D. Magnetic Properties and Biological Activity Evaluation of Iron Oxide Nanoparticles. Journal of Nanomaterials 2013, 2013, doi:10.1155/2013/893970.

96.      Albulescu R., Codrici E., Popescu I.D., Mihai S., Necula L.G., Petrescu D., Teodoru M., Tanase C.P. Cytokine Patterns in Brain Tumour Progression. Mediators of Inflammation 2013, 2013, doi:10.1155/2013/979748.

95.      Pasarica D., Gheorghiu M., Bleotu C., Toparceanu F., Mahler B., Serban M., Ichim L., Djeska C.S., Bara C. Interleukin 6 (IL-6) and neurotrophin 3 (NT-3) dynamics in patients with ischemic stroke (IS) and COPD. Febs Journal 2012, 279, 307-307.

94.      Cristescu R., Popescu C., Socol G., Iordache I., Mihailescu I.N., Mihaiescu D.E., Grumezescu A.M., Balan A., Stamatin I., Chifiriuc C., Bleotu C., Saviuc C., Popa M., Chrisey D.B. Magnetic core/shell nanoparticle thin films deposited by MAPLE: Investigation by chemical, morphological and in vitro biological assays. Applied Surface Science 2012, 258, 9250-9255, doi:10.1016/j.apsusc.2012.02.055.

93.      Anghel I., Limban C., Grumezescu A.M., Anghel A.G., Bleotu C., Chifiriuc M.C. In vitro evaluation of anti-pathogenic surface coating nanofluid, obtained by combining Fe3O4/C-12 nanostructures and 2-((4-ethylphenoxy)methyl)-N-(substituted-phenylcarbamothioyl)-benzamide s. Nanoscale Research Letters 2012, 7, doi:10.1186/1556-276x-7-513.

92.      Voicu G., Hadanoiu A.I., Andronescu E., Bleotu C. Binding Properties and Biocompatibility of Accelerated Portland Cement for Endodontic Use. Revista De Chimie 2012, 63, 1031-1034.

91.      Vassos E., Steinberg S., Cichon S., Breen G., Sigurdsson E., Andreassen O.A., Djurovic S., Morken G., Grigoroiu-Serbanescu M., Diaconu C.C., Czerski P.M., Hauser J., Babadjanova G., Abramova L.I., Muhleisen T.W., Nothen M.M., Rietschel M., Mcguffin P., St Clair D., Gustafsson O., Melle I., Pietilainen O.P.H., Ruggeri M., Tosato S., Werge T., Ophoff R.A., Rujescu D., Borglum A.D., Mors O., Mortensen P.B., Demontis D., Hollegaard M.V., Van Winkel R., Kenis G., De Hert M., Rethelyi J.M., Bitter I., Rubino I.A., Golimbet V., Kiemeney L.A., Van Den Berg L.H., Franke B., Jonsson E.G., Farmer A., Stefansson H., Stefansson K., Collier D.A., Grp C. Replication Study and Meta-Analysis in European Samples Supports Association of the 3p21.1 Locus with Bipolar Disorder. Biological Psychiatry 2012, 72, 645-650, doi:10.1016/j.biopsych.2012.02.040.

90.      Grumezescu A.M., Andronescu E., Ficai A., Bleotu C., Mihaiescu D.E., Chifiriuc M.C. Synthesis, characterization and in vitro assessment of the magnetic chitosan-carboxymethylcellulose biocomposite interactions with the prokaryotic and eukaryotic cells. International Journal of Pharmaceutics 2012, 436, 771-777, doi:10.1016/j.ijpharm.2012.07.063.

89.      Dima S.O., Tanase C., Albulescu R., Herlea V., Chivu-Economescu M., Purnichescu-Purtan R., Dumitrascu T., Duda D.G., Popescu I. An Exploratory Study of Inflammatory Cytokines as Prognostic Biomarkers in Patients With Ductal Pancreatic Adenocarcinoma. Pancreas 2012, 41, 1001-1007, doi:10.1097/MPA.0b013e3182546e13.

88.      Sonmez M., Ficai D., Stan A., Bleotu C., Matei L., Ficai A., Andronescu E. Synthesis and characterization of hybrid PVA/Al2O3 thin film. Materials Letters 2012, 74, 132-136, doi:10.1016/j.matlet.2012.01.062.

87.      Necula L.G., Chivu-Economescu M., Stanciulescu E.L., Bleotu C., Dima S.O., Alexiu I., Dumitru A., Constantinescu G., Popescu I., Diaconu C.C. IL-6 and IL-11 as Markers for Tumor Aggressiveness and Prognosis in Gastric Adenocarcinoma Patients without Mutations in Gp130 Subunits. Journal of Gastrointestinal and Liver Diseases 2012, 21, 23-29.

