SCHOOL OF ADVANCED STUDIES OF THE ROMANIAN ACADEMY (SCOSAAR)

The doctoral program of the Stefan S Nicolau Institute of Virology is part of the school of advanced studies of the Romanian Academy (SCOSAAR). The program is aimed at graduates with higher education in natural sciences or medicine who want an academic training in medicine.

DOCTORAL TRAINING PROGRAM

THE RESEARCH AREA COVERED BY THE PhD PROGRAM

1. Viral infections with a major impact on public health (HIV infection, viral hepatitis, flu, CNS infections, emerging viruses).

2. Mechanisms involved in the pathogenesis of viral infections (viral infections in non-communicable diseases).

3. Molecular and cellular biology (including genetic and epigenetic factors) in human pathology.

4. Immunology, especially the subfield of tumor immunology.

5. Modulation of some biological processes.

6. Biotechnology/nanomedicine (in vitro studies on the biological effects induced by nanoparticles loaded with drugs/natural compounds).

7. Biology of tumor stem cells; the study of multiple drug resistance; in vitro studies on immunotherapeutic approaches in cancer.

8. Medical applications of new technologies (NGS-next generation sequencing, ChIP immunoprecipitation of chromatin, microarray).

9. Pharmacology, Pharmacokinetics.

10. Public health.

DOCTORAL RESEARCH DIRECTIONS IN STEFAN S. NICOLAU INSTITUTE OF VIROLOGY

VIROLOGY – PhD supervisor – Simona Ruţă, PhD

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Simona Ruţă is Professor of Virology and Vice-Rector for scientific research at the Carol Davila University of Medicine and Pharmacy in Bucharest, principal investigator, department for Emerging Viral Diseases, Ştefan S. Nicolau Institute of Virology and founding director of the International Center for research in the field of HIV/AIDS affiliated to the Baylor Pediatric AIDS Initiative, Texas, Houston, USA. She is corresponding member of the Academy of Medical Sciences and member of the Educational Subcomittee of the European Society for Clinical Microbiology and Infectious Diseases. Her main fields of research are the molecular epidemiology of HIV and viral hepatitis infections (antigenic heterogenicity of HIV strains circulating in Romania; emergence of HIV/HBV/HCV strains resistant to antiretrovirals), the impact of HIV on the central nervous system and the evolution of neurotropic emergent viral diseases. Author of over 100 articles indexed in international data bases, 54 in the Clarivate/ISI database with a cumulative factor >90 and more than 1000 citations. Project director or member in the research team of more than 30 national and international grants. 

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Education: B.S from University of Polytechnics from Bucharest, Faculty of Chemistry, Biochemistry Department (now, Biochemistry Faculty from University of Bucharest) (in 1984); PhD fellow at Centro Regionale Oncologico di Aviano, Italy, in the Advanced Immunotherapy Department (1993-1996); PhD in Biology, Biochemistry specialization, since 1999. Present position – Head of the Center of Immunology from Stefan. S. Nicolau Institute for Virology (IVN) (since 2000), Senior Researcher (Ist degree, since 2006), PhD supervisor in Medicine (Immunology sub-domain, since 2006). Member of the Romanian Society of Immunology (affiliated to IUIS, EFIS, BAIS – since 1996), the Romanian Society of Biochemistry and Molecular Biology (affiliated to FEBS – since 2000), the Romanian Society for Cytometry (affiliated to ISAC – since 2008). Domains of interest: immunology, especially tumour immunology (biomarkers; tumour resistance; apoptosis; cancer stem cells), immunotherapeutical aproaches in cancer, molecular biology, nanomedicine (nanoparticles, organometallic and bioactive compounds), natural compounds. Technical skills and competences: cell cultures; cell-, complement- and drug-mediated cytotoxicity assays; ELISA; flow-cytometry techniques (apoptosis, cell cycle, antigen expression); Real-Time Cell Analysis (RTCA); RT-PCR approaches; SDS-PAGE/ Western blotting. Scientific activity: co-author of 1 book, 5 book chapters, 1 research patent, 57 published papers (30 ISI journals and 29 in peer-reviewed scientific journals); over 250 oral presentations and posters since 2005, presented in national (114) and international (142) conferences, and published as abstracts. Research activity focused on: tumor biomarkers (expression, functional roles); modulation of biomarker expression, biologic activities and signal transduction pathways by cytokines, natural compounds, anti-cancer drugs, nanoparticles; multi-drug resistance; imortalization of tumor cells from solid tumors; cancer stem-like cell cultures and characterization; complement regulators; apoptosis and cell-cycle key regulators. Management activities: Director/partner in national scientific projects; member of management council/team in European funded research projects (COST, POC, POS-CCE).The research abilities and good experience were acumulated in managing 3 international projects (1 as co-director, 2 as member of Management Council) and 16 national projects (11 as director, 5 as responsible partner); as a team member in 7 international projects and over 23 national research grants.

