THE RESEARCH AREA COVERED BY THE PhD PROGRAM
1. Viral infections with a major impact on public health (HIV infection, viral hepatitis, flu, CNS infections, emerging viruses).
2. Mechanisms involved in the pathogenesis of viral infections (viral infections in non-communicable diseases).
3. Molecular and cellular biology (including genetic and epigenetic factors) in human pathology.
4. Immunology, especially the subfield of tumor immunology.
5. Modulation of some biological processes.
6. Biotechnology/nanomedicine (in vitro studies on the biological effects induced by nanoparticles loaded with drugs/natural compounds).
7. Biology of tumor stem cells; the study of multiple drug resistance; in vitro studies on immunotherapeutic approaches in cancer.
8. Medical applications of new technologies (NGS-next generation sequencing, ChIP immunoprecipitation of chromatin, microarray).
9. Pharmacology, Pharmacokinetics.
10. Public health.
DOCTORAL RESEARCH DIRECTIONS IN STEFAN S. NICOLAU INSTITUTE OF VIROLOGY
VIROLOGY – PhD supervisor – Simona Ruţă, PhD
The content of the training program based on advanced university studies
Simona Ruţă is Professor of Virology and Vice-Rector for scientific research at the Carol Davila University of Medicine and Pharmacy in Bucharest, principal investigator, department for Emerging Viral Diseases, Ştefan S. Nicolau Institute of Virology and founding director of the International Center for research in the field of HIV/AIDS affiliated to the Baylor Pediatric AIDS Initiative, Texas, Houston, USA. She is corresponding member of the Academy of Medical Sciences and member of the Educational Subcomittee of the European Society for Clinical Microbiology and Infectious Diseases. Her main fields of research are the molecular epidemiology of HIV and viral hepatitis infections (antigenic heterogenicity of HIV strains circulating in Romania; emergence of HIV/HBV/HCV strains resistant to antiretrovirals), the impact of HIV on the central nervous system and the evolution of neurotropic emergent viral diseases. Author of over 100 articles indexed in international data bases, 54 in the Clarivate/ISI database with a cumulative factor >90 and more than 1000 citations. Project director or member in the research team of more than 30 national and international grants.
IMMUNOLOGY – PhD supervisor – Lorelei Brasoveanu, PhD
The content of the training program based on advanced university studies
Education: B.S from University of Polytechnics from Bucharest, Faculty of Chemistry, Biochemistry Department (now, Biochemistry Faculty from University of Bucharest) (in 1984); PhD fellow at Centro Regionale Oncologico di Aviano, Italy, in the Advanced Immunotherapy Department (1993-1996); PhD in Biology, Biochemistry specialization, since 1999. Present position – Head of the Center of Immunology from Stefan. S. Nicolau Institute for Virology (IVN) (since 2000), Senior Researcher (Ist degree, since 2006), PhD supervisor in Medicine (Immunology sub-domain, since 2006). Member of the Romanian Society of Immunology (affiliated to IUIS, EFIS, BAIS – since 1996), the Romanian Society of Biochemistry and Molecular Biology (affiliated to FEBS – since 2000), the Romanian Society for Cytometry (affiliated to ISAC – since 2008). Domains of interest: immunology, especially tumour immunology (biomarkers; tumour resistance; apoptosis; cancer stem cells), immunotherapeutical aproaches in cancer, molecular biology, nanomedicine (nanoparticles, organometallic and bioactive compounds), natural compounds. Technical skills and competences: cell cultures; cell-, complement- and drug-mediated cytotoxicity assays; ELISA; flow-cytometry techniques (apoptosis, cell cycle, antigen expression); Real-Time Cell Analysis (RTCA); RT-PCR approaches; SDS-PAGE/ Western blotting. Scientific activity: co-author of 1 book, 5 book chapters, 1 research patent, 57 published papers (30 ISI journals and 29 in peer-reviewed scientific journals); over 250 oral presentations and posters since 2005, presented in national (114) and international (142) conferences, and published as abstracts. Research activity focused on: tumor biomarkers (expression, functional roles); modulation of biomarker expression, biologic activities and signal transduction pathways by cytokines, natural compounds, anti-cancer drugs, nanoparticles; multi-drug resistance; imortalization of tumor cells from solid tumors; cancer stem-like cell cultures and characterization; complement regulators; apoptosis and cell-cycle key regulators. Management activities: Director/partner in national scientific projects; member of management council/team in European funded research projects (COST, POC, POS-CCE).The research abilities and good experience were acumulated in managing 3 international projects (1 as co-director, 2 as member of Management Council) and 16 national projects (11 as director, 5 as responsible partner); as a team member in 7 international projects and over 23 national research grants.