86.      Yamanaka S., Olaru A.V., An F.M., Luvsanjav D., Jin Z., Agarwal R., Tomuleasa C., Popescu I., Alexandrescu S., Dima S., Chivu-Economescu M., Montgomery E.A., Torbenson M., Meltzer S.J., Selaru F.M. MicroRNA-21 inhibits Serpini1, a gene with novel tumour suppressive effects in gastric cancer. Digestive and Liver Disease 2012, 44, 589-596, doi:10.1016/j.dld.2012.02.016.

85.      Constantinescu S., Pecquet C., Diaconu C., Staerk J., Girardot M., Royer Y., Defour J.P., Dusa A., Knoops L., Giraudier S., Villeval J.L., Courtoy P., Vainchenker W. MECHANISMS DRIVING THROMBOPOIETIN RECEPTOR DOWN MODULATION IN JAK2 V617F-POSITIVE MYELOPROLIFERATIVE NEOPLASMS. Haematologica 2012, 97, 372-372.

84.      Carmen D.C., Ana N.I., Razvan L., Gratiela T., Irina A., Mihaela C.E., Coralia B., Roxana B.S., Ioana A., Lilia M., Laura D.N., Irina P., Denisa D., Cosmin S.I., Alina N., Marius A., Bumbacea D. Regulatory T lymphocytes in evaluation of the local protective cellular immune response to Mycobacterium tuberculosis in Romanian patients. Romanian Biotechnological Letters 2012, 17, 6862-6868.

83.      Anghel I., Chifiriuc M.C., Mitache M., Marutescu L., Anghel A.G., Popa M., Pelinescu D., Bleotu C., Lazar V. PHENOTYPIC AND GENOTYPIC ASSESSMENT OF VIRULENCE FACTORS IN BETA-HEMOLYTIC STREPTOCOCCI ISOLATED FROM KINDERGARTEN INFANTILE POPULATION, WITH OR WITHOUT CLINICAL SYMPTOMS, INCLUDING SCARLET FEVER. Farmacia 2012, 60, 21-31.

82.      Remes C., Paun A., Zarafu I., Tudose M., Caproiu M.T., Ionita G., Bleotu C., Matei L., Ionita P. Chemical and biological evaluation of some new antipyrine derivatives with particular properties. Bioorganic Chemistry 2012, 41-42, 6-12, doi:10.1016/j.bioorg.2011.12.003.

81.      Pecquet C., Diaconu C.C., Staerk J., Girardot M., Marty C., Royer Y., Defour J.-P., Dusa A., Besancenot R., Giraudier S. Thrombopoietin receptor down-modulation by JAK2 V617F: restoration of receptor levels by inhibitors of pathologic JAK2 signaling and of proteasomes. Blood, The Journal of the American Society of Hematology 2012, 119, 4625-4635.

80.      Nitulescu G.M., Draghici C., Chifiriuc M.C., Marutescu L., Bleotu C., Missir A.V. Synthesis and antimicrobial screening of N-(1-methyl-1 H-pyrazole-4-carbonyl)-thiourea derivatives. Medicinal Chemistry Research 2012, 21, 308-314.

79.      Delcaru C., Chifiriuc M.C., Dracea O., Iordache C., Limban C., Nitulescu G.M., Missir A., Chirita I.C., Badiceanu C., Bleotu C. In vitro evaluation of the influence of compounds with tricyclic structure on the microbial growth and expression of virulence factors. African J Pharmacy and Pharmacology 2012, 6, 1631-1638.

78.      Choong M.L., Pecquet C., Tai S.J., Yong J.W., Pendharkar V., Wang S., Defour J.-P., Diaconu C.C., Sangthongpitag K., Villeval J.-L. Combination treatment with JAK2 and PI3K inhibitors in myeloproliferative neoplasms. Blood 2012, 120, 180.

77.      Bumbacea D., Lungu R., Pele I., Neagu A., Alexiu I., Economescu M.C., Bumbacea R.S., Diaconu C.C. New immunodiagnostic tests for latent and active tuberculosis. Revista Romana De Medicina De Laborator 2011, 19, 267-278.

76.      Dragu D.L., Economescu M.C., Necula L.G., Badea L., Dima S.O., Tudor S., Nastase A., Popescu I., Diaconu C.C. New molecular markers associated with gastric adenocarcinoma development and progression. Annals of Oncology 2011, 22, 26-26.