MOLECULAR BIOLOGY – PhD supervisor – Gabriela Anton, PhD

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Anton Gabriela, principal investigator, Molecular Virology Department, „Stefan S Nicolau” Institute of Virology, PhD supervisor in the field of medicine at the Romanian Academy. The research areas of interest cover genetic and epigenetic modifications in human pathologies and medical applications for „omic” technologies. Has authored over 200 scientific papers and communications (h index – 11), over 750 citations, out of which 500 in 2016 alone; project leader and team member in over 25 competition won projects; member of Romanian Biochemestry and Molecular Biology Society (FEBS affiliated), of Romanian Immunology Society (IUIS, EFIS and BAIS affiliated) and since 2005 member of European Association of Cancer Research (EACR); project evaluator for national and international competitions (EuroNanoMed).

TOXICOLOGY – PHARMACOLOGY – PhD supervisor – Acad. Victor Voicu, PhD

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Academician Victor Voicu is the vicepresident of Romanian Academy Science since 2018, member of the Romanian Academy since 2001 (corresponding since 1991), president of Toxicology and Toxicodependence Commission in Ministry of Health (1998-2015), president of Scientific Council in Romanian National Medicine Agency (1997-2009). He is a university professor of Clinical Pharmacology, Toxicology and Psychopharmacology at the “Carol Davila” University of Medicine and Pharmacy in Bucharest and the President of the Romanian Society of Pharmacology, Therapeutics and Clinical Toxicology and also, member of the International Federation of Pharmaceutical Sciences, the European College of Neuropsychopharmacology, the American Chemical Society, the American College of Clinical Pharmacology. In 2005, he received the title of Doctor honoris causa from the “Ovidius” University in Constanta and the “Vasile Goldiş” University in Arad. On December 1, 2017 acad. Victor Voicu was decorated by the Presidency of Romania with the National Order “Steaua României” in the rank of Commander.  Academician Victor Voicu is the author of over 20 monographic volumes, 300 published and communicated scientific works and holds almost 30 invention patents.

PUBLIC HEALTH – PhD supervisor – Daniela Mănuc, PhD

1 – Public health –

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2 – Preventive dentistry

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3 – Management in the oral medicine office

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Daniela Manuc, PhD Professor at the “Carol Davila” University of Medicine and Pharmacy, Bucharest, Faculty of Dental Medicine, Public Health Discipline. As responsibilities, Professor Manuc coordinates the activity of doctoral students and residents in the specialty Public Health and Management, coordination of undergraduate theses. Professor Manuc developed a series of works in the field of dental practice, as well as public health management and the ethics of medical professions in relation to patients. Between 2015 and 2017 she was Director – Senior Advisor in the Ministry of European Funds/ Ministry of Labor and Social Protection/ MDRAPFE – Management Authority for Sectoral Operational Program Human Resources Development/ General Directorate of Human Capital Programs. In 2016, was Head of Program Implementation and Coordination Unit – Ministry of Health. Between 2012 and 2016, was Deputy General Director of the Ministry of European Funds/Ministry of Labor and Social Protection – Management Authority for the Human Resources Development Sectoral Operational Program. Between 2001 and 2009 was Deputy General Director/ Head of the Program Implementation and Coordination Unit/ Director of Public Health – Ministry of Health.