MOLECULAR BIOLOGY – PhD supervisor – Gabriela Anton, PhD
The content of the training program based on advanced university studies
Anton Gabriela, principal investigator, Molecular Virology Department, „Stefan S Nicolau” Institute of Virology, PhD supervisor in the field of medicine at the Romanian Academy. The research areas of interest cover genetic and epigenetic modifications in human pathologies and medical applications for „omic” technologies. Has authored over 200 scientific papers and communications (h index – 11), over 750 citations, out of which 500 in 2016 alone; project leader and team member in over 25 competition won projects; member of Romanian Biochemestry and Molecular Biology Society (FEBS affiliated), of Romanian Immunology Society (IUIS, EFIS and BAIS affiliated) and since 2005 member of European Association of Cancer Research (EACR); project evaluator for national and international competitions (EuroNanoMed).
TOXICOLOGY – PHARMACOLOGY – PhD supervisor – Acad. Victor Voicu, PhD
The content of the training programs based on advanced university studies
Academician Victor Voicu is the vicepresident of Romanian Academy Science since 2018, member of the Romanian Academy since 2001 (corresponding since 1991), president of Toxicology and Toxicodependence Commission in Ministry of Health (1998-2015), president of Scientific Council in Romanian National Medicine Agency (1997-2009). He is a university professor of Clinical Pharmacology, Toxicology and Psychopharmacology at the “Carol Davila” University of Medicine and Pharmacy in Bucharest and the President of the Romanian Society of Pharmacology, Therapeutics and Clinical Toxicology and also, member of the International Federation of Pharmaceutical Sciences, the European College of Neuropsychopharmacology, the American Chemical Society, the American College of Clinical Pharmacology. In 2005, he received the title of Doctor honoris causa from the “Ovidius” University in Constanta and the “Vasile Goldiş” University in Arad. On December 1, 2017 acad. Victor Voicu was decorated by the Presidency of Romania with the National Order “Steaua României” in the rank of Commander. Academician Victor Voicu is the author of over 20 monographic volumes, 300 published and communicated scientific works and holds almost 30 invention patents.
PUBLIC HEALTH – PhD supervisor – Daniela Mănuc, PhD
Discipline sheet 1 – Public health
Discipline sheet 2 – Preventive dentistry
Discipline sheet 3 – Management in the oral medicine office
Daniela Manuc, PhD Professor at the “Carol Davila” University of Medicine and Pharmacy, Bucharest, Faculty of Dental Medicine, Public Health Discipline. As responsibilities, Professor Manuc coordinates the activity of doctoral students and residents in the specialty Public Health and Management, coordination of undergraduate theses. Professor Manuc developed a series of works in the field of dental practice, as well as public health management and the ethics of medical professions in relation to patients. Between 2015 and 2017 she was Director – Senior Advisor in the Ministry of European Funds/ Ministry of Labor and Social Protection/ MDRAPFE – Management Authority for Sectoral Operational Program Human Resources Development/ General Directorate of Human Capital Programs. In 2016, was Head of Program Implementation and Coordination Unit – Ministry of Health. Between 2012 and 2016, was Deputy General Director of the Ministry of European Funds/Ministry of Labor and Social Protection – Management Authority for the Human Resources Development Sectoral Operational Program. Between 2001 and 2009 was Deputy General Director/ Head of the Program Implementation and Coordination Unit/ Director of Public Health – Ministry of Health.
VETERINARY MEDICINE- PhD supervisor – Nicolae Manolescu, PhD
Nicolae Manolescu is University professor Honoris Causa, Doctor Honoris Causa, professor Emeritus, correspondent member of the Romanian Academy, a corresponding member of the French Academy of Medicine. Doctoral supervisor at the School of Advanced Studies of the Romanian Academy, Veterinary Medicine Field; Scientific director – Spiru Haret University, Bucharest; Professor Pathological Anatomy Department, Spiru Haret University, Faculty of Veterinary Medicine; Founding president of the Association One Health-New Medical Concept, Romania. President of Section at the Academy of Medical Sciences – Comparative Medicine Section Fields of competence: pathological anatomy, comparative oncology, cell pathology, biotechnology.
PhD ADMISSIONS
Required documents for the registration to the doctoral colloquium:
- registration application (Standard document 2)
- birth certificate (legalized copy);
- marriage certificate or other name change document (legalized copy);
- identity card (xerox copy);
- baccalaureate diploma (certified copy);
- bachelor’s degree and transcript (certified copies);
- master’s degree and transcript (certified copies);
- certificate of passing a language proficiency exam (minimum level B2, according to the reference framework of the Council of Europe);
- other certificates attesting university and/or postgraduate training in the field (legalized copies);
- curriculum vitae – European model (Part I – CV, Part II – descriptionscientific activity);
- the list of scientific works published in the chosen field of study;
- the bibliographic list with the specialized literature studied for the admission interview;
- personal details file (Standard document 3)
- proposal regarding the doctoral thesis to be developed and a brief presentation of to it – 1.2 pages (Standard document 1)
- employee certificate if the candidate is employed;
- for foreign citizens – the certificate of linguistic competence regarding the knowledge of the Romanian language/or to submit certificates/diplomas proving at least 4 consecutive years of studies in Romania.