75.      Aldea I.M., Bleotu C., Brehar F., Botezatu A., Diaconu C., Chivu M., Lisievici M., Gorgan R.M., Anton G. Investigation of some epigenetic markers in glioblastoma. Annals of Oncology 2011, 22, 43-43.

74.      Cichon S., Muhleisen T.W., Degenhardt F.A., Mattheisen M., Miro X., Strohmaier J., Steffens M., Meesters C., Herms S., Weingarten M., Priebe L., Haenisch B., Aexander M., Vollmer J., Breuer R., Schmal C., Tessmann P., Moebus S., Wichmann H.E., Schreiber S., Muller-Myhsok B., Lucae S., Jamain S., Leboyer M., Bellivier F., Etain B., Henry C., Kahn J.P., Heath S., Hamshere M., O’donovan M.C., Owen M.J., Craddock N., Schwarz M., Vedder H., Kammerer-Ciernioch J., Reif A., Sasse J., Bauer M., Hautzinger M., Wright A., Mitchell P.B., Schofield P.R., Montgomery G.W., Medland S.E., Gordon S.D., Martin N.G., Gustafsson O., Andreassen O., Djurovic S., Sigurdsson E., Steinberg S., Stefansson H., Stefansson K., Kapur-Pojskic L., Oruc L., Rivas F., Mayoral F., Chuchalin A., Babadjanova G., Tiganov A.S., Pantelejeva G., Abramova L.I., Grigoroiu-Serbanescu M., Diaconu C.C., Czerski P.M., Hauser J., Zimmer A., Lathrop M., Schulze T.G., Wienker T.F., Schumacher J., Maier W., Propping P., Rietschel M., Nothen M.M., Bipolar Disorder Genome Study Bi G.S. Genome-wide Association Study Identifies Genetic Variation in Neurocan as a Susceptibility Factor for Bipolar Disorder. American Journal of Human Genetics 2011, 88, 372-381, doi:10.1016/j.ajhg.2011.01.017.

73.      Manolescu L., Temereanca A., Diaconu C.C., Ruta S. Correlation between resistance profile and immunosuppression in heavily treated HIV-1 infected Romanian patients. Romanian Biotechnological Letters 2011, 16, 6439-6449.

72.      Mihai M., Valentin N., Bogdan D., Carmen C.M., Coralia B., Demetra S. ANTIBIOTIC SUSCEPTIBILITY PROFILES OF MYCOPLASMA HOMINIS AND UREAPLASMA UREALYTICUM ISOLATED DURING A POPULATION-BASED STUDY CONCERNING WOMEN INFERTILITY IN NORTHEAST ROMANIA. Brazilian Journal of Microbiology 2011, 42, 256-260, doi:10.1590/s1517-83822011000100032.

71.      Chifiriuc C., Lazar V., Bleotu C., Calugarescu I., Grumezescu A.M., Mihaiescu D.E., Mogosanu D.E., Buteica A.S., Buteica E. BACTERIAL ADHERENCE TO THE CELLULAR AND INERT SUBSTRATE IN THE PRESENCE OF CoFe2O4 AND Fe3O4/OLEIC ACID – CORE/SHELL. Digest Journal of Nanomaterials and Biostructures 2011, 6, 37-42.

70.      Chifiriuc M.C., Pircalabioru G., Lazar V., Gilea B., Dascalu L., Enache G., Bleotu C. Immunogenicity of different cellular fractions of Vibrio parahaemolyticus strains grown under sub-lethal heat and osmotic stress. African Journal of Microbiology Research 2011, 5, 65-72.

69.      Anton G., Peltecu G., Socolov D., Cornitescu F., Bleotu C., Sgarbura Z., Teleman S., Iliescu D., Botezatu A., Goia C.D., Huica I., Anton A.C. Type-specific human papillomavirus detection in cervical smears in Romania. Apmis 2011, 119, 1-9, doi:10.1111/j.1600-0463.2010.02641.x.

68.      Zarnescu O., Brehar F.M., Bleotu C., Gorgan R.M. Co-localization of PCNA, VCAM-1 and caspase-3 with nestin in xenografts derived from human anaplastic astrocytoma and glioblastoma multiforme tumor spheres. Micron 2011, 42, 793-800, doi:10.1016/j.micron.2011.04.005.

67.      Ditu L.M., Chifiriuc M.C., Bezirtzoglou E., Voltsi C., Bleotu C., Pelinescu D., Mihaescu G., Lazar V. Modulation of virulence and antibiotic susceptibility of enteropathogenic Escherichia coli strains by Enterococcus faecium probiotic strain culture fractions. Anaerobe 2011, 17, 448-451, doi:10.1016/j.anaerobe.2011.05.019.