VETERINARY MEDICINE- PhD supervisor – Nicolae Manolescu, PhD

Nicolae Manolescu is University professor Honoris Causa, Doctor Honoris Causa, professor Emeritus, correspondent member of the Romanian Academy, a corresponding member of the French Academy of Medicine. Doctoral supervisor at the School of Advanced Studies of the Romanian Academy, Veterinary Medicine Field; Scientific director – Spiru Haret University, Bucharest; Professor Pathological Anatomy Department, Spiru Haret University, Faculty of Veterinary Medicine; Founding president of the Association One Health-New Medical Concept, Romania. President of Section at the Academy of Medical Sciences – Comparative Medicine Section Fields of competence:  pathological anatomy, comparative oncology, cell pathology, biotechnology.

PhD ADMISSIONS

Required documents for the registration to the doctoral colloquium:

  • birth certificate (legalized copy);
  • baccalaureate diploma (certified copy);
  • marriage certificate or other name change document (legalized copy);
  • identity card (xerox copy);
  • bachelor’s degree and transcript (certified copies);
  • master’s degree and transcript (certified copies);
  • certificate of passing a language proficiency exam (minimum level B2, according to the reference framework of the Council of Europe);
  • other certificates attesting university and/or postgraduate training in the field (legalized copies);
  • curriculum vitae – European model (Part I – CV, Part II – descriptionscientific activity);
  • the list of scientific works published in the chosen field of study;
  • the bibliographic list with the specialized literature studied for the admission interview;
  • personal details file (Standard document 2)
  • proposal regarding the doctoral thesis to be developed and a brief presentation of to it – 1.2 pages (Standard document 3)
  • employee certificate if the candidate is employed;
  • for foreign citizens – the certificate of linguistic competence regarding the knowledge of the Romanian language/or to submit certificates/diplomas proving at least 4 consecutive years of studies in Romania.
  • Doctoral enrollment fee (10 Euro, payable at the cashier’s office)

STRUCTURE OF THE DOCTORAL TRAINING PROGRAM

Doctoral university studies are planned for a period of 4 academic years and include:

  1. A training program based on advanced university studies, completed within a doctoral school and made up of activities carried out in institutionalized study formations;
  2. An individual program of scientific research/artistic creation.

The first year of doctoral studies includes the training program based on advanced university studies, which includes mandatory subjects:

  1. Scientific research methodology;
  2. Ethic and academic integrity;
  3. Structural and functional genomics.

The field of research covered by the doctoral program also includes the disciplines:

  1. Virology;
  2. Public healt;
  3. Molecular biology;
  4. Immunology;
  5. Toxicology

At least 4 disciplines are mandatory.

The second year consists of setting up the research plan, establishing the objectives, perfecting the methodology, recruiting the study group and presenting a scientific report on a theme derived from the paper.

The third year consists of the analysis of the study material, the development of the statistical apparatus, the follow-up of the specialized literature on the established topic and the presentation of a scientific report on a topic derived from the paper.

Year IV is the year of writing, finalizing and presenting the thesis.

During years II, III, IV, the doctoral student will present information regarding the progress stage of the thesis.

Doctoral studies end with the public submission of an original work (doctoral thesis), which is the result of the research or artistic creation carried out by the doctoral student during the doctoral university studies. Based on the doctorate thesis and its public support, it is decided whether or not to award the doctorate.

ACTIVITATEA  DE DOCTORAT ACTUALĂ ȘI ANTERIOARA

SCOSAAR METHODOLOGIES

METODOLOGIA ORGANIZARII SI DESFASURARII CONCURSULUI DE ADMITERE LA STUDIILE UNIVERSITARE DE DOCTORAT (English)

METODOLOGIA ORGANIZARII SI DESFASURARII CONCURSULUI DE ADMITERE LA STUDIILE UNIVERSITARE DE DOCTORAT

METODOLOGIA PRIVIND ACORDAREA SI REVOCAREA CALITATII DE CONDUCATOR DE DOCTORAT IN CADRUL SCOSAAR (ANEXE)

METODOLOGIA ORGANIZARII SI SUSTINERII TEZEI DE DOCTORAT (ANEXE)

GHID DE INTOCMIRE SI REDACTARE A TEZEI DE DOCTORAT IN CADRUL SCOLII DE STIDII AVANSATE A ACADEMIEI ROMANE- SCOSAAR (ANEXE)