STRUCTURE OF THE DOCTORAL TRAINING PROGRAM
Doctoral university studies are planned for a period of 4 academic years and include:
- A training program based on advanced university studies, completed within a doctoral school and made up of activities carried out in institutionalized study formations;
- An individual program of scientific research/artistic creation.
The first year of doctoral studies includes the training program based on advanced university studies, which includes mandatory subjects: Scientific research methodology; Ethic and academic integrity; Structural and functional genomics.
The field of research covered by the doctoral program also includes the disciplines: Virology; Public healt; Molecular biology; Immunology; Toxicology
At least 4 disciplines are mandatory.
The first year ends with the presentation of a Research Project in front of a committee.
The second year consists of setting up the research plan, establishing the objectives, perfecting the methodology, recruiting the study group and presenting a scientific report on a theme derived from the paper.
The third year consists of the analysis of the study material, the development of the statistical apparatus, the follow-up of the specialized literature on the established topic and the presentation of a scientific report on a topic derived from the paper.
Year IV is the year of writing, finalizing and presenting the thesis.
During years II, III, IV, the doctoral student will present information regarding the progress stage of the thesis.
Doctoral studies end with the public submission of an original work (doctoral thesis), which is the result of the research or artistic creation carried out by the doctoral student during the doctoral university studies. Based on the doctorate thesis and its public support, it is decided whether or not to award the doctorate.
CURRENT AND PREVIOUSLY PhD ACTIVITY
SCOSAAR METHODOLOGIES
• METHODOLOGY OF THE ADMISSION COMPETITION ORGANIZATION AND CONDUCT TO UNIVERSITY DOCTORAL STUDIES (English)
• METHODOLOGY OF THE ADMISSION COMPETITION ORGANIZATION AND CONDUCT TO UNIVERSITY DOCTORAL STUDIES (Romanian)
• METHODOLOGY REGARDING THE GRANT OR REVOCATION OF THE COMPETENCE OF DOCTORAL SUPERVISOR WITHIN SCOSAAR (APPENDICES)
• METHODOLOGY REGARDING THE ORGANIZATION AND DOCTORAL THESIS PRESENTATION (APPENDICES)
• GUIDE FOR THE PREPARATION AND EDITING OF THE PHD THESIS WITHIN THE SCHOOL OF ADVANCED STUDIES OF THE ROMANIAN ACADEMY – SCOSAAR EDITING GUIDE (APPENDICES)
• METHODOLOGY REGARDING THE GRANT OF SCHOLARSHIPS FOR UNIVERSITY DOCTORAL STUDIES (APPENDICES)
• METHODOLOGY REGARDING THE SITUATIONS OF EXTENSION OR TERMINATION OF THE STUDENT-PhD (APPENDICES).
• METHODOLOGY REGARDING THE EVALUATION OF DOCTORAL SUPERVISORS BY DOCTORAL STUDENTS (APPENDICES)
• METHODOLOGY FOR ANALYSIS AND APPROVAL OF UNIVERSITY DOCTORAL STUDIES PROGRAMS
• METHODOLOGY REGARDING THE DOCTORATE IN CO-SUPERVISION (A1, A2, A3, A4, A5, A6, A7, A8)(Romanian)
• METHODOLOGY REGARDING THE DOCTORATE IN CO-SUPERVISION (English)
• METHODOLOGY REGARDING ACADEMIC MOBILITY OF DOCTORAL STUDENTS (APPENDICES)
• METHODOLOGY REGARDING THE CHANGE OF PhD SUPERVISOR AND CONFLICT MEDIATION
• METHODOLOGY REGARDING THE TRANSFER OF TRAINING RESULTS BETWEEN STUDY PROGRAMS
• MECHANISMS FOR RECOGNITION OF PhD SUPERVISOR QUALITY
• CONTRACT FOR UNIVERSITY DOCTORAL STUDIES WITH A BURSARY
• CONTRACT FOR UNIVERSITY DOCTORAL STUDIES WITHOUT A BURSARY
• CONTRACT FOR UNIVERSITY DOCTORAL STUDIES WITH CO-SUPERVISION AND WITH BURSARY
• CONTRACT FOR UNIVERSITY DOCTORAL STUDIES WITH CO-SUPERVISION AND WITHOUT BURSARY
• UNIVERSITY DOCTORAL STUDIES PLAN (English)
• UNIVERSITY DOCTORAL STUDIES PLAN (Romanian)
• AGREEMENT REGARDING PERSONAL DATA PROCESSING (English)
• AGREEMENT REGARDING PERSONAL DATA PROCESSING (Romanian)
• QUESTIONNAIRE FOR EVALUATING THE SATISFACTION OF THE DOCTORAL STUDENT
APPENDICES FOR PhD ACTIVITY 2022-2023
PhD THESIS ARCHIVE