66.      Chifiriuc M.C., Banu O., Bleotu C., Lazar V. Interaction of bacteria isolated from clinical biofilms with cardiovascular prosthetic devices and eukaryotic cells. Anaerobe 2011, 17, 419-421, doi:10.1016/j.anaerobe.2011.04.016.

65.      Brehar F.M., Ciurea A.V., Zarnescu O., Bleotu C., Gorgan R.M., Dragu D., Matei L. Infiltrating growing pattern xenografts induced by glioblastoma and anaplastic astrocytoma derived tumor stem cells. Chirurgia 2010, 105, 685-694.

64.      Onose G., Brehar F.M., Ciurea A.V., Mohan D., Mitrica M., Bleotu C., Zarnescu O., Popescu C. NANO-TECHNOLOGICAL POSSIBLE DEVELOPMENT PATHWAYS WITHIN TARGETED-CELLS THERAPIES FOR INFILTRATIVE GLIOBLASTOMA CANCER STEM CELLS. In Proceedings of the International Conference TEX TEH 3 on Application of Nanotechnologies for Textiles, Bucharest, ROMANIA, Oct 07-08, 2010; pp. 152-161.

63.      Chivu-Economescu M., Necula L.G., Dragu D., Badea L., Dima S.O., Tudor S., Nastase A., Popescu I., Diaconu C.C. Identification of Potential Biomarkers for Early and Advanced Gastric Adenocarcinoma Detection. Hepato-Gastroenterology 2010, 57, 1453-1464.

62.      Grigoroiu-Serbanescu M., Herms S., Diaconu C.C., Jamra R.A., Meier S., Bleotu C., Neagu A.I., Prelipceanu D., Sima D., Gherghel M., Mihailescu R., Rietschel M., Nothen M.M., Cichon S., Muhleisen T.W. Possible association of different G72/G30 SNPs with mood episodes and persecutory delusions in bipolar I Romanian patients. Progress in Neuro-Psychopharmacology & Biological Psychiatry 2010, 34, 657-663, doi:10.1016/j.pnpbp.2010.03.008.

61.      Zarnescu O., Brehar F.M., Bleotu C., Gorgan R.M. Characterization of anaplastic astrocytoma xenografts derived from cancer stem cells in nude mice. Ejc Supplements 2010, 8, 148-148, doi:10.1016/s1359-6349(10)71382-3.

60.      Tanasescu C., Balanescu E., Balanescu P., Olteanu R., Badea C., Grancea C., Vagu C., Bleotu C., Ardeleanu C., Georgescu A. IL-17 in cutaneous lupus erythematosus. European Journal of Internal Medicine 2010, 21, 202-207, doi:10.1016/j.ejim.2010.03.004.

59.      Pasarica D., Toparceanu F., Gheorghiu M., Mahler B., Serban M., Berghea C., Ichim L., Bleotu C., Bara C. Neurotrophin 3 (NT-3) loses the immunomodulatory role in chronic diseases. Febs Journal 2010, 277, 180-180.

58.      Pasarica D., Gheorghiu M., Trandafir T., Ichim L., Toparceanu F., Bleotu C. Interleukin 6 (IL-6) and Neurotrophin 3 (NT-3) dynamics in children with meningitis and encephalitis. Febs Journal 2010, 277, 99-99.

57.      Panus E., Bleotu C., Rosoiu N., Popa M., Dascalu L., Ditu L.M., Lazar V., Chifiriuc M.C. Impact of different parameters upon the expression of certain virulence factors in escherichia coli strains isolated from marine water. Febs Journal 2010, 277, 103-104.

56.      Colita A., Colita A., Arion C., Lupu A., Puscariu T., Dobrea C., Closca M., Ciocan O., Diaconu C., Chivu M., Talmaci R., Coriu D., Avram S. FAVORABLE RESPONSE TO ALPHA-INTERFERON IN A PEDIATRIC PATIENT WITH AGNOGENIC MYELOID METAPLASIA COMBINED WITH FV LEIDEN ANOMALY. Haematologica-the Hematology Journal 2010, 95, 603-604.

55.      Alexiu I., Tardei G., Luca C., Chivu M., Sultana C., Grancea C., Stoian M., Diaconu C. Interleukin-6, tumor necrosis factor-alpha polymorphisms and HBV infection status in two transplant patient groups. Febs Journal 2010, 277, 52-52.