METODOLOGIA PRIVIND ACORDAREA BURSELOR PENTRU STUDII UNIVERSITARE DE DOCTORAT (ANEXE)

METODOLOGIA PRIVIND SITUATIILE DE PRELUNGIRE SAU INCETARE A CALITATII DE STUDENT-DOCTORAND

METODOLOGIA DE EVALUARE A CONDUCATORILOR DE DOCTORAT DE CATRE STUDENTII DOCTORANZI INMATRICULATI LA SCOSAAR (ANEXE)

METODOLOGIA PENTRU ANALIZA SI APROBAREA TEMATICILOR OROGRAMELOR DE STUDII UNIVERSITARE DE DOCTORAT

METODOLOGIA PRIVIND DOCTORATUL IN COTUTELA (A1, A2, A3, A4, A5, A6, A7, A8)

METODOLOGIA PRIVIND DOCTORATUL IN COTUTELA (English)

METODOLOGIE PRIVIND MOBILITATEA ACADEMICA A STUDENTILOR DOCTORANZI (ANEXE)

METODOLOGIA DE SCHIMBARE A CONDUCATORULUI DE DOCTORAT SI MEDIERE A CONFLICTELOR

• METODOLOGIA PRIVIND TRANSFERUL REZULTATELOR FORMATIVE INTRE PROGRAMELE DE STUDII

MECANISMELE DE RECUNOASTERE A CALITATII DE CONDUCATOR DE DOCTORAT

ACORD DE COTUTELA PRIVIND DOCTORATUL INTERDISCIPLINAR INCHEIAT INTRE ACADEMIA ROMANA SCOSAAR SI UNIVERSITATEA…

ACORD DE COTUTELA PRIVIND DOCTORATUL INTERDISCIPLINAR INCHEIAT INTRE ACADEMIA ROMANA SCOSAAR SI UNIVERSITATE…(English)

ACORD PRIVIND PRELUCRAREA DATELOR CU CARACTER PERSONAL (English)