54.      Olar R., Badea M., Marinescu D., Chifiriuc M.C., Bleotu C., Grecu M.N., Iorgulescu E.E., Lazar V. N,N-dimethylbiguanide complexes displaying low cytotoxicity as potential large spectrum antimicrobial agents. European Journal of Medicinal Chemistry 2010, 45, 3027-3034, doi:10.1016/j.ejmech.2010.03.033.

53.      Olar R., Badea M., Marinescu D., Chifiriuc C.M., Bleotu C., Grecu M.N., Iorgulescu E.E., Bucur M., Lazar V., Finaru A. Prospects for new antimicrobials based on N,N-dimethylbiguanide complexes as effective agents on both planktonic and adhered microbial strains. European Journal of Medicinal Chemistry 2010, 45, 2868-2875, doi:10.1016/j.ejmech.2010.03.009.

52.      Bleotu C., Botezatu A., Goia C., Socolov D., Dragomir L., Popa E., Cornitescu F., Teleman S., Anton G. hTERT expression as a potential diagnostic marker. Romanian Biotechnological Letters 2010, 15, 4922-4930.

51.      Toparceanu F., Rusu R., Ichim L., Pasarica D., Chivu M. PROCALCITONIN (PCT), C-REACTIVE PROTEIN (CRP) AND CERULOPLASMIN (CP) AS SERUM MARKERS TO DISTINGUISH BETWEEN BACTERIAL AND VIRAL NEUROINFECTIONS. Child Care Health and Development 2010, 36, 80-80.

50.      Grigoroiu-Serbanescu M., Herms S., Diaconu C.C., Bleotu C., Neagu A.I., Abou Jamra R., Gherghel M., Sima D., Dan I.A., Prelipceanu D., Nothen M.M., Cichon S. G72/G30 CANDIDATE GENE FOR BIPOLAR I DISORDER IS NOT ASSOCIATED WITH PSYCHOSIS IN THE ROMANIAN POPULATION. European Psychiatry 2010, 25.

49.      Cheorghiu M., Pasarica D., Bleotu C., Toparrann F., Ichim L., Trandalir I. Rol of neurotrophin-3 on the innate immunity cytokines in patients with ischemic stroke. In Proceedings of the 2nd European Congress of Immunology (ECI), Berlin, GERMANY, Sep 13-16, 2009; pp. 545-+.

48.      Zarnescu O., Brehar F.M., Bleotu C., Lisievici M., Ciurea A.V. IMMUNOHISTOCHEMICAL COMPARISON BETWEEN HUMAN GLIOBLASTOMA AND THEIR XENOGRAFTS DERIVED FROM CANCER STEM CELLS IN NUDE MICE. Journal of Neurochemistry 2009, 110, 208-208.

47.      Chivu M., Dima S.O., Stancu C.I., Dobrea C., Uscatescu V., Necula L.G., Bleotu C., Tanase C., Albulescu R., Ardeleanu C., Popescu I. In vitro hepatic differentiation of human bone marrow mesenchymal stem cells under differential exposure to liver-specific factors. Translational Research 2009, 154, 122-132, doi:10.1016/j.trsl.2009.05.007.

46.      Grigoroiu-Serbanescu M., Herms S., Muhleisen T.W., Georgi A., Diaconu C.C., Strohmaier J., Czerski P., Hauser J., Leszczynska-Rodziewicz A., Jamra R.A., Babadjanova G., Tiganov A., Krasnov V., Kapiletti S., Neagu A.L., Vollmer J., Breuer R., Rietschel M., Propping P., Nothen M.M., Cichon S. Variation in P2RX7 Candidate Gene (rs2230912) Is Not Associated With Bipolar I Disorder and Unipolar Major Depression in Four European Samples. American Journal of Medical Genetics Part B-Neuropsychiatric Genetics 2009, 150B, 1017-1021, doi:10.1002/ajmg.b.30952.

45.      Brehar F.M., Bleotu C., Stefan L.M., Buzgariu W., Chivu M., Utoiu E., Matei L., Ciurea A.V., Tascu A. Isolation and partial characterization of a new human glioblastoma cell line. Chirurgia (Bucur) 2009, 104, 453-461.

44.      Morusciag L., Ditu L.M., Nitulescu G.M., Maracineanu S., Bleotu C., Mihaescu G. Antimicrobial activity screening of new 9-fluorenone derivatives towards some pathogen bacteria strains implicated in skin and mucosal lesions. Febs Journal 2009, 276, 329-329.

43.      Sirbu-Boeti M.P., Chivu M., Paslaru L.L., Efrimescu C., Herlea V., Pecheanu C., Moldovan L., Dragomir L., Bleotu C., Ciucur E., Vidulescu C., Vasilescu M., Boicea A., Manoiu S., Ionescu M.I., Popescu I. Transplantation of mesenchymal stem cells cultured on biomatrix support induces repairing of digestive tract iatrogenic defects. Chirurgia 2009, 104, 55-65.

42.      Lefter L.P., Dima S., Sunamura M., Furukawa T., Sato Y., Abe M., Chivu M., Popescu I., Horii A. Transcriptional silencing of ETS-1 efficiently suppresses angiogenesis of pancreatic cancer. Cancer Gene Therapy 2009, 16, 137-148, doi:10.1038/cgt.2008.65.

41.      Grigoroiu-Serbanescu M., Herms S., Georgi A., Hauser J., Czerski P., Diaconu C.C., Babadjanova G., Abou Jamra R., Rietschel M., Noethen M.M., Cichon S. BIPOLAR AND UNIPOLAR MAJOR DEPRESSION ARE NOT ASSOCIATED WITH THE P2RX7-GENE (SNP RS2230912) IN AN EUROPEAN CASE-CONTROL SAMPLE. European Psychiatry 2009, 24.

40.      Grigoroiu-Serbanescu M., Diaconu C.C., Herms S., Vollmer J., Bleotu C., Noethen M.M., Cichon S. TRYPTOPHAN HYDROXYLASE 2 (TPH2) GENE IN BIPOLAR I DISORDER IN THE ROMANIAN POPULATION. European Psychiatry 2009, 24.

39.      Grigoroiu-Serbanescu M., Diaconu C.C., Herms S., Bleotu C., Vollmer J., Muhleisen T.W., Prelipceanu D., Priebe L., Mihailescu R., Georgescu M.J., Sima D., Grimberg M., Nothen M.M., Cichon S. Investigation of the tryptophan hydroxylase 2 gene in bipolar I disorder in the Romanian population. Psychiatric Genetics 2008, 18, 240-247, doi:10.1097/YPG.0b013e3283053045.

38.      Panus E., Chifiriuc M.C.B., Bucur M., Cernat R., Mitache M., Nedelcu D., Bleotu C., Valeanu D., Lazar V., Rosoiu N. Virulence, pathogenicity, antibiotic resistance and plasmid profile of Escherichia coli strains isolated from drinking and recreational waters. Romanian Biotechnological Letters 2008, 13, 3695-3700.

37.      Chifiriuc M.C., Lixandru M., Iordache C., Bleotu C., Larion C., Olguta D., Lazar V., Antohe F., Israil A.M. Internalization of Staphylococcus aureus and Pseudomonas aeruginosa bacterial cells by non-phagocytic, epithelial human cells. Romanian Biotechnological Letters 2008, 13, 3651-3658.

36.      Chifiriuc M.C., Larion C., Iordache C., Lixandru M., Dracea O., Bleotu C., Bucur M., Israil A.M. Influence of soluble mediators upon the expression of different physiological and virulence hallmarks of bacteria. Romanian Biotechnological Letters 2008, 13, 3631-3642.

35.      Limban C., Chifiriuc M.C.B., Missir A.V., Chirita I.C., Bleotu C. Antimicrobial activity of some new thioureides derived from 2-(4-chlorophenoxymethyl) benzoic acid. Molecules 2008, 13, 567-580, doi:10.3390/molecules13030567.

34.      Plesa A., Goia C., Botezatu A., Bleotu C., Socolov D., Peltecu G., Cornitescu F., Anton G. Analysis of HPV DNA and P16 expression to predict prognosis in ASCUS, LSIL and HSIL in cervical swabs. Febs Journal 2008, 275, 274-274.

33.      Pasarica D., Gheorhiu M., Trandafi T., Bara C., Serban M., Toparceanu F., Ichim L., Bleotu C., Stoian M. Relation of neurotrophin 3 (NT-3) with interleukin 6 (IL-6) in serum and cerebrospinal fluid (CFS) from patients with viral neurological infections. Febs Journal 2008, 275, 317-317.

32.      Panus E., Rosoiu N., Balotescu C., Bleotu C., Mitache M. Effect of different physico-mechanical factors upon the growth and expression of virulence in Escherichia coli strains isolated from drinking and sea water. Febs Journal 2008, 275, 421-421.

31.      Goia C.D., Bleotu C., Antipa C., Lupu A.R., Closca M., Ciocan O., Anton G. Epstein-Barr virus latent gene expression and EBNA promoter methylation in non-Hodgkin lymphoma patients. Febs Journal 2008, 275, 103-103.