ACORD PRIVIND PRELUCRAREA DATELOR CU CARACTER PERSONAL

CHESTIONAR DE EVALUARE A SATISFACTIEI STUDENTULUI DOCTORAND

PhD THESIS ARCHIVE

YEARPhD STUDENT NAMEPhD THESISCONFIRMATION ORDERS OF THE MINISTER OF EDUCATION REGARDING THE GRANTING OF THE DOCTORATE
2023DIANA-GABRIELA IACOBRISK FACTORS FOR LIVER FIBROSISIN PATIENTS WITH HIV, HIV-HBV AND HBV INFECTIONOrdinul OME de confirmare Nr. 5277/04.08.2023
2022CARMEN-VALENTINA CRISTESCUHUMAN CYTOMEGALOVIRUS INFECTION AND THE RISK OF CARDIOVASCULAR DISEASEOrdinul OME de confirmare Nr. 3977/19.04.2023
2022ANCA GABRIELA PAVELMOLECULAR PROFILES ASSOCIATED WITH PROSTATE CANCEROrdinul OME de confirmare Nr. 3140/25.01.2023
2022AURELIAN-CORNELIU MORARU RESEARCH ON THE INVOLVEMENT OF SOME STRESS FACTORS IN THE ETIOPATHOGENESIS OF SOME DERMATOLOGICAL CONDITIONSOrdinul OME de confirmare Nr. 6471/28.12.2022
2021IOANA-MĂDĂLINA ALDEACELLULAR AND MOLECULAR MECHANISMS INVOLVED IN THE RESPONSE TRIGGERED BY THE ACTION OF ANTIVIRAL COMPOUNDSOrdinul OME de confirmare Nr. 4640/18.08.2021
2021REMUS IULIAN NICAREDUCED RISK FACTORS IN SPORADIC FORMS OF BREAST CANCEROrdinul OME de confirmare Nr. 4640/18.08.2021
2020SIMONA MIHAI DIACONUCHALLENGES IN THE EARLY DIAGNOSIS OF MAJOR DISEASES BY ADDRESSING PROTEOMIC TECHNOLOGIESOrdinul OME de confirmare Nr. 3461/08.03.2021
2020ANA-MARIA COMAN (BURDUŞEL)NEWS IN THE FIELD OF LYMPH NODES CYTOMORPHOLOGY IN HORSE AND SHEEP, IDENTIFIED TO ANIMALS SACRIFIED UNDER SLAUGHTERHOUSE CONDITIONSOrdinul OME de confirmare Nr. 5748/13.10.2020
2019DANIELA GLĂVANTHE ROLE OF PROTEINASES IN ANGIOGENESIS AND TUMOUR PROLIFERATIONOrdinul MEN de confirmare Nr. 5308/20.11.2019
2019MARIA MONICA VASILESCUINVOLVEMENT OF TOPOISOMERASES IN TUMOR CELLS RESISTANCE TO TREATMENT WITH CHEMOTHERAPEUTIC AGENTSOrdinul MEN de confirmare Nr. 4517/22.07.2019
2018RUXANDRA BURLACUNEUROCOGNITIVE COMPLICATIONS ASSOCIATED WITH EARLY SENESCENCE IN CHILDREN AND ADOLESCENTS PARENTERALLY INFECTED IN CHILDHOODOrdinul MEN de confirmare Nr. 5745 /28.12.2018
2018CORNELIU PETRU POPESCUCORRELATIONS BETWEEN ETIOLOGY AND PROGNOSIS OF VIRAL INFECTIONS OF THE CENTRAL NERVOUS SYSTEMOrdinul MEN de confirmare Nr. 3693/19.03.2019
2018IRINA – CRISTIANA IANACHEPARENTERAL INFECTIONS IN ROMANIAN INJECTING DRUG USERSOrdinul MEN de confirmare Nr. 4193/07.08.2018
2018SUSANA VILMA VLĂDOIUGENETIC, EPIGENETIC AND HORMONAL CHANGES IN MALE INFERTILITYOrdinul MEN de confirmare Nr. 5474/14.11.2018
2017DANIELA MURĂRAŞUTHE STUDY OF GENETIC AND EPIGENETIC CHANGES OF THE FACTORS ASSOCIATED WITH EPITHELIAL CANCERSOrdinul MEN de confirmare Nr. 3779/04.06.2018
2017LAURA DENISA DRAGUDEVELOPMENT OF A TARGETED MOLECULAR THERAPY STRATEGY IN GASTRIC CANCEROrdinul MEN de confirmare Nr. 3779/04.06.2018
2017GEORGIANA-GABRIELA PETRICĂ-MATEITHE STUDY OF SOME CELLULAR AND MOLECULAR MECHANISMS INVOLVED IN THE TRANSFORMATION, INVASION AND METASTASIS OF TUMOR CELLS IN ORL CANCEROrdinul MEN de confirmare Nr. 5701/29.12.2017
2017ANA-IULIA NEAGUSTUDIES ON THE ROLE OF REGULATORY T LYMPHOCYTES IN THE PATHOGENESIS AND PERSISTENCE OF MYCOBACTERIUM TUBERCULOSIS INFECTIONOrdinul MEN de confirmare Nr. 3779/04.06.2018
2017MIA CAMELIA HOTNOGGENETIC AND IMMUNOLOGICAL FACTORS INVOLVED IN TUMOR PROGRESSION AND ANGIOGENESISOrdinul MEN de confirmare Nr. 5701/29.12.2017
2017COMAN DRAGOS-CONSTANTINSTUDY OF CYTOMORPHOLOGICAL CHANGES IN PRENEOPLASIC HEMATOPOIESIS IN PIGS AND CATTLE SACRIFICED IN SLAUGHTER HOUSE CONDITIONSOrdinul OME de confirmare Nr. 4640/18.08.2021
2016BOGDAN SILVIU STREZATHE COMPARATIVE VALUE OF PHARMACOTHERAPY AND SURGICAL TREATMENT IN URINARY INCONTINENCE IN WOMENOrdinul MEN de confirmare Nr. 5321/29.09.2016
2016ADELINA-ANA ROȘCAmicroRNA IN VIRAL INFECTIONOrdinul MEN de confirmare Nr. 3769/20.04.2017