30.      Gheorghiu M., Pasarica D., Trandafir T., Diaconu C., Bleotu C., Prelipceanu D. Cytokines signals involved in alcoholic liver disease. Febs Journal 2008, 275, 306-306.

29.      Gheorghiu M., Pasarica D., Bara C., Trandafir T., Ichim L., Bleotu C., Alaicescu M., Popa C., Stoian M. Serum versus cerebrospinal dynamic of neurotrophin 3, tumoral necrosis factor alpha, interleukin 6 and interleukin 10 in patients with ischemic stroke. Febs Journal 2008, 275, 306-306.

28.      Bleotu C., Chivu M., Alexiu I., Anton G., Diakonu C.C., Neagu A., Cernescu C. New in vitro models for understanding molecular mechanism of oncogenesis. Febs Journal 2008, 275, 329-329.

27.      Anton M., Anton G., Sgarbura Z., Iliescu D., Bleotu C., Botezatu A., Goia C., Plesa A. E6 human papillomavirus type16 methylation in clinical specimens. Febs Journal 2008, 275, 102-102.

26.      Anton G., Bleotu C., Anton M., Socolov D., Teleman S., Goia C., Botezatu A. Altered cyclin expression in cervix preneoplasic lesions. Febs Journal 2008, 275, 267-267.

25.      Zarnescu O., Brehar F.M., Chivu M., Ciurea A.V. Immunohistochemical localization of caspase-3, caspase-9 and Bax in U87 glioblastoma xenografts. Journal of Molecular Histology 2008, 39, 561-569, doi:10.1007/s10735-008-9196-8.

24.      Anton G., Socolov D., Bleotu C., Anton A.C., Anton M., Goia C., Botezatu A. Viral markers as prognostic factors of cervical lesions progression. Ejc Supplements 2007, 5, 106-106, doi:10.1016/s1359-6349(07)70496-2.

23.      Staerk J., Kallin A., Royer Y., Diaconu C.C., Dusa A., Demoulin J.B., Vainchenker W., Constantinescu S.N. JAK2, the JAK2 V617F mutant and cytokine receptors. Pathologie Biologie 2007, 55, 88-91, doi:10.1016/j.patbio.2006.06.003.

22.      Chivu M., Nastasia S., Sultana C., Bleotu C., Alexiu I., Hudita D. Optimizing donor selection in order to establish a cord blood banking facility: maternal and obstetric factors impact. Central European Journal of Medicine 2007, 2, 180-189, doi:10.2478/s11536-007-0018-2.

21.      Pasarica D., Gheorghiu M., Bara C., Trandar T., Serban M., Toparceanu F., Bleotu C., Ichim L., Stoian M. Cytokine profile in acute neuroinflamation. Febs Journal 2007, 274, 190-190.

20.      Niculescu A., Ghetea L., Motoc R., Mihaescu G., Huculeci R., Diaconu C., Ursaciuc C., Savi G. P53 and rb (retinoblastoma) gene expression in tumoral cells, under the influence of a grape extract. Febs Journal 2007, 274, 155-155.

19.      Lazar V., Balotescu C., Bucur M., Banu O., Dobrin G., Bleotu C., Savu B., Sandulescu I., Stanciu I., Cernat R. P604 Investigation of the antimicrobial activity of different antibiotics on monospecific biofilms developed in vitro by microbial strains isolated from cardiovascular devices associated infections. International Journal of Antimicrobial Agents 2007, S141.

18.      Hinescu A.A., Cardos G., Diaconu C., Chivu M., Dragomir L., Closca M., Lupu A., Popescu D., Lungeanu A. Cytogenetic and molecular study of BCR/ABL negative chronic myeloproliferative disorders: preliminary data. In Proceedings of the CHROMOSOME RESEARCH, 2007; pp. 206-207.

17.      Balotescu C., Panus E., Bucur M., Cernat R., Nedelcu D., Bleotu C., Valeanu D., Lazar V. P1249 Virulence, pathogenicity, antibiotic resistance and plasmid profile of Escherichia coli strains isolated from drinking and recreational waters. International Journal of Antimicrobial Agents 2007, S343.

16.      Gheorghiu M., Slavoaca D., Pasarila D., Bara C., Tranadafir T., Ichim L., Bleotu C., Alaicescu M., Pop C., Stoian M. Neutrotrophin 3 and inflammatory cytokines dynamic in patients with ischemic stroke (IS) – Preliminary results. European Journal of Neurology 2006, 13, 52-52.

15.      Ionescu S., Diaconu C.C., Hillebrand M. Theoretical study of some verapamil derivatives. International Journal of Quantum Chemistry 2006, 106, 1457-1464, doi:10.1002/qua.20903.

14.      Pasarica D., Gheorghiu M., Bara C., Serban M., Trandafir T., Toparceanu F., Ichim L., Bleotu C., Popa C., Alaicescu M., Stoian M. Neurotrophin 3, tumoral necrosis factor alpha, interleukin 6 and acute phase proteins in patients with ischemic stroke. Febs Journal 2006, 273, 244-244.

13.      Anton G., Anton M., Plesa A., Bleotu C., Antipa E. P16 epigenetic alterations during cervical carcinogenesis. Febs Journal 2006, 273, 227-228.

12.      Bleotu C., Anton G., Plesa A., Chivu M., Alexiu I. Genomic plasticity is frequent in HPV-associated carcinogenesis. In Proceedings of the FEBS JOURNAL, 2006; pp. 355-355.

11.      Puiu L., Constantin M.C., Simioana M.D., Hotnog D., Diaconu C.C., Brasoveanu L.I. MODULATION OF DRUG-INDUCED APOPTOSIS IN BREAST CANCER CELL LINES. Anticancer Research 2004, 24, 3607-3608.

10.      Diaconu C.C., Bleotu C., Chivu M., Alexiu I., Petrusca D., Anton G., Achim R., Ruta S.M., Cernescu C. The development of larger cells that spontaneously escape senescence – a step during the immortalization of a human cancer cell line. Journal of Cellular and Molecular Medicine 2004, 8, 93-101, doi:10.1111/j.1582-4934.2004.tb00263.x.

9.         Paus S., Rietschel M., Schulze T.G., Ohlraun S., Diaconu C.C., Van Den Bogaert A., Maier W., Propping P., Cichon S., Nothen M.M. Systematic screening for mutations in the human N-methyl-D-aspartate receptor 1 gene in schizophrenic patients from the German population. Psychiatric Genetics 2004, 14, 233-234, doi:10.1097/00041444-200412000-00013.

8.         Chivu M., Diaconu C.C., Bleotu C., Alexiu I., Brasoveanu L., Cernescu C. The comparison of different protocols for expansion of umbilical-cord blood hematopoietic stem cells. Journal of Cellular and Molecular Medicine 2004, 8, 223-231, doi:10.1111/j.1582-4934.2004.tb00277.x.

7.         Plesa A., Anton G., Diaconu C., Stoian M., Repanovici R., Cernescu C. Cloning and expression of the L1 major capsid protein of the human papillomavirus 18 in murine cells. International Journal of Molecular Medicine 2003, 12, 1021-1026.

6.         Diaconu C.C., Szathmari M., Venetianer A. Antiproliferative and apoptosis-inducing effects of hemin in hepatoma cells. In Apoptosis: From Signaling Pathways to Therapeutic Tools, Diederich, M., Ed.; Annals of the New York Academy of Sciences; 2003; Volume 1010, pp. 311-315.

5.         Chivu M., Diaconu C.C., Brasoveanu L., Alexiu I., Bleotu C., Banceanu G., Miscalencu D., Cernescu C. Ex vivo differentiation of umbilical cord blood progenitor cells in the presence of placental conditioned medium. Journal of Cellular and Molecular Medicine 2002, 6, 609-619, doi:10.1111/j.1582-4934.2002.tb00459.x.

4.         Mutiu A., Alexiu I., Chivu M., Petica M., Anton G., Bleotu C., Diaconu C., Popescu C., Jucu V., Cernescu C. Detection of human papillomavirus gene sequences in cell lines derived from laryngeal tumors. Journal of Cellular and Molecular Medicine 2001, 5, 49-59, doi:10.1111/j.1582-4934.2001.tb00137.x.

3.         Tardei G., Duiculescu D., Capo C., Diaconu C.C., Mutiu A., Mege J.L., Cernescu C.E. Phagocytic function of monocytes in children with human immunodeficiency virus type 1 infection. Clinical and Diagnostic Laboratory Immunology 2000, 7, 296-297, doi:10.1128/cdli.7.2.296-297.2000.

2.         Diaconu C., Szathmari M., Keri G., Venetianer A. Apoptosis is induced in both drug-sensitive and multidrug-resistant hepatoma cells by somatostatin analogue TT-232. British journal of cancer 1999, 80, 1197-1203.

1.         Sahini V.E., Dumitrescu M., Volanschi E., Birla L., Diaconu C. Spectral and interferometrical study of the interaction of haemin with glutathione. Biophysical Chemistry 1996, 58, 245-253, doi:10.1016/0301-4622(95)00110-7.